Journal
JOURNAL OF NATURAL PRODUCTS
Volume 75, Issue 2, Pages 220-224Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np2009169
Keywords
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Funding
- Natural Science Foundation of China [31170334, 21072198]
- National Basic Research Program of China (973 Program) [2009CB522300]
- Chinese Academy of Sciences [KSCX2-EW-R-15]
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Nine new alkaloids, melodinines M-U (1-9), and 11 known alkaloids were isolated from Melodinus suaveolens. The new structures were elucidated by extensive NMR and mass spectroscopic analyses and comparison to known compounds. All compounds were evaluated for their cytotoxicity against five human cancer cell lines. Compounds 6, 11, and 16 showed significant cytotoxicity.
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