Article
Food Science & Technology
Yuan Qi, Danyang Wang, Li Fang, Xiaoting Liu, Chunlei Liu, Fanrui Zhao, Dan Wu, Xiyan Wang, Ji Wang, Weihong Min
Summary: This study demonstrated that the exopolysaccharide (EPS103) derived from Lactiplantibacillus plantarum JLAU103 has hypoglycemic, hypolipidemic, and neuroprotective effects in a type 2 diabetes mouse model. EPS103 regulates glucose metabolism pathways, inhibits inflammation, and shows potential as a therapeutic agent for the treatment of type 2 diabetes.
Article
Energy & Fuels
Nazli Pinar Arslan, Handan Cinar-Yilmaz, Dilek Vural-Keles, Meryem Doymus, Ferah Yilmaz, Mesut Taskin
Summary: This study aimed to produce exopolysaccharide (EPS) and mycelial biomass from the edible mushroom Lentinus edodes using peptone prepared from waste sheep wool. Wool peptones were found to be richer in minerals, especially Na and Cl, and more favorable for EPS synthesis compared to commercial peptones. However, commercial peptones resulted in relatively higher mycelial biomass concentrations.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Biochemistry & Molecular Biology
Pin Gong, Xiaojuan Wang, Meng Liu, Mengrao Wang, Siyuan Wang, Yuxi Guo, Xiangna Chang, Wenjuan Yang, Xuefeng Chen, Fuxin Chen
Summary: This study evaluated the hypoglycemic effect of a novel polysaccharide from Lentinus edodes, named LNT-1, on mice with type 2 diabetes. The results showed that LNT-1 treatment improved the damage in diabetic mice, possibly by activating the Nrf2/HO-1 pathway. Metabolomics analysis also identified several metabolic pathways related to the occurrence of diabetes.
Article
Food Science & Technology
Fei Xia, Shiling Cao, Mengwen Wang, Yujiao Sun
Summary: This study comprehensively evaluated the extraction, structural characterization, and hypoglycemic activity of L. edodes polysaccharides. Optimal extraction conditions were determined, and the polysaccharide component LNT was found to have a three-stranded helical structure with a molecular weight of 3.95 x 105 Da and a composition of glucose, galactose, mannose, and arabinose. LNT exhibited significant in vitro hypoglycemic activity and improved insulin resistance by regulating the expression of PI3K and P-AKT proteins in the PI3K/AKT signaling pathway.
Article
Biochemistry & Molecular Biology
Sergio Dantas de Oliveira Junior, Paula Romenya dos Santos Gouvea, Lorena Vieira Bentolila de Aguiar, Vitor Alves Pessoa, Carla Laize dos Santos Cruz Costa, Larissa Ramos Chevreuil, Larissa Batista Dedo BritoNascimento, Everaldo Silvino dos Santos, Ceci Sales-Campos
Summary: This study evaluated the use of lignocellulosic biomass as a substrate in biotechnological processes through solid-state fermentation of Basidiomycete fungi isolated from the Amazon rainforest. The results showed promising potential of agro-industrial residues as an alternative substrate.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Article
Plant Sciences
Adolfo Andrade-Cetto, Fernanda Espinoza-Hernandez, Gerardo Mata-Torres, Sonia Escandon-Rivera
Summary: This study confirmed the traditional use of E. longifolium and A. firma as hypoglycemic agents in a hyperglycemic animal model for the first time. Both plants exhibited a significant hypoglycemic effect and inhibited enzymes involved in glucose metabolism in vitro.
Article
Biochemistry & Molecular Biology
Teng-Gen Hu, Feng-Xiang Tan, Lu Li, Ke-Jing An, Bo Zou, Jing Wen, Ji-Jun Wu, Geng-Sheng Xiao, Yuan-Shan Yu, Yu-Juan Xu
Summary: Litchi polysaccharide Lzp2-2 promotes EPS production by Weissella confusa and improves the viscosity, texture, mouthfeel, and flavor of yoghurt.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Lu Xiao, Wanqian Sha, Chunlin Tao, Chuanli Hou, Ganhong Xiao, Jiaoyan Ren
Summary: This study compared the effects of different drying techniques on the purine content of Lentinus edodes (LE) and found that freeze-drying significantly reduced purine content, making it suitable for consumption by individuals with hyperuricemia and gout.
Article
Biochemistry & Molecular Biology
Wei Xia, Jin Han, Shiming Zhu, Yilin Wang, Wenqing Zhang, Zhengjun Wu
Summary: EPS53, a homogeneous exopolysaccharide (EPS), was isolated from Streptococcus thermophiles XJ53 fermented in skimmed milk and had a high molecular weight and a specific repeating structural unit. EPS53-D, obtained by deproteinization using TCA, had a lower molecular weight but the same repeating structural unit. EPS53 exhibited stronger immune activity than EPS53-D, indicating the importance of molecular weight in EPS activity. TCA treatment may affect the activities of native EPSs produced by fermentation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Amanda Mota Vieira, Farrah Zahed, Alessandre Carmo Crispim, Edson de Souza Bento, Rafael de Freitas Oliveira Franca, Irapuan Oliveira Pinheiro, Luis A. Pardo, Bruno Melo Carvalho
Summary: The study found that high yield of levan was obtained through sucrose fermentation, and treatment with 1000 ug/mL of levan induced apoptosis in neuroblastoma cells without reducing proliferation or causing cytotoxic effects.
CARBOHYDRATE POLYMERS
(2021)
Review
Biochemistry & Molecular Biology
Beatriz Isabel Garcia-Martinez, Mirna Ruiz-Ramos, Jose Pedraza-Chaverri, Edelmiro Santiago-Osorio, Victor Manuel Mendoza-Nunez
Summary: Resveratrol has the potential to improve glucose and insulin levels in patients with type 2 diabetes, with significant improvement in glucose observed at doses of 500-1000 mg/day, and improvement in insulin seen at doses lower than 500 mg/day or greater than 1000 mg/day.
