Molecular simulation of Tyr105 phosphorylated pyruvate kinase M2 to understand its structure and dynamics

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

(2013) William J. Israelsen et al.   CELL

Buried and Accessible Surface Area Control Intrinsic Protein Flexibility

(2013) Joseph A. Marsh   JOURNAL OF MOLECULAR BIOLOGY

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

PKM2: A gatekeeper between growth and survival

(2011) Isaac Harris et al.   CELL RESEARCH

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Dominant Negative Mutations Affect Oligomerization of Human Pyruvate Kinase M2Isozyme and Promote Cellular Growth and Polyploidy

(2010) Vibhor Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human pyruvate kinase M2: A multifunctional protein

(2010) Vibhor Gupta et al.   PROTEIN SCIENCE

Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia

(2009) E. Hulleman et al.   HAEMATOLOGICA

Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

(2009) T. Hitosugi et al.   Science Signaling

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE