4.1 Review

Advances in nonlinear optical microscopy for biophotonics

Journal

JOURNAL OF NANOPHOTONICS
Volume 12, Issue 3, Pages -

Publisher

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.JNP.12.033007

Keywords

nonlinear optical microscopy; biophotonics; stimulated Raman scatting; coherent anti-Stokes Raman scattering; two-photon excited fluorescence; second harmonic generation; sum frequency generation

Funding

  1. National Natural Science Foundation of China [91436102, 11374353, 11474141, 51401239, 11704058]
  2. Fundamental Research Funds for the Central Universities in USTB
  3. National Basic Research Program of China [2016YFA0200802]

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This article reviews recent advances in nonlinear optical microscopy for biophotonics, including stimulated Raman scattering (SRS), coherent anti-Stokes Raman scattering (CARS), two-photon excited fluorescence (TPEF), second harmonic generation (SHG), and sum frequency generation (SFG). We first introduce the principles and applications of SRS, CARS, TPEF, SHG, and SFG and their individual applications for biophotonics. We then introduce the combination of SRS, CARS, TPEF, SHG, and SFG microscopy for biophotonics. Our review not only summarizes the recent advances in nonlinear optical microscopy but also can deepen the understanding of the combination of these types of nonlinear optical microscopy for biophotonics. (C) 2018 Society of Photo-Optical Instrumentation Engineers (SPIE)

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