MOLECULAR EVOLUTION OF GPCRS: GLP1/GLP1 receptors

Expansion of Secretin-Like G Protein-Coupled Receptors and Their Peptide Ligands via Local Duplications Before and After Two Rounds of Whole-Genome Duplication

(2013) Jong-Ik Hwang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structure of the human glucagon class B G-protein-coupled receptor

(2013) Fai Yiu Siu et al.   NATURE

A Novel Glucagon-Related Peptide (GCRP) and Its Receptor GCRPR Account for Coevolution of Their Family Members in Vertebrates

(2013) Cho Rong Park et al.   PLoS One

Molecular evolution of peptidergic signaling systems in bilaterians

(2013) O. Mirabeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a Novel Glucagon-like Peptide (GCGL) and Its Receptor (GCGLR) in Chickens: Evidence for the Existence ofGCGLandGCGLRGenes in Nonmammalian Vertebrates

(2012) Yajun Wang et al.   ENDOCRINOLOGY

Using Paleogenomics to Study the Evolution of Gene Families: Origin and Duplication History of the Relaxin Family Hormones and Their Receptors

(2012) Sergey Yegorov et al.   PLoS One

Agnathan VIP, PACAP and Their Receptors: Ancestral Origins of Today's Highly Diversified Forms

(2012) Stephanie Y. L. Ng et al.   PLoS One

Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor

(2012) A. Kirkpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for negative regulation of the glucagon receptor

(2012) C. M. Koth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incretin hormones and the expanding families of glucagon-like sequences and their receptors

(2011) D. M. Irwin et al.   DIABETES OBESITY & METABOLISM

Evolutionarily Conserved Residues at Glucagon-like Peptide-1 (GLP-1) Receptor Core Confer Ligand-induced Receptor Activation

(2011) Mi Jin Moon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation

(2011) Cassandra Koole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor

(2011) K. Coopman et al.   MOLECULAR ENDOCRINOLOGY

Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1

(2011) Mi Jin Moon et al.   MOLECULES AND CELLS

The serendipitous origin of chordate secretin peptide family members

(2010) João CR Cardoso et al.   BMC EVOLUTIONARY BIOLOGY

Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius

(2010) Kazunari Hisadome et al.   DIABETES

Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain

(2010) Kalyana C. Venneti et al.   FEBS LETTERS

Revisiting the evolution of gonadotropin-releasing hormones and their receptors in vertebrates: Secrets hidden in genomes

(2010) Dong-Kyu Kim et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Spatial Approximations between Residues 6 and 12 in the Amino-terminal Region of Glucagon-like Peptide 1 and Its Receptor

(2010) Quan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand

(2010) T. Yaqub et al.   MOLECULAR PHARMACOLOGY

Tyr1 and Ile7 of glucose-dependent insulinotropic polypeptide (GIP) confer differential ligand selectivity toward GIP and glucagon-like peptide-1 receptors

(2010) Mi Jin Moon et al.   MOLECULES AND CELLS

Characterization of the receptors for chicken GHRH and GHRH-related peptides: Identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP)

(2009) Y. Wang et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Molecular Evolution of Multiple Forms of Kisspeptins and GPR54 Receptors in Vertebrates

(2009) Yeo Reum Lee et al.   ENDOCRINOLOGY

Molecular Basis of Glucagon-like Peptide 1 Docking to Its Intact Receptor Studied with Carboxyl-terminal Photolabile Probes

(2009) Quan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

(2009) Christina Rye Underwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

(2008) Karl JV Nordström et al.   BMC EVOLUTIONARY BIOLOGY

Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain

(2008) Steffen Runge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists

(2008) Fu Lin et al.   JOURNAL OF MOLECULAR MODELING

The amphioxus genome and the evolution of the chordate karyotype

(2008) Nicholas H. Putnam et al.   NATURE

Class-B GPCR activation: is ligand helix-capping the key?

(2008) Jean-Michel Neumann et al.   TRENDS IN BIOCHEMICAL SCIENCES