Network analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms

Pharmacogenetic predictor of extrapyramidal symptoms induced by antipsychotics: Multilocus interaction in the mTOR pathway

(2015) S. Mas et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Perspective: Retreat from the radical

(2014) Stephen R. Marder   NATURE

Perspective: Revealing molecular secrets

(2014) Steven E. Hyman   NATURE

Antipsychotics Activate mTORC1-Dependent Translation to Enhance Neuronal Morphological Complexity

(2014) H. Bowling et al.   Science Signaling

Second-Generation Antipsychotics and Extrapyramidal Adverse Effects

(2014) Nevena Divac et al.   Biomed Research International

Potential Molecular and Cellular Mechanism of Psychotropic Drugs

(2014) Myoung Suk Seo et al.   Clinical Psychopharmacology and Neuroscience

Novel drug-regulated transcriptional networks in brain reveal pharmacological properties of psychotropic drugs

(2013) Michal Korostynski et al.   BMC GENOMICS

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells

(2013) Soon Young Shin et al.   CARCINOGENESIS

New insights into Notch1 regulation of the PI3K–AKT–mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

(2013) Eric C. Hales et al.   CELLULAR SIGNALLING

Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1

(2013) Alessandra Bonito-Oliva et al.   NEUROPHARMACOLOGY

CYP2D6 poor metabolizer status might be associated with better response to risperidone treatment

(2013) Berta Almoguera et al.   Pharmacogenetics and Genomics

Pharmacogenetics of clinical response to risperidone

(2013) Adrián LLerena et al.   PHARMACOGENOMICS

Functional analysis of gene expression in risperidone treated cells provide new insights in molecular mechanism and new candidate genes for pharmacogenetic studies

(2012) Sergi Mas et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels

(2012) Olga Carretón et al.   EXPERIMENTAL NEUROLOGY

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

(2011) James J. Crowley et al.   MAMMALIAN GENOME

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

(2011) Albert Giralt et al.   Molecular Neurodegeneration

Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

(2011) Emmanuel Valjent et al.   NEUROPSYCHOPHARMACOLOGY

Searching for functional SNPs or rare variants in exonic regions of DRD3 in risperidone-treated patients

(2010) Patricia Gassó et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Functional genomics and networks: new approaches in the extraction of complex gene modules

(2010) Pablo Minguez et al.   Expert Review of Proteomics

Signaling Pathways Leading to Phosphorylation of Akt and GSK-3  by Activation of Cloned Human and Rat Cerebral D2 and D3 Receptors

(2010) C. Mannoury la Cour et al.   MOLECULAR PHARMACOLOGY

Intuitive pharmacogenetics: spontaneous risperidone dosage is related to CYP2D6, CYP3A5 and ABCB1 genotypes

(2010) S Mas et al.   PHARMACOGENOMICS JOURNAL

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Identification of cAMP-Dependent Kinase as a Third in Vivo Ribosomal Protein S6 Kinase in Pancreatic β-Cells

(2009) Claire E.J. Moore et al.   JOURNAL OF MOLECULAR BIOLOGY

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

Convergent Functional Genomics: what we have learned and can learn about genes, pathways and mechanisms

(2009) Alexander B Niculescu et al.   NEUROPSYCHOPHARMACOLOGY

SNOW, a web-based tool for the statistical analysis of protein–protein interaction networks

(2009) Pablo Minguez et al.   NUCLEIC ACIDS RESEARCH

A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms

(2009) P Gassó et al.   PHARMACOGENOMICS JOURNAL

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

CYP2D6*3, *4, *5 AND *6 POLYMORPHISMS AND ANTIPSYCHOTIC-INDUCED EXTRAPYRAMIDAL SIDE-EFFECTS IN PATIENTS RECEIVING ANTIPSYCHOTIC THERAPY

(2008) Anna Crescenti et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY