Article
Biochemistry & Molecular Biology
Dieter Blottner, Daniele Capitanio, Gabor Trautmann, Sandra Furlan, Guido Gambara, Manuela Moriggi, Katharina Block, Pietro Barbacini, Enrica Torretta, Guillaume Py, Angele Chopard, Imre Vida, Pompeo Volpe, Cecilia Gelfi, Michele Salanova
Summary: This study evaluated the efficacy of an antioxidant cocktail in preventing oxidative stress and promoting muscle development during bedrest-induced muscle atrophy. The treatment group showed prevention of redox homeostasis dysregulation, enhanced structural remodeling and myogenesis, and normalization of metabolic pathways, while exhibiting increased antioxidant defense response.
Article
Chemistry, Multidisciplinary
Polyxeni Spiliopoulou, Spyridon Methenitis, Nikolaos Zaras, Angeliki-Nikoletta Stasinaki, Maria Krekoukia, Stavroula Tsitkanou, Gerasimos Terzis
Summary: The aim of this study was to determine the best surrogate of quadriceps hypertrophy by evaluating the four muscle heads of the quadriceps femoris using ultrasonography. The results suggest that changes in muscle hypertrophy in the vastus lateralis and vastus intermedius can significantly predict overall quadriceps hypertrophy in response to resistance training.
APPLIED SCIENCES-BASEL
(2022)
Article
Neurosciences
Miles F. Bartlett, Liam F. Fitzgerald, Jane A. Kent
Summary: The study found that high-intensity exercise leads to increased oxygen consumption, potentially due to mechanisms affecting mitochondrial function or capacity.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Orthopedics
Conglei Dong, Ming Li, Kuo Hao, Chao Zhao, Kang Piao, Wei Lin, Chongyi Fan, Yingzhen Niu, Wang Fei
Summary: In patients with patellofemoral pain syndrome, atrophy of the vastus medialis obliquus and vastus lateralis muscles was found in sections 0-20 mm above the upper pole of the patella, with the atrophy of the vastus medialis obliquus being more pronounced than that of the vastus lateralis muscle.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Orthopedics
Marion Crouzier, Francois Hug, Frances T. Sheehan, Natalie J. Collins, Kay Crossley, Kylie Tucker
Summary: This study aimed to determine whether there is a difference in the torque distribution between the vastus medialis and vastus lateralis in adolescents with and without patellofemoral pain. The results showed that there was no decreased contribution of the vastus medialis to knee extension torque in adolescents with patellofemoral pain compared to controls.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Rehabilitation
Mario Parstorfer, Francesca Profit, Nadine Weiberg, Michaela Wehrstein, Alexander Barie, Birgit Friedmann-Bette
Summary: This study investigated satellite cell content and function of the vastus lateralis muscle after anterior ligament reconstruction. The findings showed that satellite cell apoptosis increased while the total satellite cell number decreased post-reconstruction, suggesting a potential explanation for prolonged quadriceps muscle atrophy.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Multidisciplinary Sciences
Paul Ritsche, Philipp Wirth, Martino Franchi, Oliver Faude
Summary: This study presents a novel semi-automatic ImageJ script (ACSAuto) for quantifying lower limb muscle ACSA, which shows good reliability compared to manual analysis. The script demonstrates high consistency and small mean bias when compared to manual measurements, potentially reducing time needed for evaluating ultrasound images.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Amelie Werkhausen, Oyvind Gloersen, Antoine Nordez, Goran Paulsen, Jens Bojsen-Moller, Olivier R. Seynnes
Summary: In this study, the relationship between rate of force development (RFD) and muscle architecture and dynamics was investigated. It was found that RFD was positively correlated to fascicle shortening velocity, but not to optimal fascicle length or architectural gear ratio. The results highlight the importance of fascicle shortening velocity and force-length-velocity properties for rapid force production, and suggest a possible role of fascicle rotation.
