Selectivity and activation of dopamine D3R from molecular dynamics

Studies on the Interactions between β2 Adrenergic Receptor and Gs Protein by Molecular Dynamics Simulations

(2012) Zhiwei Feng et al.   Journal of Chemical Information and Modeling

Saturation with cholesterol increases vertical order and smoothes the surface of the phosphatidylcholine bilayer: A molecular simulation study

(2011) Elżbieta Plesnar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Theoretical study of 3-D molecular similarity and ligand binding modes of orthologous human and rat D2 dopamine receptors

(2011) Marvin A. Soriano-Ursúa et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Computational Simulation of Drug Delivery at Molecular Level

(2011) Youyong Li et al.   CURRENT MEDICINAL CHEMISTRY

G Protein- and Agonist-Bound Serotonin 5-HT2AReceptor Model Activated by Steered Molecular Dynamics Simulations

(2011) Vignir Ísberg et al.   Journal of Chemical Information and Modeling

Predicted Structures and Dynamics for Agonists and Antagonists Bound to Serotonin 5-HT2B and 5-HT2C Receptors

(2011) Soo-Kyung Kim et al.   Journal of Chemical Information and Modeling

Searching the “Biologically Relevant”Conformation of Dopamine: A Computational Approach

(2011) Sebastian A. Andujar et al.   Journal of Chemical Information and Modeling

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

(2011) Guillaume Lebon et al.   NATURE

The structural basis of agonist-induced activation in constitutively active rhodopsin

(2011) Jörg Standfuss et al.   NATURE

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Structure of an Agonist-Bound Human A2A Adenosine Receptor

(2011) F. Xu et al.   SCIENCE

Recent advances in the search for D3- and D4-selective drugs: probes, models and candidates

(2011) Stefan Löber et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Current perspectives on the selective regulation of dopamine D2 and D3 receptors

(2010) Dong Im Cho et al.   ARCHIVES OF PHARMACAL RESEARCH

Prediction of the Three-Dimensional Structure for the Rat Urotensin II Receptor, and Comparison of the Antagonist Binding Sites and Binding Selectivity between Human and Rat Receptors from Atomistic Simulations

(2010) Soo-Kyung Kim et al.   ChemMedChem

Computational Modeling of Structure-Function of G Protein-Coupled Receptors with Applications for Drug Design

(2010) Y. Li et al.   CURRENT MEDICINAL CHEMISTRY

Computational Modeling Toward Understanding Agonist Binding on Dopamine 3

(2010) Yaxue Zhao et al.   Journal of Chemical Information and Modeling

Structure−Activity Relationships for a Novel Series of Citalopram (1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) Analogues at Monoamine Transporters

(2010) Peng Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Predicted 3D structures for adenosine receptors bound to ligands: Comparison to the crystal structure

(2010) William A. Goddard et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Tetrahydroisoquinoline Derivative SB269,652 Is an Allosteric Antagonist at Dopamine D3 and D2 Receptors

(2010) E. Silvano et al.   MOLECULAR PHARMACOLOGY

The interrelationship of dopamine D2-like receptor availability in striatal and extrastriatal brain regions in healthy humans: A principal component analysis of [18F]fallypride binding

(2010) David H. Zald et al.   NEUROIMAGE

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

(2009) Raquel Ortega et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

977 SB-277011, A SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONIST, DELAYS EJACULATION IN CONSCIOUS AND ANESTHETIZED RATS

(2009) P. Clément et al.   EUROPEAN UROLOGY SUPPLEMENTS

The selective dopamine D3 receptor antagonist SB 277011-A, but not the partial agonist BP 897, blocks cue-induced reinstatement of nicotine-seeking

(2009) Maram A. T. M. Khaled et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

N-(4-(4-(2,3-Dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with Functionalized Linking Chains as High Affinity and Enantioselective D3 Receptor Antagonists∥⊥

(2009) Amy Hauck Newman et al.   JOURNAL OF MEDICINAL CHEMISTRY

The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity

(2008) Panayotis K. Thanos et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR