Journal
JOURNAL OF NATURAL PRODUCTS
Volume 72, Issue 7, Pages 1279-1282Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np9001948
Keywords
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Funding
- Division of Cancer Treatment and Diagnosis [CA-44344-01A1-10-12, RO1-CA90441-01-03, 5RO1-CA090441-07]
- National Cancer Institute
- DHHS
- Arizona Disease Control Research Commission
- Fannie E. Rippel Foundation
- Robert B. Dalton Endowment Fund
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To further pursue the antineoplastic leads offered by Our isolation of trans-dihydronarciclasine (1a) and 7-deoxy-trans-dihydronarciclasine (1c) from two medicinal plant species of the Amaryllidaceae family, a practical palladium-catalyzed hydrogenation procedure was developed for the synthesis of these isocarbostyrils from narciclasine (2a) and 7-deoxynarciclasine (2c).
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