Journal
JOURNAL OF NEURO-ONCOLOGY
Volume 90, Issue 1, Pages 25-30Publisher
SPRINGER
DOI: 10.1007/s11060-008-9622-5
Keywords
central neurocytoma; conventional radiation therapy; long-term outcome
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Funding
- Cancer Research Institute of Seoul National University
- Clinical Research institute of Seoul National University Hospital
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The authors report the long-term outcome of conventional radiation therapy (RT) in six cases of central neurocytoma (CN). Between 1985 and 1992, six patients were treated with RT for residual tumors or for prevention of recurrence after surgery. The median follow-up period of radiological and clinical status were 171 (range: 128-229) and 202 months (range: 165-227), respectively. Tumors disappeared in three and reduced in three patients at the last follow-up. One-mortality case due to radiation necrosis and one radiation-induced malignancy occurred. White matter degeneration and cortical atrophy were noticed with slow progression of performance deterioration in two patients. Conventional RT seemed to effectively control residual CN after surgery. However, more sophisticated radiation techniques should be applied to minimize the late sequela.
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