Estrogens and atherosclerosis: insights from animal models and cell systems

Chronic Estradiol Administration In Vivo Promotes the Proinflammatory Response of Macrophages to TLR4 Activation: Involvement of the Phosphatidylinositol 3-Kinase Pathway

(2014) B. Calippe et al.   JOURNAL OF IMMUNOLOGY

Estrogen Receptor  , but Not  , Is Required for Optimal Dendritic Cell Differentiation and CD40-Induced Cytokine Production

(2014) V. Douin-Echinard et al.   JOURNAL OF IMMUNOLOGY

Estradiol Acts Directly on Bone Marrow Myeloid Progenitors to Differentially Regulate GM-CSF or Flt3 Ligand-Mediated Dendritic Cell Differentiation

(2014) E. Carreras et al.   JOURNAL OF IMMUNOLOGY

17 -Estradiol Alters the Activity of Conventional and IFN-Producing Killer Dendritic Cells

(2014) M. C. Siracusa et al.   JOURNAL OF IMMUNOLOGY

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase

(2011) Derya Sivritas et al.   BASIC RESEARCH IN CARDIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Attenuation of Atherogenesis via the Anti-inflammatory Effects of the Selective Estrogen Receptor Beta Modulator 8β-VE2

(2011) Jiangfeng Sun et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Estrogen-responsive nitroso-proteome in uterine artery endothelial cells: Role of endothelial nitric oxide synthase and estrogen receptor-β

(2011) Hong-hai Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The effect of 17β-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu

(2011) Michael P Corcoran et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Cellular and molecular actions displayed by estrone on vascular endothelium

(2011) M. Belén Rauschemberger et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Activation function 2 (AF2) of estrogen receptor-α is required for the atheroprotective action of estradiol but not to accelerate endothelial healing

(2011) Audrey Billon-Galés et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid-specific estrogen receptor   deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

(2011) V. Ribas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

27-Hydroxycholesterol: the first identified endogenous SERM

(2011) Michihisa Umetani et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries

(2010) Brad R. S. Broughton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Estrogen Receptors and Endothelium

(2010) Jean-François Arnal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The androgen derivative 5α-androstane-3β,17β-diol inhibits tumor necrosis factor α and lipopolysaccharide induced inflammatory response in human endothelial cells and in mice aorta

(2010) Giuseppe Danilo Norata et al.   ATHEROSCLEROSIS

Proatherogenic effects of estradiol in a model of accelerated atherosclerosis in ovariectomized ApoE-deficient mice

(2010) Till Freudenberger et al.   BASIC RESEARCH IN CARDIOLOGY

Estradiol-17β Stimulates Specific Receptor and Endogenous Nitric Oxide-Dependent Dynamic Endothelial ProteinS-Nitrosylation: Analysis of EndothelialNitrosyl-Proteome

(2010) Hong-hai Zhang et al.   ENDOCRINOLOGY

Androgen Receptor-Dependent and Independent Atheroprotection by Testosterone in Male Mice

(2010) Johan Bourghardt et al.   ENDOCRINOLOGY

Minireview: Rapid Actions of Sex Steroids in the Endothelium

(2010) Renee W. Y. Chow et al.   ENDOCRINOLOGY

Selective estrogen receptor-α agonist provides widespread heart and vascular protection with enhanced endothelial progenitor cell mobilization in the absence of uterotrophic action

(2010) Chiara Bolego et al.   FASEB JOURNAL

17 -Estradiol Promotes TLR4-Triggered Proinflammatory Mediator Production through Direct Estrogen Receptor   Signaling in Macrophages In Vivo

(2010) B. Calippe et al.   JOURNAL OF IMMUNOLOGY

Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages

(2010) A. J. Murphy et al.   JOURNAL OF IMMUNOLOGY

17β-estradiol down-regulates lipopolysaccharide-induced MCP-1 production and cell migration in vascular smooth muscle cells

(2010) Ping Jiang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Estradiol selectively stimulates endothelial prostacyclin production through estrogen receptor-α

(2010) Agua Sobrino et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Age and 17β-estradiol effects on blood–brain barrier tight junction and estrogen receptor proteins in ovariectomized rats

(2010) Karin E. Sandoval et al.   MICROVASCULAR RESEARCH

GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages

(2010) Jennifer A. Rettew et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estradiol induces endothelial cell migration and proliferation through estrogen receptor-enhanced RhoA/ROCK pathway

(2010) Pilar J. Oviedo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Acute effects of 2-methoxyestradiol on endothelial aortic No release in male and ovariectomized female rats

(2010) Francisco J. Fenoy et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of 17 β-estradiol on lipopolysacharride-induced intracellular adhesion molecule-1 mRNA expression and Ca2+ homeostasis alteration in human endothelial cells

(2010) Der Thor et al.   VASCULAR PHARMACOLOGY

Estrogen receptor-beta mediates cyclooxygenase-2 expression and vascular prostanoid levels in human placental villous endothelial cells

