Article
Chemistry, Physical
Tiago Fernandes, Sara Fateixa, Marta Ferro, Helena I. S. Nogueira, Ana L. Daniel-da-Silva, Tito Trindade
Summary: The use of dendrimers in the controlled synthesis of Ag:Au hybrid nanostructures enhances SERS sensitivity to organic pollutants. Dendrimers play a crucial role as multipurpose ligands in the formation of hybrid nanostructures, improving stability and sensitivity. Interparticle plasmonic coupling templated by dendrimer macromolecules contributes to the high SERS sensitivity of the hybrid nanostructures.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Kedong Gong, Robin Raffe Jones, Kejian Li, Guanjun Xu, Hanyun Cheng, Yiqing Feng, Ventsislav Kolev Valev, Liwu Zhang
Summary: The study developed a method to directly measure the pH of microdroplets using Surface Enhanced Raman Scattering technology. It establishes the relationship between microdroplet size and pH value, and showcases the potential application in environmental samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Cristina Gellini, Marina Macchiagodena, Marco Pagliai
Summary: The adsorption geometry of alizarin on silver nanoparticles was studied using density functional theory calculations, considering different charged species present in solution at different pH values. The results accurately reproduced the measured SERS spectra and elucidated the adsorption geometry of the dye on the silver substrate.
Article
Chemistry, Physical
Jianguo Wang, Songlin Yang, Yurong Cao, Yong-Hong Ye
Summary: A simple approach to fabricate large-scale optoplasmonic hybrid materials (OHMs) for high sensitivity surface-enhanced Raman spectroscopy (SERS) is proposed. The OHM consists of a metal film, a monolayer of nanoparticles (MFON), and a microsphere. The excited wavelength of the localized surface plasmon resonance in the MFON can be controlled by the size of the nanoparticles and an additional dielectric layer. Under specific conditions, Raman signals of low concentration methylene blue can be detected. Numerical simulations show that the OHM provides enhanced sensitivity compared to traditional plasmonic nanostructures.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Cell Biology
Sergey Dubkov, Aleksei Overchenko, Denis Novikov, Vasilii Kolmogorov, Lidiya Volkova, Petr Gorelkin, Alexander Erofeev, Yuri Parkhomenko
Summary: This study presents an original technique for fabricating silver-coated pipettes and explores their use in cell analysis through surface-enhanced Raman spectroscopy and scanning ion-conducting microscopy. The results demonstrate the potential of this method for molecular composition analysis of living cells.
Article
Chemistry, Physical
Vishakha Kaushik, Hardik L. Kagdada, Dheeraj K. Singh, Sachin Pathak
Summary: The study explores hybrid SERS substrates prepared by coating silver nanoparticles on graphene layers, utilizing both chemical and electromagnetic enhancement mechanisms for remarkable SERS intensities. The experiment and theory demonstrate substantial enhancement in electronic and vibrational properties of graphene fragments through interactions with small silver clusters, leading to enhanced G-band intensity. This research contributes to the understanding of mechanisms and the development of high-performance SERS substrates for sensing applications.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Analytical
Md Imran Hossain, Sitansu Sekhar Nanda, Sooheon Cho, Bom Lee, Bum Jun Kim, Jae-Young Choi, Dong Kee Yi
Summary: Surface-enhanced Raman spectroscopy (SERS) is an effective technique for label-free detection of biomolecules with enhanced sensitivity. In this study, we investigated the electrostatic interactions of bacterial samples with gold nanorods (AuNRs) and graphene, and established a voltage-gated 3D graphene functionalized with an AuNR-based device for SERS measurements. Our fabricated device provides a label-free, rapid, and reproducible analysis of bacterial samples based on the density of AuNRs when functionalizing flake-like 3D graphene, offering great potential for label-free bacteria sensing platforms.
