HIF-1α/Beclin1-Mediated Autophagy Is Involved in Neuroprotection Induced by Hypoxic Preconditioning

A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3

(2018) Ruoqiu Fu et al.   Cell Death & Disease

Hypoxia Inducible Factor 1α Plays a Key Role in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Rats

(2018) Jian Yang et al.   Journal of the American Heart Association

Autophagy induction plays a protective role against hypoxic stress in human dental pulp cells

(2017) Sam-Young Park et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Enhanced Autophagy Contributes to Protective Effects of GM1 Ganglioside Against Aβ1-42-Induced Neurotoxicity and Cognitive Deficits

(2017) Ruwei Dai et al.   NEUROCHEMICAL RESEARCH

NAMPT inhibitor protects ischemic neuronal injury in rat brain via anti-neuroinflammation

(2017) Chen-Xiang Chen et al.   NEUROSCIENCE

Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats

(2017) Lixuan Zhan et al.   Cell Death & Disease

Effects of Cobalt Chloride, a Hypoxia-Mimetic Agent, on Autophagy and Atrophy in Skeletal C2C12 Myotubes

(2017) Rui Chen et al.   Biomed Research International

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury

(2016) Cuicui Xie et al.   Autophagy

Circular RNA expression alterations are involved in OGD/R-induced neuron injury

(2016) Shao-Peng Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Knockout of programmed cell death 5 (PDCD5) gene attenuates neuron injury after middle cerebral artery occlusion in mice

(2016) Jianfei Lu et al.   BRAIN RESEARCH

Regulation of autophagy by Beclin 1 in the heart

(2016) Yasuhiro Maejima et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Hypoxia as a therapy for mitochondrial disease

(2016) I. H. Jain et al.   SCIENCE

Potential protective effects of autophagy activated in MPP+ treated astrocytes

(2016) Cunzhou Shen et al.   Experimental and Therapeutic Medicine

Autophagy Inhibitor 3-MA Weakens Neuroprotective Effects of Posttraumatic Brain Injury Moderate Hypothermia

(2016) Yichao Jin et al.   World Neurosurgery

Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line

(2016) Mackenzie M. Shipley et al.   Jove-Journal of Visualized Experiments

MLIF Alleviates SH-SY5Y Neuroblastoma Injury Induced by Oxygen-Glucose Deprivation by Targeting Eukaryotic Translation Elongation Factor 1A2

(2016) Qiuzhen Zhu et al.   PLoS One

Yak Response to High-Altitude Hypoxic Stress by Altering mRNA Expression and DNA Methylation of Hypoxia-Inducible Factors

(2015) Xianrong Xiong et al.   ANIMAL BIOTECHNOLOGY

Divergent roles of BECN1 in LC3 lipidation and autophagosomal function

(2015) Ruina He et al.   Autophagy

Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX

(2015) Paul A. Ney   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proteomic analysis of the mouse brain after repetitive exposure to hypoxia

(2015) Can Cui et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Preconditioning by Oxygen-Glucose Deprivation Preserves Cell Proliferation and Reduces Cytotoxicity in Primary Astrocyte Cultures

(2015) Maria Nikiforou et al.   CNS & Neurological Disorders-Drug Targets

Hypoxia-induced autophagy contributes to the invasion of salivary adenoid cystic carcinoma through the HIF-1α/BNIP3 signaling pathway

(2015) HAIWEI WU et al.   Molecular Medicine Reports

Activation of AKT1/GSK-3β/β-Catenin–TRIM11/Survivin Pathway by Novel GSK-3β Inhibitor Promotes Neuron Cell Survival: Study in Differentiated SH-SY5Y Cells in OGD Model

(2015) B. S. Darshit et al.   MOLECULAR NEUROBIOLOGY

Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic–Ischemic Injury in the Neonatal Rat

(2015) Hannah X. Chu et al.   NEUROCHEMICAL RESEARCH

Current insights into the molecular mechanisms of hypoxic pre- and postconditioning using hypobaric hypoxia

(2015) Elena Rybnikova et al.   Frontiers in Neuroscience

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

(2014) Ruo-Yang Shi et al.   CNS Neuroscience & Therapeutics

Interlinking of Hypoxia and Estrogen in Thyroid Cancer Progression

(2014) S. Rajoria et al.   CURRENT MEDICINAL CHEMISTRY

Autophagy as a pro-death pathway

(2014) Donna Denton et al.   IMMUNOLOGY AND CELL BIOLOGY

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

(2014) Rui Sheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure, function, and epigenetic regulation of BNIP3: a pathophysiological relevance

(2014) Nagarjuna Vasagiri et al.   MOLECULAR BIOLOGY REPORTS

Apigenin Mediated Protection of OGD-Evoked Neuron-Like Injury in Differentiated PC12 Cells

(2014) Huizhen Guo et al.   NEUROCHEMICAL RESEARCH

Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia–ischemia

(2014) R. Ann Sheldon et al.   PEDIATRIC RESEARCH

Preconditioning provides neuroprotection in models of CNS disease: Paradigms and clinical significance

(2014) R. Anne Stetler et al.   PROGRESS IN NEUROBIOLOGY

Increased leptin by hypoxic-preconditioning promotes autophagy of mesenchymal stem cells and protects them from apoptosis

(2014) LiHan Wang et al.   Science China-Life Sciences

p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3

(2013) Erika Yan Wang et al.   HYPERTENSION

Paradoxical Role of 3-Methyladenine in Pyocyanin-Induced Toxicity in 1321N1 Astrocytoma and SH-SY5Y Neuroblastoma Cells

(2013) Amelia J. McFarland et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

BNIP3 mediates pre-myelinating oligodendrocyte cell death in hypoxia and ischemia

(2013) Chengren Li et al.   JOURNAL OF NEUROCHEMISTRY

Hypoxic Preconditioning Alleviates Ethanol Neurotoxicity: The Involvement of Autophagy

(2013) Haiping Wang et al.   NEUROTOXICITY RESEARCH

The Role of Heat Shock Protein 70 in the Protective Effect of YC-1 on β-Amyloid-Induced Toxicity in Differentiated PC12 Cells

(2013) Yung-Chieh Tsai et al.   PLoS One

Autophagosome formation—The role of ULK1 and Beclin1–PI3KC3 complexes in setting the stage

(2013) Martina Wirth et al.   SEMINARS IN CANCER BIOLOGY

Preconditioning Strategy in Stem Cell Transplantation Therapy

(2013) Shan Ping Yu et al.   Translational Stroke Research

Autophagy is a protective response to ethanol neurotoxicity

(2012) Gang Chen et al.   Autophagy

Beclin1: A role in membrane dynamics and beyond

(2012) Ellen Wirawan et al.   Autophagy

Autophagy and cardiovascular aging

(2012) Sreejayan Nair et al.   CELL CYCLE

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

HIF-1 versus HIF-2 — Is one more important than the other?

(2012) Agnieszka Loboda et al.   VASCULAR PHARMACOLOGY

Hypoxic preconditioning in an autohypoxic animal model

(2012) Guo Shao et al.   Neuroscience Bulletin

Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis

(2011) Basant A. Abdulrahman et al.   Autophagy

Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1α/BNIP3 signaling pathway

(2011) Yi Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Proteomic analysis of cPKCβII-interacting proteins involved in HPC-induced neuroprotection against cerebral ischemia of mice

(2011) Xiangning Bu et al.   JOURNAL OF NEUROCHEMISTRY

Differential Effects of HIF-1 Inhibition by YC-1 on the Overall Outcome and Blood-Brain Barrier Damage in a Rat Model of Ischemic Stroke

(2011) Jingqi Yan et al.   PLoS One

Role of autophagy in protection afforded by hypoxic preconditioning against MPP+-induced neurotoxicity in SH-SY5Y cells

(2010) Y.W. Tzeng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Improved survival of mesenchymal stromal cell after hypoxia preconditioning: Role of oxidative stress

(2010) Karen M. Peterson et al.   LIFE SCIENCES

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

The autophagy effector Beclin 1: a novel BH3-only protein

(2009) S Sinha et al.   ONCOGENE