Journal
JOURNAL OF NATURAL MEDICINES
Volume 63, Issue 4, Pages 408-414Publisher
SPRINGER TOKYO
DOI: 10.1007/s11418-009-0344-6
Keywords
Glochidion rubrum; Euphorbiaceae; Lignan glucoside; Neolignan glucoside; Tachioside 2 '-O-4 ''-methylgallate
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Funding
- Ministry of Education, Science, Sports, Culture and Technology of Japan
- Japan Society for the Promotion of Science
- Ministry of Health, Labour and Welfare
- Astellas Foundation for Research on Medicinal Resources
- Takeda Science Foundation
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Thirteen compounds (1-13) were isolated from a MeOH extract of leaves of Glochidion rubrum. The structures of four new compounds were elucidated to be (-)-isolariciresinol 2a-O-beta-d-glucopyranoside (1), (7R,8S)- and (7R,8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignan 7-O-beta-d-glucopyranosides (2 and 3, respectively), and tachioside 2'-O-4aEuro(3)-O-methylgallate (4) on detailed inspection of one- and two-dimensional NMR spectral data.
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