Are cyclooxygenase-2 and nitric oxide involved in the dyskinesia of Parkinson's disease induced by l-DOPA?

Glial activation is associated with l-DOPA induced dyskinesia and blocked by a nitric oxide synthase inhibitor in a rat model of Parkinson's disease

(2015) Mariza Bortolanza et al.   NEUROBIOLOGY OF DISEASE

Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3−/− aphakia mice

(2015) Oscar Solís et al.   NEUROBIOLOGY OF DISEASE

Effects of prolonged neuronal nitric oxide synthase inhibition on the development and expression of l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats

(2015) Fernando Eduardo Padovan-Neto et al.   NEUROPHARMACOLOGY

Angiotensin type 1 receptor blockage reduces l-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of vascular endothelial growth factor and interleukin-1β

(2014) Ana Muñoz et al.   EXPERIMENTAL NEUROLOGY

Striatal Cholinergic Cell Ablation Attenuates L-DOPA Induced Dyskinesia in Parkinsonian Mice

(2014) L. Won et al.   JOURNAL OF NEUROSCIENCE

Differential Effects of Synaptic and Extrasynaptic NMDA Receptors on A -Induced Nitric Oxide Production in Cerebrocortical Neurons

(2014) E. Molokanova et al.   JOURNAL OF NEUROSCIENCE

Local control of striatal dopamine release

(2014) Roger Cachope et al.   Frontiers in Behavioral Neuroscience

Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications

(2014) M. Angela Cenci   Frontiers in Neurology

Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications

(2013) Daniela Salvemini et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Anti-dyskinetic effect of the neuronal nitric oxide synthase inhibitor is linked to decrease of FosB/DeltaFosB expression

(2013) Fernando Eduardo Padovan-Neto et al.   NEUROSCIENCE LETTERS

Counteraction by Nitric Oxide Synthase Inhibitor of Neurochemical Alterations of Dopaminergic System in 6-OHDA-Lesioned Rats Under l-DOPA Treatment

(2013) Elaine Del-Bel et al.   NEUROTOXICITY RESEARCH

IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates

(2013) Romina Aron Badin et al.   PLoS One

Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian rats

(2012) Kazuhiro Takuma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease

(2012) Louise M. Collins et al.   NEUROPHARMACOLOGY

7-Nitroindazole down-regulates dopamine/DARPP-32 signaling in neostriatal neurons in a rat model of Parkinson's disease

(2012) J.E. Yuste et al.   NEUROPHARMACOLOGY

Extrasynaptic Neurotransmission in the Modulation of Brain Function. Focus on the Striatal Neuronal–Glial Networks

(2012) Kjell Fuxe et al.   Frontiers in Physiology

Investigations into Potential Extrasynaptic Communication between the Dopaminergic and Nitrergic Systems

(2012) M. Mitkovski et al.   Frontiers in Physiology

Role of Nitric Oxide in Motor Control: Implications for Parkinson's Disease Pathophysiology and Treatment

(2011) Elaine Del-Bel et al.   CURRENT PHARMACEUTICAL DESIGN

Synaptic and Extrasynaptic NMDA Receptors Differentially Modulate Neuronal Cyclooxygenase-2 Function, Lipid Peroxidation, and Neuroprotection

(2011) D. T. Stark et al.   JOURNAL OF NEUROSCIENCE

Dopamine release in the basal ganglia

(2011) M.E. Rice et al.   NEUROSCIENCE

Contribution of pre-synaptic mechanisms to l-DOPA-induced dyskinesia

(2011) M. Carta et al.   NEUROSCIENCE

The role of nitric oxide in prostaglandin biology; update

(2011) Sangwon F. Kim   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation

(2011) Mario Gustavo Murer et al.   Frontiers in Neuroanatomy

Lack of tolerance for the anti-dyskinetic effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in rats

(2010) N. Novaretti et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Non-synaptic receptors and transporters involved in brain functions and targets of drug treatment

(2010) ES Vizi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2010) Francesca L'Episcopo et al.   Journal of Neuroinflammation

Striatal Overexpression of  FosB Reproduces Chronic Levodopa-Induced Involuntary Movements

(2010) X. Cao et al.   JOURNAL OF NEUROSCIENCE

Inflammation and Parkinson's disease pathogenesis

(2010) Serge Przedborski   MOVEMENT DISORDERS

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

BN82451 attenuates l-dopa-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson’s disease

(2010) Brigitte Spinnewyn et al.   NEUROPHARMACOLOGY

Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice

(2010) Y. Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calbindin-1association and Parkinson’s disease

(2009) A. I. Soto-Ortolaza et al.   EUROPEAN JOURNAL OF NEUROLOGY

Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders

(2009) Valerie Voon et al.   LANCET NEUROLOGY

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE2 activation

(2009) Wen-Ta Chiu et al.   NEUROBIOLOGY OF DISEASE

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Nitric oxide synthase inhibition attenuates l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease

(2009) F.E. Padovan-Neto et al.   NEUROSCIENCE

CXCR4 and CXCL12 Expression is Increased in the Nigro-Striatal System of Parkinson’s Disease

(2009) Mika Shimoji et al.   NEUROTOXICITY RESEARCH

Calcium homeostasis, selective vulnerability and Parkinson's disease

(2009) C. Savio Chan et al.   TRENDS IN NEUROSCIENCES

The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

(2009) Sang-Ho Choi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology

(2008) K. Fuxe et al.   BRAIN RESEARCH REVIEWS

Dopamine spillover after quantal release: Rethinking dopamine transmission in the nigrostriatal pathway

(2008) Margaret E. Rice et al.   BRAIN RESEARCH REVIEWS

Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2

(2008) Saba Aid et al.   Journal of Neuroinflammation

Molecular mechanisms of L-DOPA-induced dyskinesia

(2008) Peter Jenner   NATURE REVIEWS NEUROSCIENCE

Exogenous corticosterone reduces l-DOPA-induced dyskinesia in the hemi-parkinsonian rat: Role for interleukin-1β

(2008) C.J. Barnum et al.   NEUROSCIENCE

S-nitrosylation/activation of COX-2 mediates NMDA neurotoxicity

(2008) J. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient mice

(2007) Christopher D. Toscano et al.   BRAIN RESEARCH BULLETIN

Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: A bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats

(2007) Kerstin Buck et al.   NEUROBIOLOGY OF DISEASE