Deuterium-substituted l-DOPA displays increased behavioral potency and dopamine output in an animal model of Parkinson’s disease: comparison with the effects produced by l-DOPA and an MAO-B inhibitor

Increased L-DOPA-derived dopamine following selective MAO-A or -B inhibition in rat striatum depleted of dopaminergic and serotonergic innervation

(2013) O Sader-Mazbar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chronic monoamine oxidase-B inhibitor treatment blocks monoamine oxidase-A enzyme activity

(2013) Jasmin Bartl et al.   JOURNAL OF NEURAL TRANSMISSION

Dopamine release from serotonergic nerve fibers is reduced in L-DOPA-induced dyskinesia

(2011) Nina Nevalainen et al.   JOURNAL OF NEUROCHEMISTRY

Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats

(2011) Christopher J. Barnum et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Deuterium substitutions in the L-DOPA molecule improve its anti-akinetic potency without increasing dyskinesias

(2010) Torun Malmlöf et al.   EXPERIMENTAL NEUROLOGY

Serotonergic neurons mediate ectopic release of dopamine induced by l-DOPA in a rat model of Parkinson's disease

(2010) Sylvia Navailles et al.   NEUROBIOLOGY OF DISEASE

l-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson’s disease: temporal and quantitative relationship to the expression of dyskinesia

(2009) Hanna S. Lindgren et al.   JOURNAL OF NEUROCHEMISTRY

Relationship between weight, levodopa and dyskinesia: the significance of levodopa dose per kilogram body weight

(2008) J. C. Sharma et al.   EUROPEAN JOURNAL OF NEUROLOGY

Levodopa-Induced Dyskinesias in Parkinson’s Disease: Etiology, Impact on Quality of Life, and Treatments

(2008) Elmyra V. Encarnacion et al.   EUROPEAN NEUROLOGY

Altered behavioural and neurochemical profile of l-DOPA following deuterium substitutions in the molecule

(2008) Torun Malmlöf et al.   EXPERIMENTAL NEUROLOGY

Pharmacokinetics and pharmacodynamics of levodopa

(2008) John G. Nutt   MOVEMENT DISORDERS