Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance

Title
Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance
Authors
Keywords
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Journal
JOURNAL OF MOLECULAR BIOLOGY
Volume 387, Issue 5, Pages 1298-1308
Publisher
Elsevier BV
Online
2009-02-27
DOI
10.1016/j.jmb.2009.02.045

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