Illuminating neural circuits and behaviour inCaenorhabditis eleganswith optogenetics

Feedback from Network States Generates Variability in a Probabilistic Olfactory Circuit

(2015) Andrew Gordus et al.   CELL

Dual Color Neural Activation and Behavior Control with Chrimson and CoChR in Caenorhabditis elegans

(2015) Lisa C. Schild et al.   GENETICS

Metabotropic Glutamate Receptors

(2015) James Dillon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Light and Hydrogen Peroxide Inhibit C. elegans Feeding through Gustatory Receptor Orthologs and Pharyngeal Neurons

(2015) Nikhil Bhatla et al.   NEURON

Neuronal Activity and CaMKII Regulate Kinesin-Mediated Transport of Synaptic AMPARs

(2015) Frédéric J. Hoerndli et al.   NEURON

Decoding a neural circuit controlling global animal state in C. elegans

(2015) Patrick Laurent et al.   eLife

Dual Color Neural Activation and Behavior Control with Chrimson and CoChR in Caenorhabditis elegans

(2015) Lisa C. Schild et al.   GENETICS

Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants

(2014) Sybille Ullrich et al.   BIOLOGICAL CHEMISTRY

Encoding of Both Analog- and Digital-like Behavioral Outputs by One C. elegans Interneuron

(2014) Zhaoyu Li et al.   CELL

Multilevel Modulation of a Sensory Motor Circuit during C. elegans Sleep and Arousal

(2014) Julie Y. Cho et al.   CELL

FMRFamide-like FLP-13 Neuropeptides Promote Quiescence following Heat Stress in Caenorhabditis elegans

(2014) Matthew D. Nelson et al.   CURRENT BIOLOGY

Neural and genetic degeneracy underlies Caenorhabditis elegans feeding behavior

(2014) Nicholas F. Trojanowski et al.   JOURNAL OF NEUROPHYSIOLOGY

Neuronal Regeneration in C. elegans Requires Subcellular Calcium Release by Ryanodine Receptor Channels and Can Be Enhanced by Optogenetic Stimulation

(2014) L. Sun et al.   JOURNAL OF NEUROSCIENCE

Construction of a system for single-cell transgene induction in Caenorhabditis elegans using a pulsed infrared laser

(2014) Matthew A. Churgin et al.   METHODS

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Dynamic Encoding of Perception, Memory, and Movement in a C. elegans Chemotaxis Circuit

(2014) Linjiao Luo et al.   NEURON

Pulsed Irradiation Improves Target Selectivity of Infrared Laser-Evoked Gene Operator for Single-Cell Gene Induction in the Nematode C. elegans

(2014) Motoshi Suzuki et al.   PLoS One

Engineering adenylate cyclases regulated by near-infrared window light

(2014) M.-H. Ryu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

(2014) Alexander M Herman et al.   eLife

Serotonin and the Neuropeptide PDF Initiate and Extend Opposing Behavioral States in C. elegans

(2013) Steven W. Flavell et al.   CELL

An AP2 Transcription Factor Is Required for a Sleep-Active Neuron to Induce Sleep-like Quiescence in C. elegans

(2013) Michal Turek et al.   CURRENT BIOLOGY

In vivo synaptic recovery following optogenetic hyperstimulation

(2013) M. Kittelmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neuropeptide NLP-22 regulates a sleep-like state in Caenorhabditis elegans

(2013) M.D. Nelson et al.   Nature Communications

Concentration memory-dependent synaptic plasticity of a taste circuit regulates salt concentration chemotaxis in Caenorhabditis elegans

(2013) Hirofumi Kunitomo et al.   Nature Communications

Optical control of neuronal excitation and inhibition using a single opsin protein, ChR2

(2013) Holly Liske et al.   Scientific Reports

Efficient Single-Cell Transgene Induction in Caenorhabditis elegans Using a Pulsed Infrared Laser

(2013) Matthew A. Churgin et al.   G3-Genes Genomes Genetics

Monoaminergic Orchestration of Motor Programs in a Complex C. elegans Behavior

(2013) Jamie L. Donnelly et al.   PLOS BIOLOGY

PKA Controls Calcium Influx into Motor Neurons during a Rhythmic Behavior

(2013) Han Wang et al.   PLoS Genetics

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

Wnt Signaling Regulates Acetylcholine Receptor Translocation and Synaptic Plasticity in the Adult Nervous System

(2012) Michael Jensen et al.   CELL

Optogenetic Analysis of a Nociceptor Neuron and Network Reveals Ion Channels Acting Downstream of Primary Sensors

