Journal
JOURNAL OF NATURAL PRODUCTS
Volume 76, Issue 10, Pages 1930-1936Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np4005163
Keywords
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Funding
- School of Agriculture, Food and Wine, The University of Adelaide
- University of Adelaide
- China Scholarship Council
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Together with the sweet principle component glycyphyllin A (3), seven phenolic compounds including two new dihydrochalcone rhamnopyranosides, glycyphyllin B (1) and glycyphyllin C (2), and five known flavonoids, catechin (4), kaempferol-3-O-beta-D-glucopyranoside (5), quercetin-3-O-beta-D-glucopyranoside (6), kaempferol-3-O-beta-neohesperidoside (7), and 2R,3R-dihydrokaempferol-3-O-beta-D-glucopyranoside (8), have been isolated from the ethanolic extract of the leaves of Smilax glyciphylla for the first time. The structures of these compounds were characterized by spectroscopic methods including UV, MS, and ID and 2D NMR In vitro antioxidant capacity tests employing FRAP and DPPH assays indicated that 1, 4, and 6 exhibited potent antioxidant activity and are the key phenolics responsible for the antioxidant activity of the leaf extract of S. glyciphylla.
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