Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation

Pathway Analysis of Glioblastoma Tissue after Preoperative Treatment with the EGFR Tyrosine Kinase Inhibitor Gefitinib--A Phase II Trial

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Caspase-8-mediated cleavage of Bid and protein phosphatase 2A-mediated activation of Bax are necessary for Verotoxin-1-induced apoptosis in Burkitt's lymphoma cells

(2009) Julie Garibal et al.   CELLULAR SIGNALLING

EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts

(2009) B. Lal et al.   MOLECULAR CANCER THERAPEUTICS

Amphiregulin Promotes BAX Inhibition and Resistance to Gefitinib in Non-small-cell Lung Cancers

(2009) Benoît Busser et al.   MOLECULAR THERAPY

PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

(2009) Q Sun et al.   ONCOGENE

An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells

(2008) Gee-Chen Chang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts

(2008) Birgit Geoerger et al.   INTERNATIONAL JOURNAL OF CANCER

Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status

(2008) Catia Cemeus et al.   JOURNAL OF NEURO-ONCOLOGY

Cyclosporine A prevents apoptosis-related mitochondrial dysfunction after neonatal cardioplegic arrest

(2008) Norihiko Oka et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

The BCL-2 protein family: opposing activities that mediate cell death

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