Investigation of Color in a Fusion Protein Using Advanced Analytical Techniques: Delineating Contributions from Oxidation Products and Process Related Impurities

Characterization of the Degradation Products of a Color-Changed Monoclonal Antibody: Tryptophan-Derived Chromophores

(2014) Yiming Li et al.   ANALYTICAL CHEMISTRY

Detection of Histidine Oxidation in a Monoclonal Immunoglobulin Gamma (IgG) 1 Antibody

(2014) Masato Amano et al.   ANALYTICAL CHEMISTRY

Recombinant Antibody Color Resulting from Advanced Glycation End Product Modifications

(2014) Margaret Butko et al.   ANALYTICAL CHEMISTRY

Effect of cell culture medium components on color of formulated monoclonal antibody drug substance

(2013) Natarajan Vijayasankaran et al.   BIOTECHNOLOGY PROGRESS

Hydroxocobalamin association during cell culture results in pink therapeutic proteins

(2013) Kenneth M Prentice et al.   mAbs

Brown drug substance color investigation in cell culture manufacturing using chemically defined media: A case study

(2013) Jianlin Xu et al.   PROCESS BIOCHEMISTRY

Effect of pH and Light on Aggregation and Conformation of an IgG1 mAb

(2012) Bruce D. Mason et al.   MOLECULAR PHARMACEUTICS

Role of Surface Exposed Tryptophan as Substrate Generators for the Antibody Catalyzed Water Oxidation Pathway

(2012) Alavattam Sreedhara et al.   MOLECULAR PHARMACEUTICS

N-Formylkynurenine as a Marker of High Light Stress in Photosynthesis

(2011) Tina M. Dreaden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIC resolution of an IgG1 with an oxidized Trp in a complementarity determining region

(2011) Daniel Boyd et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Photosensitizers Form in Histidine Buffer and Mediate the Photodegradation of a Monoclonal Antibody

(2011) Steven D. Stroop et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Opalescence of an IgG2 monoclonal antibody solution as it relates to liquid–liquid phase separation

(2011) Bruce D. Mason et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Crystal structure of human germline antibody 3-23/B3

(2011) Thomas J. Malia et al.   MOLECULAR IMMUNOLOGY

Site-Specific Tryptophan Oxidation Induced by Autocatalytic Reaction of Polysorbate 20 in Protein Formulation

(2011) Xanthe M. Lam et al.   PHARMACEUTICAL RESEARCH

A critical evaluation of self-interaction chromatography as a predictive tool for the assessment of protein–protein interactions in protein formulation development: A case study of a therapeutic monoclonal antibody

(2010) Virginie Le Brun et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Ultraviolet Spectroscopy as a Tool in Therapeutic Protein Development

(2010) Henryk Mach et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Singlet-oxygen-mediated amino acid and protein oxidation: Formation of tryptophan peroxides and decomposition products

(2009) Michelle Gracanin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Methionine, tryptophan, and histidine oxidation in a model protein, PTH: Mechanisms and stabilization

(2009) Junyan A. Ji et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Understanding and Modulating Opalescence and Viscosity in a Monoclonal Antibody Formulation

(2009) Branden A. Salinas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The dependence of luminous efficiency on chromatic adaptation

(2009) A. Stockman et al.   JOURNAL OF VISION

Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form

(2008) Pei Qi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES