Puerarin protects pancreatic  -cell survival via PI3K/Akt signaling pathway

Marked Expansion of Exocrine and Endocrine Pancreas With Incretin Therapy in Humans With Increased Exocrine Pancreas Dysplasia and the Potential for Glucagon-Producing Neuroendocrine Tumors

(2013) A. E. Butler et al.   DIABETES

Anti-diabetic effects of puerarin, isolated from Pueraria lobata (Willd.), on streptozotocin-diabetogenic mice through promoting insulin expression and ameliorating metabolic function

(2013) Ka Wu et al.   FOOD AND CHEMICAL TOXICOLOGY

Prevalence and Control of Diabetes in Chinese Adults

(2013) Yu Xu   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Puerarin stimulates proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells via ER-dependent MEK/ERK and PI3K/Akt activation

(2013) Yue Wang et al.   PHYTOMEDICINE

Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots

(2012) Seong Eun Jin et al.   ARCHIVES OF PHARMACAL RESEARCH

Puerarin attenuates endothelial insulin resistance through inhibition of inflammatory response in an IKKβ/IRS-1-dependent manner

(2012) Fang Huang et al.   BIOCHIMIE

Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes

(2012) S. Liu et al.   DIABETOLOGIA

Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death

(2012) Guoqi Zhu et al.   NEUROCHEMISTRY INTERNATIONAL

The Chinese Pueraria root extract (Pueraria lobata) ameliorates impaired glucose and lipid metabolism in obese mice

(2012) Jeevan K. Prasain et al.   PHYTOMEDICINE

Puerarin Accelerates Peripheral Nerve Regeneration

(2011) Shih-Wei Hsiang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Neuroprotective effects of puerarin against beta-amyloid-induced neurotoxicity in PC12 cells via a PI3K-dependent signaling pathway

(2011) Guihua Xing et al.   BRAIN RESEARCH BULLETIN

Puerarin protects differentiated PC12 cells from H2O2-induced apoptosis through the PI3K/Akt signalling pathway

(2011) Qin Zhang et al.   CELL BIOLOGY INTERNATIONAL

Therapy in the Early Stage: Incretins

(2011) S. Cernea et al.   DIABETES CARE

Puerarin protects human umbilical vein endothelial cells against high glucose-induced apoptosis by upregulating heme oxygenase-1 and inhibiting calpain activation

(2011) Ying-Ying Chen et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Puerarin activates endothelial nitric oxide synthase through estrogen receptor-dependent PI3-kinase and calcium-dependent AMP-activated protein kinase

(2011) Yong Pil Hwang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Puerarin protects rat kidney from lead-induced apoptosis by modulating the PI3K/Akt/eNOS pathway

(2011) Chan-Min Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Puerarin enhances adipocyte differentiation, adiponectin expression, and antioxidant response in 3T3-L1 cells

(2010) Ok-Hwan Lee et al.   BIOFACTORS

Islet Transplantation a Decade Later and Strategies for Filling a Half-Full Glass

(2010) R. P. Robertson   DIABETES

Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet

(2010) Wei Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Extranuclear estrogen receptor-  stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

(2010) W. P. S. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importance of Extranuclear Estrogen Receptor-  and Membrane G Protein-Coupled Estrogen Receptor in Pancreatic Islet Survival

(2009) S. Liu et al.   DIABETES

In vivo antioxidative activity of a quantified Pueraria lobata root extract

(2009) Lidiya Bebrevska et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of puerarin on receptor for advanced glycation end products in nephridial tissue of streptozotocin-induced diabetic rats

(2009) Jian Guo Shen et al.   MOLECULAR BIOLOGY REPORTS

Protective effect of puerarin on diabetic retinopathy in rats

(2008) Yan Teng et al.   MOLECULAR BIOLOGY REPORTS

Mechanism of phytoestrogen puerarin-mediated cytoprotection following oxidative injury: Estrogen receptor-dependent up-regulation of PI3K/Akt and HO-1

(2008) Yong Pil Hwang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY