RecurrentStaphylococcus aureusabscess and fatal pneumococcal septicemia due to IRAK-4 deficiency

Impaired T-cell receptor activation in IL-1 receptor–associated kinase-4–deficient patients

(2010) Douglas R. McDonald et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

(2010) Capucine Picard et al.   MEDICINE

Impaired neutrophil migration and phagocytosis in IRAK-4 deficiency

(2009) Gerben Bouma et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Role of Toll-Like Receptor Signaling in Human Immunodeficiencies

(2009) Hanna Suhir et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

IRAK-4 Inhibitors for Inflammation

(2009) Zhulun Wang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Successful prevention of severe infection in Japanese siblings with interleukin-1 receptor–associated kinase 4 deficiency

(2009) Hideto Yoshikawa et al.   JOURNAL OF PEDIATRICS

Signalling mechanisms for Toll-like receptor-activated neutrophil exocytosis: key roles for interleukin-1-receptor-associated kinase-4 and phosphatidylinositol 3-kinase but not Toll/IL-1 receptor (TIR) domain-containing adaptor inducing IFN-β (TRIF)

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