Article
Public, Environmental & Occupational Health
Li Sun, Qianlan Wu, Huiying Wang, Juning Liu, Yan Shao, Rong Xu, Tian Gong, Xiaoju Peng, Baoli Zhang
Summary: This study investigates the association between maternal exposure to air pollutants and the risk of congenital heart defects in Suzhou, China. The results suggest that exposure to PM2.5 and NO2 is associated with an increased risk of CHDs.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Huazhang Miao, Qinghui Zeng, Zengping Shi, Yi Xia, Lushaobo Shi, Dongxue Chen, Pi Guo, Yingxian Zhu, Dong Wang
Summary: This study analyzed a substantial cohort of perinatal fetuses in South China from 2016 to 2020 to characterize the spatial-temporal patterns of congenital heart defects prevalence. The results showed geographical variations in the prevalence of congenital heart defects, with higher rates observed in the Pearl River Delta region and urban areas.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Xuelian Yuan, Fengchao Liang, Jun Zhu, Keyong Huang, Li Dai, Xiaohong Li, Yanping Wang, Qi Li, Xiangfeng Lu, Jianfeng Huang, Lihui Liao, Yang Liu, Dongfeng Gu, Hanmin Liu, Fangchao Liu
Summary: This study investigated the association between maternal exposure to fine particulate matter (PM2.5) and fetal congenital heart defects (CHDs) in China. The results showed that higher maternal PM2.5 exposure, especially during the preconception period, increased the risk of certain types of CHDs in offspring. The findings highlight the importance of improving air quality in China and other highly polluted regions for CHD prevention.
Article
Public, Environmental & Occupational Health
Xiao Jin, Wei Ni, Guolan Wang, Qin Wu, Jun Zhang, Guoju Li, Na Jiao, Wenjing Chen, Qing Liu, Li Gao, Quansheng Xing
Summary: This study conducted in Qingdao, China, found that congenital heart disease (CHD) is a serious health issue with a prevalence similar to existing research. The positive rate of prenatal CHD screening was higher than the incidence of neonatal CHD. Risk factors for CHD were identified in the study, which could have significant implications for developing CHD intervention strategies.
Article
Cardiac & Cardiovascular Systems
Parag N. Jain, Katherine B. Salciccioli, Danielle Guffey, Jinyoung Byun, Timothy B. Cotts, Peter Ermis, Michael Gaies, Nancy Ghanayem, Francis Kim, Javier J. Lasa, Andrew Smith, Stephanie Fuller
Summary: This study analyzed the postoperative care of adults with congenital heart disease in pediatric cardiac intensive care units, finding that high complexity operations, previous sternotomies, preoperative arrhythmias, renal dysfunction, and respiratory failure are independent risk factors for prolonged length of stay and/or major complications.
ANNALS OF THORACIC SURGERY
(2022)
Article
Public, Environmental & Occupational Health
Xingdi Yang, Jianjuan Zeng, Yiping Gu, Yiming Fang, Caiyun Wei, Shengkui Tan, Xiaoying Zhang
Summary: This hospital-based study in Guilin, China, aimed to determine the prevalence of birth defects in the region and classify them based on clinical presentation and causation. Of the 147,817 births recorded, 2,003 infants were diagnosed with BDs, with a total prevalence rate of 13.55 per 1,000 births. The study found that congenital heart defects, polydactyly, syndactyly, malformations of the external ear, and talipes equinovarus were the most common BD types.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Bo-Yi Yang, Yanji Qu, Yuming Guo, Iana Markevych, Joachim Heinrich, Michael S. Bloom, Zhipeng Bai, Luke C. Knibbs, Shanshan Li, Gongbo Chen, Bin Jalaludin, Lidia Morawska, Meng Gao, Bin Han, Yunjiang Yu, Xiao-Xuan Liu, Yanqiu Ou, Jinzhuang Mai, Xiangmin Gao, Yong Wu, Zhiqiang Nie, Xiao-Wen Zeng, Li-Wen Hu, Xubo Shen, Yuanzhong Zhou, Shao Lin, Xiaoqing Liu, Guang-Hui Dong
Summary: The study found that maternal exposure to air pollution during pregnancy, particularly in the first trimester, is associated with an increased risk of CHD in offspring. No significant associations were observed for exposure to air pollutants during the second and third trimesters. The associations between air pollutants and different CHD subtypes varied.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Cardiac & Cardiovascular Systems
Patryk Leczycki, Maciej Banach, Marek Maciejewski, Agata Bielecka-Dabrowa
Summary: In recent decades, there has been a significant increase in the number of adults with congenital heart diseases (ACHD), necessitating thorough evaluation of their current condition. There is currently a lack of universal parameters or scales to easily assess the deterioration of ACHD patients' condition, emphasizing the need to identify widely available, cost-effective, and user-friendly factors. Studies have shown potential prognostic factors including echocardiography and magnetic resonance imaging, cardiopulmonary exercise testing, and biomarkers. However, further research is needed to create a specific assessment panel for patients with specific congenital heart diseases.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Markus Schwerzmann, Francisco Javier Ruperti-Repilado, Helmut Baumgartner, Berto Bouma, Judith Bouchardy, Werner Budts, Laurence Campens, Massimo Chessa, Maria Jesus del Cerro Marin, Harald Gabriel, Pastora Gallego, Rocio Garcia-Orta, Ana Elvira Gonzalez, Annette Schophuus Jensen, Magalie Ladouceur, Berta Miranda-Barrio, Marielle Morissens, Agnes Pasquet, Joaquin Rueda, Annemien E. van den Bosch, Heleen Berdina van der Zwaan, Daniel Tobler, Matthias Greutmann
Summary: This study aimed to collect clinical outcome data and identify risk factors for a complicated course of COVID-19 in patients with adult congenital heart disease (ACHD). Risk factors such as age, obesity, and multiple comorbidities were associated with an increased risk of a complicated COVID-19 course in ACHD patients. Cyanotic heart disease, including unrepaired cyanotic defects or Eisenmenger syndrome, were identified as particularly high-risk congenital cardiac defects in ACHD patients.
