Biomarkers of nanomaterial exposure and effect: current status

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

(2013) Changhui Fu et al.   BIOMATERIALS

The effect of primary particle size on biodistribution of inhaled gold nano-agglomerates

(2013) Suresh K. Balasubramanian et al.   BIOMATERIALS

Cardiovascular Toxicity of Different Sizes Amorphous Silica Nanoparticles in Rats After Intratracheal Instillation

(2013) Zhongjun Du et al.   Cardiovascular Toxicology

Toxicity assessment of manganese oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral exposure

(2013) Shailendra Pratap Singh et al.   JOURNAL OF APPLIED TOXICOLOGY

Cytotoxic, genotoxic and the hemolytic effect of titanium dioxide (TiO2) nanoparticles on human erythrocyte and lymphocyte cellsin vitro

(2013) Manosij Ghosh et al.   JOURNAL OF APPLIED TOXICOLOGY

Time-Course Effects of Intravenously Administrated Silica Nanoparticles on Blood Coagulation and Endothelial Function in Rats

(2013) Xin Liu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Multiple cytotoxic and genotoxic effects induced in vitro by differently shaped copper oxide nanomaterials

(2013) Sebastiano Di Bucchianico et al.   MUTAGENESIS

Novel lanthanide-labeled metal oxide nanoparticles improve the measurement of in vivo clearance and translocation

(2013) Aamir D Abid et al.   Particle and Fibre Toxicology

Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration

(2013) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes

(2013) Ana M. Tavares et al.   TOXICOLOGY IN VITRO

Studies of single-walled carbon nanotubes-induced hepatotoxicity by NMR-based metabonomics of rat blood plasma and liver extracts

(2013) Bencheng Lin et al.   Nanoscale Research Letters

Occupational Nanosafety Considerations for Carbon Nanotubes and Carbon Nanofibers

(2012) Vincent Castranova et al.   ACCOUNTS OF CHEMICAL RESEARCH

Distribution, Elimination, and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-Day Oral Exposure

(2012) Meike van der Zande et al.   ACS Nano

Short- and long-term changes in blood miRNA levels after nanogold injection in rats—potential biomarkers of nanoparticle exposure

(2012) Wee-Siong Chew et al.   BIOMARKERS

Genotoxicity of poly(propylene imine) dendrimers

(2012) Barbara Ziemba et al.   BIOPOLYMERS

Recent progress in studies of metallic nickel and nickel-based nanoparticles’ genotoxicity and carcinogenicity

(2012) Ruth Magaye et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Oxidative stress and inflammatory responses of rat following acute inhalation exposure to iron oxide nanoparticles

(2012) A Srinivas et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Impairment of Coronary Arteriolar Endothelium-Dependent Dilation after Multi-Walled Carbon Nanotube Inhalation: A Time-Course Study

(2012) Phoebe Stapleton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanoparticulate silver increases uric acid and allantoin excretion in rats, as identified by metabolomics

(2012) Niels Hadrup et al.   JOURNAL OF APPLIED TOXICOLOGY

The chronic spleen injury of mice following long-term exposure to titanium dioxide nanoparticles

(2012) Xuezi Sang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice

(2012) Ming-Fen Song et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Human Biomonitoring of Engineered Nanoparticles: An Appraisal of Critical Issues and Potential Biomarkers

(2012) Enrico Bergamaschi   Journal of Nanomaterials

Epidemiological study of health hazards among workers handling engineered nanomaterials

(2012) Saou-Hsing Liou et al.   JOURNAL OF NANOPARTICLE RESEARCH

Genotoxicity of TiO2 anatase nanoparticles in B6C3F1 male mice evaluated using Pig-a and flow cytometric micronucleus assays

(2012) Rakhshinda Sadiq et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not

(2012) Thomas R. Downs et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vitro and in vivo genotoxicity of silver nanoparticles

(2012) Manosij Ghosh et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Nanoparticles from photocopiers induce oxidative stress and upper respiratory tract inflammation in healthy volunteers

(2012) Madhu Khatri et al.   Nanotoxicology

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Comparison of dermal absorption of zinc from different sunscreen formulations and differing UV exposure based on stable isotope tracing

(2012) Brian Gulson et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Characterization of coal fly ash nanoparticles and induced oxidative DNA damage in human peripheral blood mononuclear cells

(2012) Sourabh Dwivedi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Distribution and Systemic Effects of Intranasally Administered 25 nm Silver Nanoparticles in Adult Mice

(2012) Mary Beth Genter et al.   TOXICOLOGIC PATHOLOGY

Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis

(2012) Julie A. Bourdon et al.   TOXICOLOGICAL SCIENCES

Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure

(2012) Julie A. Bourdon et al.   TOXICOLOGY

Effects of SiC nanoparticles orally administered in a rat model: Biodistribution, toxicity and elemental composition changes in feces and organs

(2012) Omar Lozano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Comparative study of genotoxicity and tissue distribution of nano and micron sized iron oxide in rats after acute oral treatment

(2012) Shailendra Pratap Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cyto and genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells

(2012) Iêda Maria Martinez Paino et al.   TOXICOLOGY LETTERS

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

(2012) Kazuma Higashisaka et al.   Nanoscale Research Letters

Bioavailability and Toxicokinetics of citrate-coated silver nanoparticles in rats

(2011) Kwangsik Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Cytotoxicity and genotoxicity of titanium dioxide nanoparticles in UVA-irradiated normal peripheral blood lymphocytes

(2011) Su Jin Kang et al.   DRUG AND CHEMICAL TOXICOLOGY

Bio-distribution andin vivoantioxidant effects of cerium oxide nanoparticles in mice

(2011) Suzanne Marie Hirst et al.   ENVIRONMENTAL TOXICOLOGY

Gold nanoparticle-mediated gene delivery induces widespread changes in the expression of innate immunity genes

(2011) E-Y Kim et al.   GENE THERAPY

Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats

(2011) Siva Krishna Nalabotu et al.   International Journal of Nanomedicine

Biological monitoring versus air monitoring strategies in assessing environmental–occupational exposure

(2011) Marek Jakubowski   JOURNAL OF ENVIRONMENTAL MONITORING

Metabonomic Studies of Biochemical Changes in the Serum of Rats by Intratracheally Instilled TiO2 Nanoparticles

(2011) Meng Tang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Feasibility of Biomarker Studies for Engineered Nanoparticles

(2011) Ning Li et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Nanomaterials and Worker Health

(2011) Paul A. Schulte et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Characterization of synthesized silver nanoparticles and assessment of its genotoxicity potentials using the alkaline comet assay

(2011) Natesan A.L. Flower et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxicity of inhaled nanosized TiO2 in mice

(2011) Hanna K. Lindberg et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke

(2011) Jon N Marsh et al.   Nanomedicine

A health surveillance case study on workers who manufacture silver nanomaterials

(2011) Ji Hyun Lee et al.   Nanotoxicology

Airborne Engineered Nanoparticles: Potential Risks and Monitoring Challenges for Assessing their Impacts on Children

(2011) G. Biskos et al.   Paediatric Respiratory Reviews

Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate

(2011) Katrin Loeschner et al.   Particle and Fibre Toxicology

Acute inhalation toxicity of cerium oxide nanoparticles in rats

(2011) A. Srinivas et al.   TOXICOLOGY LETTERS

The use of biomarkers in occupational health research, practice, and policy

(2011) P.A. Schulte et al.   TOXICOLOGY LETTERS

Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials

(2010) Kazuma Higashisaka et al.   BIOMATERIALS

Early biomarkers of cadmium exposure and nephrotoxicity

(2010) Walter C. Prozialeck et al.   BIOMETALS

Genotoxicity of titanium dioxide (TiO2) nanoparticles at two trophic levels: Plant and human lymphocytes

(2010) Manosij Ghosh et al.   CHEMOSPHERE

Repeated-dose toxicity and inflammatory responses in mice by oral administration of silver nanoparticles

(2010) Eun-Jung Park et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The effect of magnetic nanoparticles of Fe3O4 on immune function in normal ICR mice

(2010) Baoan Chen   International Journal of Nanomedicine

Dose Dependent In Vivo Metabolic Characteristics of Titanium Dioxide Nanoparticles

(2010) Meng Tang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Nanoparticle Emission Assessment Technique (NEAT) for the Identification and Measurement of Potential Inhalation Exposure to Engineered Nanomaterials—Part B: Results from 12 Field Studies

(2010) M. Methner et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE

An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids

(2010) Jianghua Feng et al.   NANOTECHNOLOGY

NMR-based metabonomic study of the sub-acute toxicity of titanium dioxide nanoparticles in rats after oral administration