(2009) Emily J. Su et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30

(2009) Qingming Ding et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Heat Shock Protein 27 Protects Against Atherogenesis via an Estrogen-Dependent Mechanism

(2009) Katey Rayner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Claudin-5 as a Novel Estrogen Target in Vascular Endothelium

(2009) Malgorzata Burek et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4

(2009) E. Carreras et al.   BLOOD

Endothelial Estrogen Receptor-α Plays a Crucial Role in the Atheroprotective Action of 17β-Estradiol in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Audrey Billon-Galés et al.   CIRCULATION

Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity

(2009) Elvira Haas et al.   CIRCULATION RESEARCH

Estrogens Augment Cell Surface TLR4 Expression on Murine Macrophages and Regulate Sepsis Susceptibilityin Vivo

(2009) Jennifer A. Rettew et al.   ENDOCRINOLOGY

Effects of Oral Estrogen on Aortic ROS-Generating and -Scavenging Enzymes and Atherosclerosis in apoE-Deficient Mice

(2009) Lih-Yuh Chen Wing et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cardiovascular risk in menopausal women and prevalent related co-morbid conditions: facing the post-Women's Health Initiative era

(2009) Faustino R. Pérez-López et al.   FERTILITY AND STERILITY

Oestrogen modulates human macrophage apoptosisviadifferential signalling through oestrogen receptor-α and β

(2009) Manikandan Subramanian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The unfolding stories of GPR30, a new membrane-bound estrogen receptor

(2009) Marcello Maggiolini et al.   JOURNAL OF ENDOCRINOLOGY

PPAR-  Contributes to the Anti-Inflammatory Activity of 17 -Estradiol

(2009) C. Crisafulli et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Human macrophage cholesterol efflux potential is enhanced by HDL-associated 17β-estradiol fatty acyl esters

(2009) Robert M. Badeau et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Complex Regulation and Function of the Inflammatory Smooth Muscle Cell Phenotype in Atherosclerosis

(2009) Anthony Wayne Orr et al.   JOURNAL OF VASCULAR RESEARCH

ERB-041, a selective ERβ agonist, inhibits iNOS production in LPS-activated peritoneal macrophages of endometriosis via suppression of NF-κB activation

(2009) Wang Xiu-li et al.   MOLECULAR IMMUNOLOGY

17β-Estradiol Enhances the Response of Plasmacytoid Dendritic Cell to CpG

(2009) Xiaoxi Li et al.   PLoS One

Estradiol Stimulates Vasodilatory and Metabolic Pathways in Cultured Human Endothelial Cells

(2009) Agua Sobrino et al.   PLoS One

The transactivating function 1 of estrogen receptor α is dispensable for the vasculoprotective actions of 17β-estradiol

(2009) Audrey Billon-Galés et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential vascular actions of 2-methoxyestradiol

(2009) Raghvendra K. Dubey et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A selective estrogen receptor modulator inhibits TNF-α-induced apoptosis by activating ERK1/2 signaling pathway in vascular endothelial cells

(2009) Jing Yu et al.   VASCULAR PHARMACOLOGY

17β-Estradiol Prevents Early-Stage Atherosclerosis in Estrogen Receptor-Alpha Deficient Female Mice

(2009) Amparo C. Villablanca et al.   Journal of Cardiovascular Translational Research

Role of Smooth Muscle Cells in the Initiation and Early Progression of Atherosclerosis

(2008) Amanda C. Doran et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Timing of estrogen replacement influences atherosclerosis progression and plaque leukocyte populations in ApoE−/− mice

(2008) Jennifer A. Cann et al.   ATHEROSCLEROSIS

Genistein inhibits the development of atherosclerosis via inhibiting NF-κB and VCAM-1 expression in LDLR knockout mice

(2008) Juejin Wang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Estrogen Receptor-α and Endothelial Nitric Oxide Synthase Nuclear Complex Regulates Transcription of Human Telomerase

(2008) Annalisa Grasselli et al.   CIRCULATION RESEARCH

Extracellular Release of the Atheroprotective Heat Shock Protein 27 Is Mediated by Estrogen and Competitively Inhibits acLDL Binding to Scavenger Receptor-A

(2008) Katey Rayner et al.   CIRCULATION RESEARCH

Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor   in Brain Endothelial Cells

(2008) A. Razmara et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Suppression of NO production and 8-nitroguanosine formation by phenol-containing endocrine-disrupting chemicals in LPS-stimulated macrophages: Involvement of estrogen receptor-dependent or -independent pathways

(2008) Jun Yoshitake et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of estradiol and progesterone on the proinflammatory cytokine production by mononuclear cells from patients with chronic hepatitis C

(2008) Ying Yuan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Estrogen prevents cholesteryl ester accumulation in macrophages induced by the HIV protease inhibitor ritonavir

(2007) Melinda E. Wilson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

17β-Estradiol's salutary effects on splenic dendritic cell functions following trauma–hemorrhage are mediated via estrogen receptor-α

(2007) Takashi Kawasaki et al.   MOLECULAR IMMUNOLOGY