Genetic variants inSLC22A17 and SLC22A7are associated with anthracycline-induced cardiotoxicity in children

Development of a broad-based ADME panel for use in pharmacogenomic studies

(2014) Andrew MK Brown et al.   PHARMACOGENOMICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Validation of variants inSLC28A3andUGT1A6as genetic markers predictive of anthracycline-induced cardiotoxicity in children

(2013) H. Visscher et al.   PEDIATRIC BLOOD & CANCER

Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization

(2012) Allan D Heibein et al.   BMC CANCER

Single-Nucleotide Polymorphisms in Aldo-Keto and Carbonyl Reductase Genes Are Not Associated with Acute Cardiotoxicity after Daunorubicin Chemotherapy

(2012) J. M. Lubieniecka et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal

(2012) Paiboon Jungsuwadee et al.   Pharmacogenetics and Genomics

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Pharmacogenomic Prediction of Anthracycline-Induced Cardiotoxicity in Children

(2011) Henk Visscher et al.   JOURNAL OF CLINICAL ONCOLOGY

Anthracycline-Related Cardiomyopathy After Childhood Cancer: Role of Polymorphisms in Carbonyl Reductase Genes—A Report From the Children's Oncology Group

(2011) Javier G. Blanco et al.   JOURNAL OF CLINICAL ONCOLOGY

Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition

(2011) Pedro Cano-Soldado et al.   MEDICINAL RESEARCH REVIEWS

Expression and analysis of two novel rat organic cation transporter homologs, SLC22A17 and SLC22A23

(2011) Katie M. Bennett et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cardiac Function in 5-Year Survivors of Childhood Cancer

(2010) Helena J. van der Pal et al.   ARCHIVES OF INTERNAL MEDICINE

Role of Cancer Treatment in Long-Term Overall and Cardiovascular Mortality After Childhood Cancer

(2010) Markhaba Tukenova et al.   JOURNAL OF CLINICAL ONCOLOGY

Naturally Occurring Variants of Human Aldo-Keto Reductases with Reduced In Vitro Metabolism of Daunorubicin and Doxorubicin

(2010) O. S. Bains et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Drug transporter pharmacogenetics in nucleoside-based therapies

(2010) Ekaitz Errasti-Murugarren et al.   PHARMACOGENOMICS

Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity

(2009) Yunfang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

New Developments in Anthracycline-Induced Cardiotoxicity

(2009) A. Mordente et al.   CURRENT MEDICINAL CHEMISTRY

Analysis of the host pharmacogenetic background for prediction of outcome and toxicity in diffuse large B-cell lymphoma treated with R-CHOP21

(2009) D Rossi et al.   LEUKEMIA

Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood

(2009) Vladan Rajić et al.   LEUKEMIA & LYMPHOMA

Adverse drug reaction active surveillance: developing a national network in Canada's children's hospitals

(2009) BC Carleton et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Application of principal component analysis to pharmacogenomic studies in Canada

(2009) H Visscher et al.   PHARMACOGENOMICS JOURNAL

Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity

(2008) Jinping Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genetic polymorphisms in the carbonyl reductase 3 geneCBR3 and the NAD(P)H:quinone oxidoreductase 1 geneNQO1 in patients who developed anthracycline-related congestive heart failure after childhood cancer

(2008) Javier G. Blanco et al.   CANCER

A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms

(2008) Xiaoyi Gao et al.   GENETIC EPIDEMIOLOGY

Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters

(2008) M. Okabe et al.   MOLECULAR CANCER THERAPEUTICS

Organic Anion Transporter 2 (SLC22A7) Is a Facilitative Transporter of cGMP

(2008) C. D. Cropp et al.   MOLECULAR PHARMACOLOGY