Journal
JOURNAL OF NATURAL PRODUCTS
Volume 74, Issue 4, Pages 825-830Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np100890n
Keywords
-
Funding
- French Ministere de la Recherche
Ask authors/readers for more resources
A novel cyclodepsipeptide, iso-isariin B (1), and the known isaridin E (2) were isolated from the entomopathogenic fungus Beauveria felina. Their structures were elucidated using MS/MS fragmentation and extensive 2D-heteronuclear NMR. The X-ray structure of isaridin,E was obtained, showing two potent intramolecular H bonds and a type VI turn with the HyLeu(1)-Pro(2) amide bond in acts conformation. Iso-isariin B (1) was active against the pest-insect Sitophilus spp. with an LD50 value of 10 mu g/mL. This observation also Oyes some dues for ecological interpretation of cyclodesipeptide production by B. felina.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available