Journal
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Volume 8, Issue 3, Pages 1052-1067Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2008.304
Keywords
nanoparticles; nanomaterials; fluorescence; luminescence; immunoassay; bioimaging; DNA; biosensors; microarrays; up-converting phosphors
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Funding
- NIEHS NIH HHS [5P42ES04699] Funding Source: Medline
- NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [P42ES004699] Funding Source: NIH RePORTER
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Recently different types of fluorescent nanoparticles and other nanostructures have been promoted as alternatives for the fluorescent organic dyes that are traditionally used in biotechnology. Quantum dots, dye-doped polymer and silica particles have found many applications in biochemical protocols and are extensively discussed in the literature. Nanostructures based on inorganic phosphors (nanophosphors) are a new emerging class of materials with unique properties that make them very attractive for bio-application. Some results for the successful application of nanophosphors in biochemical applications have been reported. In this review we summarize the types of materials, their properties that are relevant to bio-applications, and the current status of their implementation in biotechnology.
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