Review
Pharmacology & Pharmacy
Sikai Chen, Miaomiao Xi, Feng Gao, Min Li, TaiWei Dong, Zhixin Geng, Chunyu Liu, Fengyu Huang, Jing Wang, Xingyu Li, Peifeng Wei, Feng Miao
Summary: The effectiveness of herbal medicine in treating diabetes has grown, but the precise mechanism is still unclear. Mulberry leaf, a commonly used herb in traditional Chinese medicine, has been found to have strong anti-diabetic properties. The bioactive compounds in mulberry leaves, such as flavonoids and polysaccharides, play a crucial role in regulating blood glucose levels and improving insulin resistance.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Multidisciplinary Sciences
Masoud Hamidi, Oseweuba Valentine Okoro, Giuseppe Ianiri, Hafez Jafari, Khodabakhsh Rashidi, Saeed Ghasemi, Raffaello Castoria, Davide Palmieri, Cedric Delattre, Guillaume Pierre, Mahta Mirzaei, Lei Nie, Hadi Samadian, Amin Shavandi
Summary: This study characterized and evaluated the biological properties of exopolysaccharides (EPS) produced by the yeast Papiliotrema terrestris PT22AV. The EPS showed potential antibacterial activity and wound healing capacity, making it a promising material for skin wound healing.
JOURNAL OF ADVANCED RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Yunchao Wa, Chenchen Zhang, Gulin Sun, Hengxian Qu, Dawei Chen, Yujun Huang, Ruixia Gu
Summary: Increasing the concentrations of histidine, isoleucine, and glutamate can significantly enhance the production of free exopolysaccharide (f-EPS) and the viability of Streptococcus thermophilus cells. This increase is achieved by up-regulating the transcription of EPS biosynthesis genes and enhancing the activity of key enzymes involved in sugar nucleotide synthesis. Furthermore, the higher concentrations of histidine, isoleucine, and glutamate result in increased lactose consumption and decreased galactose secretion, indicating the improved production of f-EPS.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Fengshu Li, Xin Hu, Liying Qin, Haoshuai Li, Yan Yang, Xiuli Zhang, Jinren Lu, Yiming Li, Mutai Bao
Summary: A novel EPS was isolated from Bacillus sp. QDR3-1 and its structure and repair ability against UVR-mediated cell damage were studied. The results showed that EPS-M1 had good biocompatibility and could mitigate UVR-mediated cell damage.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Burcu Altinay, Ayse Betul Karaduman, Bukay Yenice Gursu, Mustafa Yamac
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
(2015)
Article
Biochemical Research Methods
Burcu Atli, Mustafa Yamac, Zeki Yildiz, Omoanghe S. Isikhuemhen
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
(2016)
Article
Mycology
Burcu Atli, Mustafa Yamac, Zeki Yildiz, Omoanghe S. Isikhuemnen
REVISTA IBEROAMERICANA DE MICOLOGIA
(2015)
Article
Biochemistry & Molecular Biology
Mustafa Yamac, Melih Zeytinoglu, Hakan Senturk, Kazim Kartkaya, Gungor Kanbak, Gokhan Bayramoglu, Aysegul Oglakci, Leo J. L. D. Van Griensven
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
(2016)
Article
Food Science & Technology
Mustafa Uyanoglu, Mediha Canbek, Leo J. L. D. van Griensven, Mustafa Yamac, Hakan Senturk, Kazim Kartkaya, Aysegul Oglakci, Ozge Turgak, Gungor Kanbak
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2014)
Article
Biochemistry & Molecular Biology
Burcu Atli, Mustafa Yamac
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
(2012)
Article
Chemistry, Physical
Fati Karci, Fikret Karci, Aykut Demircali, Mustafa Yamac
JOURNAL OF MOLECULAR LIQUIDS
(2013)
Article
Plant Sciences
Fatma Ozgul Ozalp, Mediha Canbek, Mustafa Yamac, Gungor Kanbak, Leo J. L. D. Van Griensven, Mustafa Uyanoglu, Hakan Senturk, Kazim Kartkaya, Aysegul Oglakci
PHARMACEUTICAL BIOLOGY
(2014)
Article
Chemistry, Multidisciplinary
Mohammad Shakhawoat Hossain, Sidika Polat Cakir, Ayse Betul Karaduman, Mustafa Yamac, Ayhan Sitki Demir
TURKISH JOURNAL OF CHEMISTRY
(2014)
Article
Microscopy
Mustafa Uyanoglu, Mustafa Yamac, Mediha Canbek, Hakan Senturk, Kazim Kartkaya, Aysegul Oglakci, Ozge Turgak, Gungor Kanbak
ULTRASTRUCTURAL PATHOLOGY
(2013)
Article
Environmental Sciences
C. Bayburt, A. B. Karaduman, B. Yenice Gursu, M. Tuncel, M. Yamac
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Burcu Atli, Mustafa Yamac, Zeki Yildiz
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
(2013)
Article
Plant Sciences
Ayse Betul Karaduman, Burcu Atli, Mustafa Yamac
TURKISH JOURNAL OF BOTANY
(2012)
Article
Environmental Sciences
Ayse Betul Karaduman, Mustafa Yamac, Zerrin Pat, Maria Julia Amoroso, Sergio Antonio Cuozzo
ENVIRONMENTAL ENGINEERING AND MANAGEMENT JOURNAL
(2011)
Article
Biology
Mustafa Yamac, Kamil Isik, Nevzat Sahin
TURKISH JOURNAL OF BIOLOGY
(2011)
