Article
Plant Sciences
Myuri Parusnath, Yougasphree Naidoo, Moganavelli Singh, Hail Rihan, Yaser Hassan Dewir
Summary: The demand for medicinal plants is increasing due to their affordability, accessibility, and non-toxic nature. Combretum molle, commonly used in African traditional medicine, was studied to identify its phytochemical composition and functional groups using qualitative screening. Fourier transform infrared spectroscopy (FTIR), energy-dispersive X-ray (EDX) microanalyses, and fluorescence microscopy were performed to determine elemental composition and fluorescence characteristics. The results confirmed the presence of various phytochemicals and support the use of C. molle in traditional medicine.
Article
Plant Sciences
Myuri Parusnath, Yougasphree Naidoo, Moganavelli Singh, Farzad Kianersi, Yaser Hassan Dewir
Summary: This study investigated the antioxidant and antibacterial activities of various extracts from Combretum molle, a medicinal plant used in African traditional medicine. The methanol extracts showed strong radical-scavenging activity and broad-spectrum antibiotic capabilities. These findings suggest that C. molle has potential as a source for developing new drugs.
Article
Chemistry, Medicinal
Reham Z. Hamza, Najah M. Al-Bogami, Ahmed A. M. Mansour, Samy M. El-Megharbel
Summary: The study evaluated the effects of Combretum molle extract in the treatment of diabetes mellitus, showing that it reduced oxidative stress, decreased blood glucose levels, elevated insulin hormone, and lowered genotoxicity. This suggests that C. molle could be a promising therapeutic agent for diabetes with potential multimedical capabilities.
NATURAL PRODUCT COMMUNICATIONS
(2021)
Article
Horticulture
Sahejna Bantho, Yougasphree Naidoo, Yaser Hassan Dewir, Ayuvna Bantho, Hosakatte Niranjana Murthy
Summary: This study conducted a comparative analysis of the phytochemical constituents of leaf and stembark extracts of Combretum erythrophyllum, identifying a wide array of phytocompounds with potential medicinal benefits, including compounds with possible anti-cancer and anti-inflammatory properties.
Article
Horticulture
Sahejna Bantho, Yougasphree Naidoo, Yaser Hassan Dewir, Moganavelli Singh, Ayuvna Bantho
Summary: Species of Combretum, especially C. erythrophyllum, are highly valued in Africa for their traditional medicinal uses and presence of important phytometabolites. However, there is limited research on the bioactivity of C. erythrophyllum's stembark extracts compared to its leaf extracts. This study aimed to compare the biological activity of leaf and stembark extracts, evaluating various characteristics such as antioxidant, cytotoxic, and apoptosis activities.
Article
Plant Sciences
Rosemary C. Erhabor, Mutalib A. Aderogba, Joseph O. Erhabor, Sanah M. Nkadimeng, Lyndy J. McGaw
Summary: This study evaluated the antimicrobial and antioxidant activities of Combretum elaeagnoides leaf fractions and quercetin-3-O-rhamnoside compound against foodborne pathogens and their biofilms. The results showed that the fractions and compound exhibited strong antimicrobial properties and promising antibiofilm activity, as well as good radical scavenging potential and low cytotoxicity.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Energy & Fuels
Chia Hau Lee, Norfadilah Hamdan, Luo Ing Ling, Syie Luing Wong, Bemgba Bevan Nyakuma, Shing Ching Khoo, Heeravathy Ramachandran, Haryati Jamaluddin, Keng Yinn Wong, Ting Hun Lee
Summary: This study investigated the antioxidant and antidiabetic properties of soursop leaf biomass hydrolysates (SLH). The results showed that flavourzyme-generated SLH had the highest peptide content compared to alcalase-and trypsin-generated SLH. SLH demonstrated strong antioxidant and antidiabetic activities, with 14 identified bioactive peptides, two of which showed high binding probability to alpha-glucosidase and alpha-amylase. These findings suggest that SLH could be used for diabetes prevention.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Energy & Fuels
Michael Lubwama, Vianney Andrew Yiga, Harriet Nalubega Lubwama, Ivan Ssempijja, Joseph Kihedu
Summary: Firewood and charcoal are the primary fuel sources for cooking in sub-Saharan Africa. This study examined the performance and emissions characteristics of different species of firewood and charcoal. The results showed that charcoal had higher thermal efficiency and lower indoor CO emissions compared to firewood. However, both firewood and charcoal exceeded the recommended CO emission levels. CO2 emissions were the highest contributor to greenhouse gas emissions. Proper ventilation is necessary when using firewood and charcoal for combustion.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Materials Science, Multidisciplinary
Reham Z. Hamza, Shaden E. Al-Motaani, Tarek Al-Talhi
Summary: The study found that the extract of Combretum molle has significant antioxidant effects on oxidative stress in diabetic animal tissues and helps repair changes in the skin layers, promising great improvements for diabetic patients with foot ulcers.
Article
Immunology
Anouar Feriani, Meriam Tir, Afoua Mufti, Ana Maria Gomez Caravaca, Maria del Mar Contreras, Amani Taamalli, Antonio Segura Carretero, Nouf Aldawood, Saber Nahdi, Saleh Alwasel, Abdel Halim Harrath, Nizar Tlili
Summary: This study aimed to investigate the phytochemical variability among Schinus terebinthifolius (STE) and Schinus molle (SME) fruit extracts, showing their potential application in food and pharmaceutical industries against ROS-induced damage.
INFLAMMOPHARMACOLOGY
(2021)
Article
Entomology
Nanxia Fu, Tobias Becker, Wolfgang Brandt, Maritta Kunert, Antje Burse, Wilhelm Boland
Summary: The study identified CYP347W1 is involved in the biosynthesis of a defense compound in Chrysomelina beetles. Knocking down CYP347W1 results in decreased concentration of isoxazolin-5-one glucoside ester and increased concentration of isoxazolin-5-one glucoside.
Article
Biochemistry & Molecular Biology
Shuting Hu, James E. Simon, Mingfu Wang, Yizhen Wu, Yumin Huang, Qingli Wu
Summary: Kinkeliba, a popular bush tea in West African countries, has been found to have potential benefits for skin health. The extract from its leaves can improve cell survival rate and reduce skin inflammation caused by UV radiation. The extract also shows inhibitory effects on cellular reactive oxygen species and nitrotyrosine levels. Furthermore, topical application of the kinkeliba leaf extract gel can reduce skin inflammation and improve skin barrier function.
Article
Chemistry, Applied
Adjima Bougma, Aminata Sere, Bazoin Sylvain Raoul Bazie, Hassane Sangare, Judicael Thomas Ouilly, Imael Henri Nestor Bassole
Summary: Combretum collinum, Combretum micranthum, Combretum nigricans, and Combretum niorense are unconventional seed oils abundant in the African savannah. This study quantified the compositions of these seed oils in terms of proximate, mineral, amino acid, fatty acid, and triacylglycerol content, as well as investigated their oxidative and physicochemical properties. The results showed that these seed oils have good chemical composition and physicochemical properties, making them suitable for various applications in both food and non-food industries.
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
(2021)
Article
Pharmacology & Pharmacy
Khaidem Devika Chanu, Nanaocha Sharma, Vimi Kshetrimayum, Sushil Kumar Chaudhary, Suparna Ghosh, Pallab Kanti Haldar, Pulok K. Mukherjee
Summary: This study evaluates the antidiabetic capacity of the Ageratina adenophora hydroalcoholic (AAHY) extract in streptozotocin-nicotinamide (STZ-NA) induced diabetic Wistar albino rats. The results show that the AAHY extract has a significant blood glucose lowering capacity and inhibitory activities on enzymes related to diabetes. The study provides scientific support for the utilization of A. adenophora in treating type 2 diabetes, but further research is needed for efficacy and safety assessment in humans.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Muddatstsir Idris, Edwin Risky Sukandar, Adi Setyo Purnomo, Fahimah Martak, Sri Fatmawati
Summary: This study investigated the chemical composition and bioactivities of R. tomentosa leaf extracts. The methanolic extract showed the highest total phenolic and flavonoid contents, as well as strong antioxidant and cytotoxic activities. It also exhibited inhibitory effects on α-glucosidase and α-amylase, and reduced blood glucose levels in STZ-induced diabetic rats.