SCIENTIFIC REPORTS
(2022)
Article
Anatomy & Morphology
Kathryn Merle van Boom, Dorothy Breed, Alix Hughes, Dee Blackhurst, Tertius Abraham Kohn
Summary: This study analyzed the skeletal muscle physiology and metabolism of a female Temminck's ground pangolin and found that it primarily relies on oxidative derived energy from fats and carbohydrates, indicating a high endurance capability compared to other wild animals and human endurance athletes. This research provides valuable insights for understanding and conserving this endangered species.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2022)
Article
Rehabilitation
Theresa Maria Betz, Michaela Wehrstein, Fabian Preisner, Martin Bendszus, Birgit Friedmann-bette
Summary: The study found that by standardizing an examination protocol, ultrasound measurements of muscle thickness and subcutaneous adipose tissue thickness showed good reliability and validity, while the cross-sectional area had only average agreement but still showed a strong positive correlation with magnetic resonance imaging measurements.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Geriatrics & Gerontology
Eleanor J. Jones, Jessica Piasecki, Alex Ireland, Daniel W. Stashuk, Philip J. Atherton, Bethan E. Phillips, Jamie S. McPhee, Mathew Piasecki
Summary: Motor unit (MU) expansion plays a crucial role in rescuing denervated muscle fibers to mitigate age-related muscle atrophy, with master athletes demonstrating greater success in this process. Data from intramuscular electromyography studies suggest that MUs located superficially are larger than those located deeper within young muscle. However, the effects of aging and exercise on MU heterogeneity across deep and superficial aspects of vastus lateralis (VL) remain uncertain. The study indicates that MU characteristics may vary with muscle depth within the VL, influenced by both the aging process and exercise levels. Older athletes exhibit a more uniform distribution of MUP size and complexity across muscle depths, potentially due to a higher degree of age-related MU adaptations.
Article
Neurosciences
Jeremie Bouvier, Augustin C. Ogier, Cyril Martin, Alexandre Foure
Summary: This study investigated the effect of knee joint angle on the mechanical properties of the vastus medialis (VM) and vastus lateralis (VL) during voluntary contractions. The results showed that the Young's modulus of the VM did not differ significantly among torque levels and knee angles, while the Young's modulus of the VL was significantly higher at 25% muscle contraction for a knee angle of 100 degrees compared to 75% muscle contraction for the same knee angle, and it was also higher at 25% muscle contraction for a knee angle of 100 degrees compared to 50 degrees.
JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY
(2023)
Article
Sport Sciences
Rebekah S. Carpenter, Michael A. Samaan, Jody L. Clasey, Tim A. Butterfield, Fan Gao, Peter A. Hardy, Lance M. Bollinger
Summary: This study investigated the relationship between diffusion tensor imaging (DTI) parameters of the vastus lateralis (VL) and in vivo knee extensor contractile function. The results showed that mean diffusivity (MD) and radial diffusivity (RD) were moderately correlated with peak twitch force and rate of force development, while fractional anisotropy (FA) and axial diffusivity (AD) were moderately inversely related to percent change in maximal voluntary isometric contraction (MVIC) following exercise.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Geriatrics & Gerontology
Isobel Jacob, Mark Johnson, Gareth Jones, Ashley Jones, Peter Francis
Summary: This study aimed to evaluate age-related differences in muscle morphology, function, and functional capability in healthy adults. The results showed negative correlations between age and muscle thickness, pennation angle, fascicle length, maximal displacement, grip strength, and the 1-min chair rise test, while positive correlations were observed between age and the echo intensity of the muscle and total contraction time. The differences in muscle health were noticeable at 50 years of age, and females had larger differences compared to males. Physical activity was suggested to mitigate the detrimental changes.
Article
Nutrition & Dietetics
Mary F. O'Leary, Sarah R. Jackman, Vlad R. Sabou, Matthew I. Campbell, Jonathan C. Y. Tang, John Dutton, Joanna L. Bowtell
Summary: Shatavari may improve muscle function and contractility via myosin conformational change, warranting further investigation in larger and more diverse cohorts.