Journal
JOURNAL OF NANOPARTICLE RESEARCH
Volume 13, Issue 5, Pages 2073-2079Publisher
SPRINGER
DOI: 10.1007/s11051-010-9962-x
Keywords
Biotransformations; Molecularly imprinted polymer (MIP); Nanotraps; Lipase; Nanobiotechnology
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The nanoparticle comprises a superparamagnetic iron oxide nanoparticle core conjugated with trimethoxylsilyl propylmethacrylate (TMSPM) and methacryloylamido serine (MASE), methacryloylamido histidine (MAH), methacryloylamido glutamic acid (MAGA) monomers, and p-nitrophenyl palmitate (p-NPP) which is a substrate of lipase as a template molecule, which enables the creation of lipase active region. The resulting hybrid superparamagnetic nanotraps are magnetically separable, highly active, and stable under harsh conditions. In this study, the advantages of high selectivity of molecular imprinting technique have used to get mimic lipase for the synthesis of methyl jasmonate and methyl oleate.
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