Article
Chemistry, Multidisciplinary
Yanjun Yang, Chunyuan Song, Jingjing Zhang, Jie Chao, Hoang Mai Luong, Yiping Zhao, Lianhui Wang
Summary: This article introduces a surface-enhanced Raman scattering (SERS) sensor based on a functionalized multiple-armed tetrahedral DNA nanostructure, which is capable of detecting multiple nucleic acid and protein biomarkers related to lung cancer and has enhanced sensitivity. The sensor achieves enhanced Raman signals through DNA self-assembled gold nanoparticle clusters in multiplex detections.
Article
Spectroscopy
Soogeun Kim, Young Jin Kim, Ayoung Bang, Wansun Kim, Samjin Choi, Hee Joo Lee
Summary: The study investigated the impact of Raman excitation wavelengths on the surface-enhanced Raman spectroscopy (SERS) for the identification of nontuberculous mycobacteria (NTM). By comparing SERS spectra with three commonly used excitation wavelengths, it was found that NTM species could be distinguished with statistical differences. Utilizing principal components-linear discriminant analysis and leave-one-out cross validation, the study achieved identification accuracies for six NTM species using aromatic amino acid biomarkers at different excitation wavelengths.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Physical
Honghao Tian, Youjian Qin, Hongmei Liu, Tian Li, Yuting Li, Xiaohui Fang, Xinping Zhang
Summary: In this study, metal or alloy nanoparticles prepared by the Brust-Schiffrin method were used as inks in a ballpoint pen to handwrite SERS test strips on PTFE membranes. The PTFE membranes showed good lipophilicity and flexibility, allowing for good uniformity. The Au1Ag8 nanoparticles showed the best performance, with the ability to detect 10(-11)-M Rhodamine 6G dyes in a 10-mu L volume with an enhancement factor of 5.4x10(8). The SERS strips were successfully used to detect malachite green in aquaculture and fish tanks.
Article
Physics, Multidisciplinary
Xiao-Lei Zhang, Jie Zhang, Yuan Luo, Jia Ran
Summary: A two-dimensional surface-enhanced Raman scattering (SERS) substrate was fabricated by decorating carbon nanotube films with Ag nanoparticles via a simple and low-cost method. The Raman and SERS activity of the composites were investigated using rhodamine 6G as a probe molecule. The results showed that the SERS and electric field intensity increased with the size of Ag nanoparticles.
Article
Chemistry, Physical
Nazar Riswana Barveen, Tzyy-Jiann Wang, Ying-Yu Wang, Cheng-Yao Weng, Kai-Jiun Chen
Summary: The development of flexible and transparent detection platforms using surface-enhanced Raman spectroscopy is highly important for in-situ, real-time analysis. In this study, soft and ultra-thin substrates composed of silver nanoparticles were fabricated for ultrasensitive detection of antibiotics. The utilization of nanotips-equipped ferroelectric templates significantly enhanced the Raman performance, resulting in excellent sensitivity, reproducibility, and uniformity.
SURFACES AND INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Juanjuan Guo, Yang Xu, Caili Fu, Longhua Guo
Summary: Surface-enhanced Raman spectroscopy (SERS) is a promising analytical technique with sensitivity at the single-molecule level, but faces challenges in preparing large-scale, reproducible, and highly sensitive substrates. In this study, a new strategy using CTAB as a connection agent successfully fabricates an efficient Ag collide SERS substrate, demonstrating significant improvement in detection efficiency and reproducibility for applications on a large scale.
Article
Electrochemistry
Sheila Hernandez, William Cheuquepan, Martin Perez-Estebanez, Aranzazu Heras, Alvaro Colina
Summary: Raman spectroscopy is a powerful analysis technique that is greatly enhanced with the use of Surface-Enhanced Raman scattering (SERS) and Electrochemical-Surface Oxidation Enhanced Raman Scattering (EC-SOERS). The electrogeneration of silver hexacyanoferrate (II) nanocrystals has been developed as a new EC-SOERS substrate, which offers a highly sensitive Raman response. This new material can be easily monitored using spectroelectrochemistry, allowing for the detection of target molecules at nanomolar levels.
ELECTROCHIMICA ACTA
(2023)
Review
Chemistry, Analytical
Mohamed O. Amin, Entesar Al-Hetlani, Igor K. Lednev
Summary: Fingermark analysis is a key tool in criminal investigation, and the biochemical composition of FMs has attracted considerable attention as a vital source of forensic evidence. Vibrational spectroscopy is used to better understand the chemistry of latent FMs and improve detection methods. The article critically reviews the advances in FM analysis using vibrational spectroscopic techniques over the past 10 years, highlighting current limitations and discussing ways to overcome them to support the development of FM analysis techniques meeting modern forensic science requirements.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Xinlei Chen, Shiyi Chen, Xuele Lin, Jingxuan Zhou, Xingjun Gao, Yaoqi Zhen, Xiaodan Ma, Shouwen Jin, Linfang Shi, Hui Liu, Daqi Wang
Summary: Nine mixed-ligand Cd2+ complexes with different geometric structures were synthesized and characterized. The complexes exhibit various coordination modes and form both intra- and intermolecular hydrogen bonds.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Rupali Mahajan, Abhishek Sharma, Bhagyashree Patra, Lijo Mani, Parul Grover, Sandeep Kumar, Santosh Kumar Guru, Gananadhamu Samanthula, Amol G. Dikundwar, Amit Asthana
Summary: This research article provides a comprehensive characterization and toxicological assessment of a photoisomeric impurity of the antianemic drug Roxadustat. The impurity has a distinct structure compared to the drug and its formation due to light exposure is a concern. Through various experiments, including single crystal XRD, physicochemical characterization, and in vitro cytotoxicity assays, the researchers confirmed the structure of the impurity, evaluated its conversion with Roxadustat, and assessed its toxicological activity. These findings contribute to the understanding of drug stability, safety, and formulation development.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Laila S. Alqarni, Azzah M. Alghamdi, Nuha Y. Elamin, A. Rajeh
Summary: The solution casting method was used to produce a new type of nanocomposites made of chitosan, gelatin, and co-doped ZnO nanoparticles. The addition of 3.5% co-doped ZnO nanoparticles improved the physicochemical characteristics and antimicrobial effects of the nanocomposites, indicating their significant potential in food packaging and energy storage.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ruchi Gaur
Summary: The structure and intermolecular interactions of a newly synthesized bis-chalcone THXA were studied using experimental and computational methods. The importance of non-covalent interactions such as pi center dot center dot center dot pi, C-H center dot center dot center dot S, and C-H center dot center dot center dot pi was revealed.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Andrii Bazylevich, Leonid Patsenker, Sarit Aviel-Ronen, Gary Gellerman
Summary: Drug combination therapy is commonly used for treating various skin disorders, but its effectiveness is often limited. In this study, researchers synthesized conjugates of anti-pigmenting drugs and hyaluronic acid (HA) to improve treatment efficacy. These HA-drug conjugates exhibited measurable drug release profiles and demonstrated superior depigmentation effects compared to control groups in a swine model.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Xiaodan Ma, Xinlei Chen, Yaoqi Zhen, Xunjie Zheng, Chengzhe Shi, Shouwen Jin, Bin Liu, Bin Chen, Daqi Wang
Summary: Cocrystallization experiments between minoxidil and aryl acids coformers resulted in the successful formation of multi-component samples. The nature of these samples was determined using various techniques and their structural and supramolecular aspects were investigated. The outcomes revealed the importance of nonbonding contacts and different types of interactions in stabilizing and expanding the crystal structures.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Najla A. Alshaye, Magdy A. Ibrahim, Al-Shimaa Badran
Summary: The chemical behavior of 3-substituted-6,8-dimethylchromones towards phenylhydrazine was examined. Different reaction conditions produced various products, and the molecular geometries and reactivity descriptors of the compounds were also investigated. The results suggest that these compounds are suitable for nonlinear optical applications.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Hayette Alliouche, Houria Bouria, Rafik Bensegueni, Mounia Guergouri, Abdelmalek Bouraiou, Ali Belfaitah
