Journal
JOURNAL OF NATURAL MEDICINES
Volume 67, Issue 1, Pages 78-85Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s11418-012-0651-1
Keywords
Abelmouschus manihot; Flavonol glycosides; Antioxidative activity; Aldose reductase inhibitor; DPPH scavenging activity
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Funding
- Program for Changjiang Scholars and Innovative Research Team in University [PCSIR IRT0973]
- Applied Basic and Advanced Research Program of Tianjin [10SYSYJC28900, 10ZCKFSY09300]
- Ministry of Science and Technology of China [2012ZX09103201-031]
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Bioassay-guided fractionation led to the isolation of six new flavonol glycosides, floramanosides A (1), B (2), C (3), D (4), E (5), and F (6), from the flowers of Abelmouschus manihot. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D- and 2D-NMR). Activity screening results showed that the compounds had 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities.
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