Article
Computer Science, Information Systems
Raushan Myrzashova, Saeed Hamood Alsamhi, Alexey V. Shvetsov, Ammar Hawbani, Xi Wei
Summary: Recently, innovations in the Internet of Medical Things (IoMT), information and communication technologies, and machine learning (ML) have enabled smart healthcare. Federated learning (FL) overcomes the challenges of centralized data storage and provides high-level security and privacy for smart healthcare. Combining blockchain and FL can further enhance the competency of healthcare by managing data in a decentralized manner and utilizing dispersed clinical data fully.
IEEE INTERNET OF THINGS JOURNAL
(2023)
Review
Public, Environmental & Occupational Health
Ingridy M. P. Barbalho, Felipe Fernandes, Daniele M. S. Barros, Jailton C. Paiva, Jorge Henriques, Antonio H. F. Morais, Karilany D. Coutinho, Giliate C. Coelho Neto, Arthur Chioro, Ricardo A. M. Valentim
Summary: This paper presents an audit of the main approaches used for Electronic Health Records (EHR) development in Brazil, discussing prospects, challenges, and existing gaps. The analysis highlights the importance of interoperability, data security, and defined development methodologies.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Telecommunications
Leonardo B. Furstenau, Pedro Leivas, Michele Kremer Sott, Michael S. Dohan, Jose Ricardo Lopez-Robles, Manuel J. Cobo, Nicola Luigi Bragazzi, Kim-Kwang Raymond Choo
Summary: This study used bibliometric performance and network analysis to examine the strategic themes, thematic evolution structure, main challenges, and opportunities of big data in the healthcare sector. The analysis revealed the significant role of big data in enhancing decision-making, diagnosis, and disease prediction accuracy.
DIGITAL COMMUNICATIONS AND NETWORKS
(2023)
Article
Health Care Sciences & Services
Aamir Ahmed, Norman R. Williams
Summary: Pakistan faces significant challenges in providing healthcare due to inconsistent policymaking, rising expenditure, and population growth. Clinical trials are crucial for finding population-specific, cost-effective treatments. Repurposing medicines offers a particularly promising approach as it utilizes affordable drugs that are already widely available.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Public, Environmental & Occupational Health
Maram Gamal Katoue, Arcadio A. Cerda, Leidy Y. Garcia, Mihajlo Jakovljevic
Summary: This review provides an overview of the development efforts in the health systems of Middle Eastern and North African countries. It highlights progress, challenges, and future opportunities for achieving responsive and efficient health systems. The review identifies key areas for improvement and provides recommendations for supporting health system reforms.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medical Informatics
Daniel M. Walker, Willi L. Tarver, Pallavi Jonnalagadda, Lorin Ranbom, Eric W. Ford, Saurabh Rahurkar
Summary: This study aimed to identify current challenges and opportunities to advancing interoperability across stakeholders. Primary data were collected through qualitative, semistructured interviews with stakeholders. The findings illuminate themes related to challenges and opportunities for interoperability that align with technological, organizational, and environmental domains.
JMIR MEDICAL INFORMATICS
(2023)
Article
Computer Science, Artificial Intelligence
Ibrar Yaqoob, Khaled Salah, Raja Jayaraman, Yousof Al-Hammadi
Summary: Blockchain technology has the potential to significantly revolutionize healthcare data management systems, bringing innovation and improvements. However, the adoption of blockchain technology also faces challenges that require further research and exploration.
NEURAL COMPUTING & APPLICATIONS
(2022)
Article
Computer Science, Information Systems
Jennifer C. Gander, Mahesh Maiyani, Larissa L. White, Andrew T. Sterrett, Brianna Guney, Pamala A. Pawloski, Teri DeFor, YuanYuan Olsen, Benjamin A. Rybicki, Christine Neslund-Dudas, Darsheen Sheth, Richard Krajenta, Devaki Purushothaman, Stacey Honda, Cyndee Yonehara, Katrina A. B. Goddard, Yolanda K. Prado, Habibul Ahsan, Muhammad G. Kibriya, Briseis Aschebrook-Kilfoy, Chun-Hung Chan, Sarah Hague, Christina L. Clarke, Brooke Thompson, Jennifer Sawyer, Mia M. Gaudet, Heather Spencer Feigelson
Summary: This study developed an algorithm using electronic medical records to identify cancer cases not captured in tumor registries, and its performance was validated in multiple integrated healthcare systems. The algorithm can identify cancer cases regardless of when the diagnosis occurred and is of great importance for cancer care research and quality improvement projects.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2022)
Review
Medicine, General & Internal
Jia Zhong, Jun Zhang, Honghao Fang, Larry Liu, Jipan Xie, Eric Wu
Summary: Various real-world data sources have emerged in China, aiming to generate real-world evidence for clinical and regulatory decision-making. However, there are significant barriers, including inconsistencies in terminology, non-standardised coding practices, lack of longitudinal data, and limited access and sharing of real-world data. To overcome these barriers and generate high-quality real-world data, collaborative and synergistic research networks involving multiple stakeholders are crucial.
Review
Computer Science, Artificial Intelligence
Ismail Keshta, Ammar Odeh
Summary: Electronic Medical Records (EMRs) offer many benefits to healthcare, but concerns about privacy and security have hindered adoption. Safeguarding sensitive health data at separate locations is a major challenge. This review identifies healthcare organizations' privacy and security concerns and explores potential solutions.
EGYPTIAN INFORMATICS JOURNAL
(2021)
Review
Materials Science, Multidisciplinary
Max Weston, Shu Geng, Rona Chandrawati
Summary: Food sensors have been developed for quality monitoring and contaminant detection to improve food management. However, challenges such as the complexity of food samples, sensor design, and signal processing need to be addressed for successful translation into commercial products.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Review
Statistics & Probability
Maryam Tayefi, Phuong Ngo, Taridzo Chomutare, Hercules Dalianis, Elisa Salvi, Andrius Budrionis, Fred Godtliebsen
Summary: Electronic health records contain valuable information and analyzing unstructured data from clinical text and images is complex. Challenges include data quality, privacy issues, and explaining machine learning results. Potential solutions include developing synthetic data generation methods and advancing privacy-preserving techniques.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL STATISTICS
(2021)
Article
Computer Science, Artificial Intelligence
S. G. Shivaprasad Yadav, Loshma Gunisetti, Shirin Bhanu Koduri, Thomas Scaria, Anita Dixit, S. Lokesh
Summary: Blockchain technology can create a distributed and decentralized ecosystem in the healthcare sector, improving the quality of electronic medical records and providing patient-centric healthcare systems. This work sets the foundation for future studies on decentralized dynamic data interoperability and integrity checks.
Article
Computer Science, Information Systems
Dur-E-Maknoon Nisar, Rashid Amin, Noor-Ul-Huda Shah, Mohammed A. Al Ghamdi, Sultan H. Almotiri, Meshrif Alruily
Summary: Deep learning is widely used in healthcare for diagnosing and treating chronic diseases, reducing medical costs. Research summarizes and compares deep learning methods in different disease areas, discussing research opportunities and challenges.
Article
Behavioral Sciences
Yanan Zhao, Binbin Su, Dawei Zhu, Xiaolong Guan, Ruoxi Ding, Dan Guo, Feng Lu, Ping He
Summary: As the number of people diagnosed with autism spectrum disorder (ASD) continues to rise, it is important to understand the costs associated with the condition. This study analyzed the utilization and costs of medical services for individuals with ASD in Beijing over a five-year period. The findings revealed a significant economic burden for individuals with ASD and highlighted the need for improved care and accessibility to services across different age groups.
Article
Health Care Sciences & Services
Simon Walker, Aimee Fox, James Altunkaya, Tim Colbourn, Mike Drummond, Susan Griffin, Nils Gutacker, Paul Revill, Mark Sculpher
Summary: Policy evaluations often focus on short-term outcomes and fail to consider policy-relevant results, opportunity costs, and decision uncertainty. Challenges in evaluating policies can be addressed with methods from various disciplines, but careful consideration of decision requirements, evidence, and methods is necessary.
MEDICAL DECISION MAKING
(2022)
Article
Economics
Megan Perry-Duxbury, James Lomas, Miqdad Asaria, Pieter van Baal
Summary: This study adjusted the empirical estimates of the healthcare threshold and found that including future healthcare costs had relatively little impact on the threshold estimate, but it could have considerable effects on the cost effectiveness of some life-extending interventions.
Article
Business, Finance
Miqdad Asaria, Alistair McGuire, Andrew Street
Summary: There is a popular belief that expenditure on healthcare management is wasteful and detracts from patient care. However, there is little evidence to support this claim. A study on public sector hospitals in England found no association between the quantity of management and hospital performance, but higher-quality management was associated with better performance.
Article
Public, Environmental & Occupational Health
Ieva Skarda, Miqdad Asaria, Richard Cookson
Summary: We introduce a new framework that evaluates childhood policies from a cross-sectoral whole-lifetime perspective, considering impacts on health, wellbeing, and inequality. This framework estimates total lifetime benefits and public cost savings using lifecourse micro-simulation, and conducts cost-effectiveness analysis, policy targeting analysis, and distributional analysis of inequality impacts. Through an example of re-evaluating a training program for parents of children at risk of conduct disorder, we illustrate the practical application of this framework.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Infectious Diseases
M. Quaife, G. F. Medley, M. Jit, T. Drake, M. Asaria, P. van Baal, R. Baltussen, L. Bollinger, F. Bozzani, O. Brady, H. Broekhuizen, K. Chalkidou, Y-L Chi, D. W. Dowdy, S. Griffin, H. Haghparast-Bidgoli, T. Hallett, K. Hauck, T. D. Hollingsworth, C. F. McQuaid, N. A. Menzies, M. W. Merritt, A. Mirelman, A. Morton, F. J. Ruiz, M. Siapka, J. Skordis, F. Tediosi, P. Walker, R. G. White, P. Winskill, A. Vassall, G. B. Gomez
Summary: This article discusses how to consider health equity in disease transmission models and provides guidance on technical approaches, including specifying equity concepts, choosing evaluation frameworks, model structures, and data requirements.
Article
Public, Environmental & Occupational Health
Rajendra Kadel, James Allen, Oliver Darlington, Rebecca Masters, Brendan Collins, Joanna M. Charles, Miqdad Asaria, Mariana Dyakova, Mark Bellis, Richard Cookson
Summary: In Wales, there are significant inequalities in health and healthcare use between people living in more deprived neighborhoods and those living in less deprived neighborhoods. This results in an additional cost of £322 million per year to the NHS, with emergency inpatient admissions being the largest contributor. Targeted health promotion and early intervention policies for deprived communities could lead to substantial improvements in health and savings for the Welsh NHS.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Economics
Sakshi Mohan, Simon Walker, Freddie Sengooba, Elizabeth Ekirapa Kiracho, Chrispus Mayora, Aloysius Ssennyonjo, Candia Tom Aliti, Paul Revill
Summary: This study demonstrates the use of linear constrained optimization approach in designing a health benefits package (HBP) to maximize net disability adjusted life years (DALYs) averted given the constraints of the health system. It also shows how the approach can assess the marginal value of relaxing these constraints. The analysis for Uganda included 45 interventions in the HBP, resulting in 26.7 million net DALYs averted in the base scenario.
Article
Multidisciplinary Sciences
Liina Mansukoski, Bridget Lockyer, Amy Creaser, Jessica Sheringham, Laura Sheard, Philip Garnett, Tiffany Yang, Richard Cookson, Alexandra Albert, Shahid Islam, Robert Shore, Aiysha Khan, Simon Twite, Tania Dawson, Halima Iqbal, Ieva Skarda, Aase Villadsen, Miqdad Asaria, Jane West, Trevor Sheldon, John Wright, Maria Bryant
Summary: This article introduces the ActEarly research program in the UK, aiming to improve the health and well-being of children and families living in high poverty areas. The evaluation of the program will use the ENCOMPASS framework and theory-based mixed-methods approaches to investigate its impact on early life health and well-being outcomes, as well as the system changes it brings. The evaluation methods include fidelity investigation, exploration of intervention-outcome relationships, and assessment of potential long-term benefits.
Article
Medicine, General & Internal
Lindsay Forbes, Jo Armes, Shuja Shafi, Amran Mohamed, Reham Mustafa, Osman Dar, Tushna Vandrevala, Richard Amlot, Andrew Hayward, Miqdad Asaria, Tasneem Pirani, Dale Weston, Sunayana Shah, Alimuddin Zumla, Aftab Ala
Summary: This study aims to evaluate a culturally appropriate intervention to promote COVID-19 health protective measures among Black and South Asian communities in the UK. The study includes a focus group, a questionnaire study, and a qualitative study to assess the impact of the intervention and gather the views of participants and health professionals. Participants will be recruited through general practices and data collection will take place in the community.
Article
Allergy
Stefania Arasi, Ulugbek Nurmatov, Audrey Dunn-Galvin, Graham Roberts, Paul J. Turner, Sayantani B. Shinder, Ruchi Gupta, Philippe Eigenmann, Anna Nowak-Wegrzyn, Ignacio J. Ansotegui, Montserrat Fernandez Rivas, Stavros Petrou, Luciana K. Tanno, Marta Vazquez-Ortiz, Brian Vickery, Gary Wong, Montserrat Alvaro-Lozano, Miqdad Asaria, Philippe Begin, Martin Bozzola, Robert Boyle, Helen Brough, Victoria Cardona, R. Sharon Chinthrajah, Antonella Cianferoni, Antoine Deschildre, David Fleischer, Flavio Gazzani, Jennifer Gerdts, Marilena Giannetti, Matthew Greenhawt, Maria Antonieta Guzman, Elham Hossny, Paula Kauppi, Carla Jones, Francesco Lucidi, Olga Patricia Monge Ortega, Daniel Munblit, Antonella Muraro, Giovanni Pajno, Marcia Podesta, Pablo Rodriguez del Rio, Maria Said, Alexandra Santos, Marcus Shaker, Hania Szajewska, Carina Venter, Cristopher Warren, Tonya Winders, Motohiro Ebisawa, Alessandro Fiocchi
Summary: A global consensus has been achieved on the development of the DEFASE scoring system for the severity of food allergy, which considers the overall disease spectrum. Further validation and implementation in research settings and clinical practice are planned.
WORLD ALLERGY ORGANIZATION JOURNAL
(2023)
Article
Economics
Miqdad Asaria, Joan Costa-Font, Frank Cowell
Summary: In this study, we examine individuals' aversion to health and income inequality in the United Kingdom, Germany, and Italy, and explore the determinants of such aversion. We also investigate the impact of COVID-19 specific shocks on employment status, income, and health. Our findings reveal a significant increase in inequality aversion in both income and health domains, with higher aversion in the income domain. We further identify age, education, income, and risk appetite as factors affecting inequality aversion. Interestingly, individuals directly exposed to major health shocks during the pandemic exhibit lower aversion to both income and health inequality. Additionally, we find that those exposed to higher COVID-19 mortality risk and major health shocks experience significantly higher levels of inequality aversion.
SOCIAL CHOICE AND WELFARE
(2023)
Article
Health Care Sciences & Services
James E. Bennett, Theo Rashid, Alireza Zolfaghari, Yvonne Doyle, Esra Suel, Jonathan Pearson-Stuttard, Bethan Davies, Daniela Fecht, Emily S. Muller, Ricky S. Nathvani, Noemie Sportiche, Hima Iyathooray Daby, Eric Johnson, Guangquan Li, Seth Flaxman, Mireille B. Toledano, Miqdad Asaria, Majid Ezzati
Summary: This study investigated life expectancy change in London and its relationship with house prices. It found that life expectancy varied with house price changes in very small areas of London. Some areas experienced a decline in life expectancy, while others saw an increase. The study also found that life expectancy increased mainly in areas with high house prices or areas where house prices had grown the most.
LANCET REGIONAL HEALTH-EUROPE
(2023)
Review
Public, Environmental & Occupational Health
Zinia T. Nujum, Miqdad Asaria, Karishma Krishna Kurup, Malathi Mini, Sumit Mazumdar, Monal Daptardar, Harish Tiwari
Summary: Economic evaluations suggest that an optimal One Health (OH) approach to tackle rabies should incorporate mass dog vaccination, integrated bite case management, and a 1-week abbreviated intradermal rabies vaccine regimen in humans. Future evaluations should consider feasibility, costs, and outcomes across both human health and animal welfare sectors.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
(2023)
Article
Medicine, General & Internal
John S. Moin, Simone N. Vigod, Lesley Plumptre, Natalie Troke, Miqdad Asaria, Irene Papanicolas, Walter P. Wodchis, Shauna Brail, Geoff Anderson
Summary: This study compared rates of mental health service use during the pandemic to pre-pandemic rates and found that there were prolonged high rates of mental health use, particularly in female adolescents and young women. This highlights the need to better monitor and identify mental health outcomes associated with COVID-19 containment measures and to develop policies to address these concerns.
Article
Public, Environmental & Occupational Health
Aase Villadsen, Miqdad Asaria, Ieva Skarda, George B. Ploubidis, Mark Mon Williams, Eric John Brunner, Richard Cookson
Summary: Background disadvantage in early childhood is associated with worse health and educational outcomes in adolescence. This study examined the association between household income in early childhood and various outcomes at age 17, and found that lower income during childhood was strongly correlated with multiple adverse outcomes in adolescence. However, shifting children to a slightly higher income group had limited impact on improving outcomes.
LANCET PUBLIC HEALTH
(2023)