Summary: In this paper, a combined experimental and theoretical study was conducted to synthesize and characterize new 2-quinolone-piperidine and -morpholine hybrids. The results from experiments were validated using computational calculations, and the affinity between these compounds and Acetylcholinesterase/Butyrylcholinesterase was estimated through molecular docking.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-Lai Liu, Jian-Ling Ni, Li-Zhuang Chen, Qiang Gao, Fang-Ming Wang
Summary: This study synthesized and characterized a novel Mn-based LMOF, and achieved good results in detecting heavy metal Al3+ in water, showing good stability, high selectivity and sensitivity. This provides new insights into the potential applications of Mn-based MOFs in chemical sensing.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Jun-Xia Li, Yi-Jing Lu, Ke-Ying Quan, Li-Bing Wu, Xun Feng, Wei-Zhou Wang
Summary: This study synthesized two cobalt(II) complexes and analyzed their crystal structures using single-crystal X-ray diffraction. The results showed that the crystal structures of these complexes were different, and they exhibited different crystal packing and magnetic properties.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Yang Li, Yan Zhang, Hong Xu, Min Li, Zhen Li, Zi-yu Song, Ji-shi Chen, Yan-Jun Liu, Yong Sun, Zhao Yang
Summary: This study reports the synthesis and solid-state characterization of a new pharmaceutical cocrystal, PRO-BPE, which can enhance the solubility of the highly water-insoluble prodrug probenecid. The PRO-BPE cocrystals were found to have superior water solubility compared to pure PRO. This research provides valuable insights into improving the solubility of poorly soluble drugs.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Lucas G. B. Felicio, Bianca B. M. Vieira, Ivana S. Lula, Renata Diniz, Frank Alexis, Flavio B. Miguz, Frederico B. De Sousa
Summary: A novel spiropyran derivative was synthesized for heavy metals sensing in water. The results demonstrated that the new derivative can serve as a rapid, sensitive, and simple tool for detecting Hg2+ ions in water with high selectivity.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Junqing Meng, Jie Wang, Lijuan Wang, Chunhui Lyu, Haiyan Chen, Yingpei Lyu, Baisheng Nie
Summary: Material modification with low surface energy can achieve lower surface free energy on micro-and nano-rough structures, which is crucial for developing superhydrophobic surfaces. In this study, attapulgite (APT) was modified with alkylamine, alkylammonium salt, and stearic acid, and the interaction between low surface materials and attapulgite was explained. The results showed that the hydrophobicity of APT was significantly modified by the modifiers, and the surface free energy of the composites first decreased and then increased with increasing molecular number of low surface energy monomers.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Karan Goswami, Dipak Das, Parthasarathi Bera, Sounak Roy, Md. Motin Seikh, Prasanta Kumar Sinha, Arup Gayen
Summary: This work presents the development of a simple and highly active heterogeneous Pd catalyst for Suzuki-Miyaura carbon-carbon cross-coupling reaction. The NiPdFe-1 catalyst shows the best activity and stability among the prepared catalysts. It efficiently promotes the coupling reaction between aryl bromide and phenyl boronic acid under mild reaction conditions with high isolated yields.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ekta Pardhi, Devendra Singh Tomar, Rahul Khemchandani, Gananadhamu Samanthula, Pankaj Kumar Singh, Neelesh Kumar Mehra
Summary: The main aim of this study was to prepare a drug-drug coamorphous system to improve the physiochemical properties, solubility and stability of Apremilast and Indomethacin. Various solid-state characterization techniques were used to characterize the prepared system. Molecular level interactions were studied using molecular modeling and ATR-FTIR and 1H NMR. Solubility and dissolution studies showed the benefits of the coamorphous system. The system was found to be stable for a period of five months. Permeation study also demonstrated improved flux for both drugs compared to their crystalline forms. The coamorphous system showed anti-psoriatic and anti-melanogenic activity based on molecular docking results. Overall, the developed CAM-based supersaturated system exhibited improved physicochemical properties and physical stability.
JOURNAL OF MOLECULAR STRUCTURE
(2024)