(2010) Qian Bu et al.   NANOTECHNOLOGY

Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation

(2010) Xiao He et al.   NANOTECHNOLOGY

Integrated metabonomics analysis of the size-response relationship of silica nanoparticles-induced toxicity in mice

(2010) Xiaoyan Lu et al.   NANOTECHNOLOGY

Rapid translocation of nanoparticles from the lung airspaces to the body

(2010) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

Molecular circuits of solid tumors: prognostic and predictive tools for bedside use

(2010) Charles Ferté et al.   Nature Reviews Clinical Oncology

Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes

(2010) Robert R Mercer et al.   Particle and Fibre Toxicology

Evaluation of oxidative stress and anti-oxidant status in rat serum following exposure of carbon nanotubes

(2010) A. Rama Narsimha Reddy et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Small Amounts of Zinc from Zinc Oxide Particles in Sunscreens Applied Outdoors Are Absorbed through Human Skin

(2010) Brian Gulson et al.   TOXICOLOGICAL SCIENCES

Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice

(2010) Eun-Jung Park et al.   TOXICOLOGY

Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles

(2010) Wenhua Song et al.   TOXICOLOGY LETTERS

Dose-dependent in-vivo toxicity assessment of silver nanoparticle in Wistar rats

(2010) Dhermendra K Tiwari et al.   TOXICOLOGY MECHANISMS AND METHODS

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

(2009) B. Trouiller et al.   CANCER RESEARCH

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

In vivo genotoxicity assessment of aluminium oxide nanomaterials in rat peripheral blood cells using the comet assay and micronucleus test

(2009) A. Balasubramanyam et al.   MUTAGENESIS

Using carbon nanotubes to induce micronuclei and double strand breaks of the DNA in human cells

(2009) Jelena Cveticanin et al.   NANOTECHNOLOGY

Induction of chronic inflammation in mice treated with titanium dioxide nanoparticles by intratracheal instillation

(2009) Eun-Jung Park et al.   TOXICOLOGY

Tissue distribution of 20nm, 100nm and 1000nm fluorescent polystyrene latex nanospheres following acute systemic or acute and repeat airway exposure in the rat

(2009) Katherine Sarlo et al.   TOXICOLOGY

Medical surveillance, exposure registries, and epidemiologic research for workers exposed to nanomaterials

(2009) Douglas B. Trout et al.   TOXICOLOGY

Pulmonary toxicity and kinetic study of Cy5.5-conjugated superparamagnetic iron oxide nanoparticles by optical imaging

(2009) Wan-Seob Cho et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Biomonitoring for occupational health risk assessment (BOHRA)☆

(2009) Maurizio Manno et al.   TOXICOLOGY LETTERS

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes

(2008) Su Jin Kang et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Proteomics-based diagnosis of chronic obstructive pulmonary disease: the hunt for new markers

(2008) Begona Casado et al.   Expert Review of Proteomics

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

(2008) Ning Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Twenty-Eight-Day Oral Toxicity, Genotoxicity, and Gender-Related Tissue Distribution of Silver Nanoparticles in Sprague-Dawley Rats

(2008) Yong Soon Kim et al.   INHALATION TOXICOLOGY

Airborne Particulate Matter and Human Health: Toxicological Assessment and Importance of Size and Composition of Particles for Oxidative Damage and Carcinogenic Mechanisms

(2008) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Comparative genotoxicity of cobalt nanoparticles and ions on human peripheral leukocytes in vitro

(2008) R. Colognato et al.   MUTAGENESIS

Environmental and occupational biomonitoring using the Comet assay

(2008) M VALVERDE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Cross-Talk between Lung and Systemic Circulation during Carbon Nanotube Respiratory Exposure. Potential Biomarkers

(2008) Aaron Erdely et al.   NANO LETTERS

Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus?

(2008) A.A. Shvedova et al.   PHARMACOLOGY & THERAPEUTICS

Biodistribution of 1.4- and 18-nm Gold Particles in Rats

(2008) Manuela Semmler-Behnke et al.   Small

Subchronic Inhalation Toxicity of Silver Nanoparticles

(2008) Jae Hyuck Sung et al.   TOXICOLOGICAL SCIENCES

Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: A rapid in vivo screening method for nanotoxicity

(2008) Ronghui Lei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Experimental exposure to wood smoke: effects on airway inflammation and oxidative stress

(2007) L Barregard et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE