Analysis of full and partial agonists binding to β2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

Identifying conformational changes of the β2 adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators

(2009) Kimberly A. Reynolds et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Selective Structure-Based Virtual Screening for Full and Partial Agonists of the β2 Adrenergic Receptor

(2008) Chris de Graaf et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

(2008) Michael A. Hanson et al.   STRUCTURE

New G-protein-coupled receptor crystal structures: insights and limitations

(2008) B KOBILKA et al.   TRENDS IN PHARMACOLOGICAL SCIENCES