Involvement of kynurenines in Huntington’s disease and stroke-induced brain damage

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction

(2010) G. Matteoli et al.   GUT

Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion

(2010) Sun-Mi Lee et al.   IMMUNOLOGY LETTERS

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

IDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis

(2010) Y. Yan et al.   JOURNAL OF IMMUNOLOGY

The Role of Tryptophan Catabolism along the Kynurenine Pathway in Acute Ischemic Stroke

(2010) Raf Brouns et al.   NEUROCHEMICAL RESEARCH

Anti-infectious Activity of Tryptophan Metabolites in the L-Tryptophan–L-Kynurenine Pathway

(2009) Koji Narui et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis

(2009) J. Rodgers et al.   BRAIN

Pathophysiology of Huntingtonʼs disease: from huntingtin functions to potential treatments

(2009) Emmanuel Roze et al.   CURRENT OPINION IN NEUROLOGY

HLA-G: a human pregnancy-related immunomodulator

(2009) Joan S Hunt et al.   CURRENT OPINION IN PHARMACOLOGY

Blood levels of kynurenines, interleukin-23 and soluble human leucocyte antigen-G at different stages of Huntington’s disease

(2009) Caroline M. Forrest et al.   JOURNAL OF NEUROCHEMISTRY

In Vivo Evidence for NMDA Receptor-Mediated Excitotoxicity in a Murine Genetic Model of Huntington Disease

(2009) M. Y. Heng et al.   JOURNAL OF NEUROSCIENCE

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

(2009) Ashwani K Thakur et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

(2009) Robert Schwarcz et al.   PROGRESS IN NEUROBIOLOGY

Targeting oxidative/nitrergic stress ameliorates motor impairment, and attenuates synaptic mitochondrial dysfunction and lipid peroxidation in two models of Huntington's disease

(2008) Verónica Pérez-De La Cruz et al.   BEHAVIOURAL BRAIN RESEARCH

Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds

(2008) Javier Gayán et al.   GENETIC EPIDEMIOLOGY

Effect of 3-hydroxyanthranilic acid in the immunosuppressive molecules indoleamine dioxygenase and HLA-G in macrophages

(2008) Ana S. López et al.   IMMUNOLOGY LETTERS

IDO: A double-edged sword for TH1/TH2 regulation

(2008) Hui Xu et al.   IMMUNOLOGY LETTERS

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Polyglutamine-Modulated Striatal Calpain Activity in YAC Transgenic Huntington Disease Mouse Model: Impact on NMDA Receptor Function and Toxicity

(2008) C. M. Cowan et al.   JOURNAL OF NEUROSCIENCE

Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse

(2008) B.R. Miller et al.   NEUROSCIENCE