Review
Cell Biology
Yuwen Chen, Deyong Xiao, Lu Zhang, Chen-Leng Cai, Bai-Yan Li, Ying Liu
Summary: Tbx20, a member of the T-box gene family, plays crucial roles in cardiovascular development and homeostasis, as well as cardiac remodeling in response to pathophysiological stresses. Mutations and genetic variants in TBX20 are associated with a wide spectrum of congenital heart defects and heart diseases.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Forestry
Mingyu Lan, Chunquan Xue, Jiazhi Yang, Ning Wang, Chuanxi Sun, Guozhang Wu, Hongyu Chen, Zhiyao Su
Summary: This study examined the effects of different rocky desertification degrees on plant diversity and soil fertility in northern Guangdong over long periods of time. The results showed that certain plant species were relatively abundant in the rocky desertification areas, and some species could be used as indicators for rocky desertification. There were significant differences in plant community compositions and soil physicochemical properties between different degrees of rocky desertification. The study also found a significant correlation between soil physicochemical properties and species diversity, with total phosphorus and available phosphorus being the most important factors affecting plant community structures.
Article
Cardiac & Cardiovascular Systems
Theodora Fteropoulli, Manavi Tyagi, Shashivadan P. Hirani, Fiona Kennedy, Nathalie Picaut, Shay Cullen, John E. Deanfield, Stanton P. Newman
Summary: This study compared the health-related quality of life (HRQoL) of people with adult congenital heart disease (ACHD) with the general population and among 4 diagnostic groups. Risk factors for poor HRQoL in ACHD were identified, including younger age, perception of more severe symptoms, depression, and anxiety.
JOURNAL OF CARDIOVASCULAR NURSING
(2023)
Article
Biochemistry & Molecular Biology
Xinlin Chen, Sheng Zhao, Xiaoyan Dong, Juntao Liu, Yulin Guo, Weina Ju, Peiwen Chen, Yanduo Gao, Qian Feng, Xia Zhu, Hui Huang, Xiaojun Lu, Xiaohong Yang, Fan Yang, Chen Cheng, Xishun Luo, Longxian Cheng, Nanbert Zhong
Summary: A national echocardiography screening program for fetal congenital heart defects (CHDs) was conducted in China to assess the incidence, distribution, and disease spectrum of CHDs. Ventricular septal defect was the most common CHD, followed by tetralogy of Fallot. Majority of the CHD cases were isolated intracardiac single defects, while some had multiple heart defects. The central nervous system was the most common extracardiac tissue associated with CHDs, and trisomy 18 was the most common chromosomal abnormality.
CELL AND BIOSCIENCE
(2023)
Article
Pediatrics
Zhimeng Huang, Yue Qiu, Jiawen Qi, Xiaohui Ma, Qiliang Cheng, Jinzhun Wu
Summary: A case-control study conducted in Xiamen, China examined the relationship between common air pollutants and common birth defects. The results showed that exposure to sulfur dioxide significantly increased the risk of congenital heart disease, cleft lip and/or cleft palate, and ear deformity in the first and second months of pregnancy. This study emphasizes the importance of reducing air pollution to prevent birth defects.
FRONTIERS IN PEDIATRICS
(2023)
Article
Cardiac & Cardiovascular Systems
Danielle S. Burstein, Joseph W. Rossano, Heather Griffis, Xuemei Zhang, Rachel Fowler, Benjamin Frischertz, Yuli Y. Kim, JoAnn Lindenfield, Jeremy A. Mazurek, Jonathan B. Edelson, Jonathan N. Menachem
Summary: Limited contemporary data exist regarding outcomes and resource use among adults with congenital heart disease and heart failure. This study compared outcomes and resource use between adults with congenital heart disease and heart failure (ACHD-HF) and non-ACHD with heart failure (HF-non-ACHD). The study found that ACHD-HF patients have increased emergency department and hospital resource use over the past 10 years, but are less likely to receive advanced heart failure therapies such as ventricular assist device (VAD) or transplant compared with non-ACHD heart failure patients.
Article
Cardiac & Cardiovascular Systems
Fan Yang, Jianfang Luo, Qingyi Hou, Nianjin Xie, Zhiqiang Nie, Wenhui Huang, Yuan Liu, Yingling Zhou, Jiyan Chen, Qingshan Geng
JOURNAL OF NUCLEAR CARDIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Xiuting Sun, Yue Guo, Zhiqiang Nie, Jing Cheng, Huimin Zhou, Xiangbin Zhong, Shaozhan Zhang, Zhimin Du, Xiaodong Zhuang, Xinxue Liao
CLINICAL RESEARCH IN CARDIOLOGY
(2019)
Article
Peripheral Vascular Disease
Huanhuan Liu, Xiangmin Gao, Long Zhou, Yong Wu, Ying Li, Jinzhuang Mai, Zhiqiang Nie, Yangfeng Wu, Xiaoqing Liu, Liancheng Zhao
HYPERTENSION RESEARCH
(2018)
Article
Nutrition & Dietetics
Linhui Hu, Zhiqiang Nie, Yichen Zhang, Yanlin Zhang, Heng Ye, Ruibin Chi, Bei Hu, Bo Lv, Lifang Chen, Xiunong Zhang, Huajun Wang, Chunbo Chen
CLINICAL NUTRITION
(2019)
Article
Peripheral Vascular Disease
Haojian Dong, Yanqiu Ou, Zhiqiang Nie, Wenhui Huang, Yuan Liu, Yingling Zhou, Jianfang Luo, Guang Li
Article
Cardiac & Cardiovascular Systems
Pengyu Zhou, Peng Zhu, Zhiqiang Nie, Shaoyi Zheng
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2019)
Article
Cardiac & Cardiovascular Systems
Da-ya Yang, Zhi-qiang Nie, Li-zhen Liao, Shao-zhao Zhang, Hui-min Zhou, Xiu-ting Sun, Xiang-bin Zhong, Zhi-min Du, Xiao-dong Zhuang, Xin-xue Liao
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2019)
Article
Medicine, General & Internal
Tingting Shi, Zhiqiang Nie, Li Huang, Huifeng Fan, Gen Lu, Diyuan Yang, Dongwei Zhang
Article
Nutrition & Dietetics
Yingkai Xiao, Zhimei He, Yi Long, Weisheng Chen, Dezhu Chen, Ruibin Chi, Heng Ye, Xi Deng, Bo Lv, Cheng Sun, Bei Hu, Zhiqiang Nie, Shaodong Gu, Chunbo Chen
CLINICAL NUTRITION
(2020)
Article
Cardiac & Cardiovascular Systems
Hujun Cui, Zhiqiang Nie, Yanqiu Ou, Kan Zhou, Jimei Chen, Jianzheng Cen, Gang Xu, Shusheng Wen, Xiaoqin Liu, Jian Zhuang
JOURNAL OF CARDIAC SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Junfei Zhao, Xiaowei Cai, Yun Teng, Zhiqiang Nie, Yanqiu Ou, Jian Zhuang, Shusheng Wen, Jianzheng Cen, Gang Xu, Hujun Cui, Jimei Chen
JOURNAL OF CARDIAC SURGERY
(2020)
Article
Public, Environmental & Occupational Health
Dylan J. Nagy, David M. Dziewulski, Neculai Codru, Ursula L. Lauper
Summary: The study found that in well-maintained or effectively treated facility water systems, the proportion of positive Legionella samples should be 30% or lower, indicating a problem in the water system if it exceeds that cutoff.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Biology
Yanji Qu, Shao Lin, Michael S. Bloom, Ximeng Wang, Zhiqiang Nie, Yanqiu Ou, Jinzhuang Mai, Xiangmin Gao, Yong Wu, Jimei Chen, John Justino, Hongzhuan Tan, Jian Zhuang, Xiaoqing Liu
Summary: This study aimed to examine the effect modification of maternal risk factor exposures and congenital heart disease (CHD) by maternal folic acid supplementation (FAS)/non-FAS. The results showed significant interactions between maternal FAS/non-FAS and factors like fever, viral infection, and threatened abortion on CHDs. Additionally, non-FAS and living in a newly renovated home also had an impact on CHDs.
Editorial Material
Environmental Sciences
Ursula Lauper, Martin Zartarian, Chelsea Hogan, Braden Savage, David Dziewulski
JOURNAL OF ENVIRONMENTAL HEALTH
(2020)
Article
Cardiac & Cardiovascular Systems
Yanji Qu, Shusheng Wen, Xiaoqing Liu, Wei Pan, Fengzhen Han, Jinzhuang Mai, Yanqiu Ou, Zhiqiang Nie, Xiangmin Gao, Yong Wu, Richard G. Ohye, Jimei Chen, Jian Zhuang
CARDIOLOGY IN THE YOUNG
(2018)