(2012) Steven J. Husson et al.   CURRENT BIOLOGY

IRK-1 Potassium Channels Mediate Peptidergic Inhibition of Caenorhabditis elegans Serotonin Neurons via a Go Signaling Pathway

(2012) L. Emtage et al.   JOURNAL OF NEUROSCIENCE

Controlling interneuron activity in Caenorhabditis elegans to evoke chemotactic behaviour

(2012) Askin Kocabas et al.   NATURE

Tonic signaling from O2 sensors sets neural circuit activity and behavioral state

(2012) Karl Emanuel Busch et al.   NATURE NEUROSCIENCE

Proprioceptive Coupling within Motor Neurons Drives C. elegans Forward Locomotion

(2012) Quan Wen et al.   NEURON

Bimodal Activation of Different Neuron Classes with the Spectrally Red-Shifted Channelrhodopsin Chimera C1V1 in Caenorhabditis elegans

(2012) Karen Erbguth et al.   PLoS One

Caenorhabditis elegans Body Mechanics Are Regulated by Body Wall Muscle Tone

(2011) Bryan C. Petzold et al.   BIOPHYSICAL JOURNAL

Food sensitizesC. elegansavoidance behaviours through acute dopamine signalling

(2011) Marina Ezcurra et al.   EMBO JOURNAL

Gap Junctions Synchronize Action Potentials and Ca2+Transients inCaenorhabditis elegansBody Wall Muscle

(2011) Ping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optogenetic analysis of GABAB receptor signaling in Caenorhabditis elegans motor neurons

(2011) Christian Schultheis et al.   JOURNAL OF NEUROPHYSIOLOGY

Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans

(2011) Jeffrey N Stirman et al.   NATURE METHODS

Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans

(2011) Andrew M Leifer et al.   NATURE METHODS

Lateral Facilitation between Primary Mechanosensory Neurons Controls Nose Touch Perception in C. elegans

(2011) Marios Chatzigeorgiou et al.   NEURON

Transfer characteristics of a thermosensory synapse in Caenorhabditis elegans

(2011) A. Narayan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Action potentials drive body wall muscle contractions in Caenorhabditis elegans

(2011) S. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neural circuits and sensory channels mediating harsh touch sensation in Caenorhabditis elegans

(2011) Wei Li et al.   Nature Communications

Optogenetic analysis of synaptic transmission in the central nervous system of the nematode Caenorhabditis elegans

(2011) Theodore H. Lindsay et al.   Nature Communications

Neural coding in a single sensory neuron controlling opposite seeking behaviours in Caenorhabditis elegans

(2011) Atsushi Kuhara et al.   Nature Communications

PACα- an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans

(2010) Simone Weissenberger et al.   JOURNAL OF NEUROCHEMISTRY

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors

(2010) Marios Chatzigeorgiou et al.   NATURE NEUROSCIENCE

C. elegans phototransduction requires a G protein–dependent cGMP pathway and a taste receptor homolog

(2010) Jie Liu et al.   NATURE NEUROSCIENCE

The Fusogen EFF-1 Controls Sculpting of Mechanosensory Dendrites

(2010) M. Oren-Suissa et al.   SCIENCE

An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition at the synapse

(2009) Ruta B Almedom et al.   EMBO JOURNAL

The Neural Network for Chemotaxis to Tastants in Caenorhabditis elegans Is Specialized for Temporal Differentiation

(2009) T. R. Thiele et al.   JOURNAL OF NEUROSCIENCE

A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans

(2009) Evan Z. Macosko et al.   NATURE

Optical interrogation of neural circuits in Caenorhabditis elegans

(2009) Zengcai V Guo et al.   NATURE METHODS

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

Channelrhodopsin-2 is a leaky proton pump

(2009) K. Feldbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional asymmetry in Caenorhabditis elegans taste neurons and its computational role in chemotaxis

(2008) Hiroshi Suzuki et al.   NATURE

Lethargus is a Caenorhabditis elegans sleep-like state

(2008) David M. Raizen et al.   NATURE

Optogenetic analysis of synaptic function

(2008) Jana F Liewald et al.   NATURE METHODS

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE

Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans

(2008) T. R. Mahoney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Molecular Solution for Ultraviolet Light Detection in Caenorhabditis elegans

(2008) Stacey L Edwards et al.   PLOS BIOLOGY

Gene Activation Using FLP Recombinase in C. elegans

(2008) M. Wayne Davis et al.   PLoS Genetics