Autophagy in renal diseases

Programmed Necrosis in the Cross Talk of Cell Death and Inflammation

(2015) Francis Ka-Ming Chan et al.   Annual Review of Immunology

The dual role of autophagy under hypoxia-involvement of interaction between autophagy and apoptosis

(2015) Mengmeng Li et al.   APOPTOSIS

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

(2015) G. Napolitano et al.   EMBO Molecular Medicine

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

(2015) Manuele Rebsamen et al.   NATURE

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

(2015) S. Wang et al.   SCIENCE

Beneficial Effects of AMP-Activated Protein Kinase Agonists in Kidney Ischemia-Reperfusion: Autophagy and Cellular Stress Markers

(2015) Anne-Emilie Declèves et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Autophagy: Basic Principles and Relevance to Transplant Immunity

(2014) P. Bizargity et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Autophagy in Renal Ischemia-Reperfusion Injury: Friend or Foe?

(2014) J. P. Decuypere et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Transient increase in proteinuria, poly-ubiquitylated proteins and ER stress markers in podocyte-specific autophagy-deficient mice following unilateral nephrectomy

(2014) Juan Alejandro Oliva Trejo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and regulation of cilia function and assembly

(2014) I Orhon et al.   CELL DEATH AND DIFFERENTIATION

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Polycystin-1 Negatively Regulates Polycystin-2 Expression via the Aggresome/Autophagosome Pathway

(2014) Valeriu Cebotaru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Die another way – non-apoptotic mechanisms of cell death

(2014) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS

(2014) T. Kawakami et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of Intracellular Clusterin Attenuates Cell Death in Nephropathic Cystinosis

(2014) P. Sansanwal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mechanisms and biological functions of autophagy in diseased and ageing kidneys

(2014) Sophie Fougeray et al.   Nature Reviews Nephrology

mTOR controls kidney epithelia in health and disease

(2014) F. Grahammer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Direct recording and molecular identification of the calcium channel of primary cilia

(2013) Paul G. DeCaen et al.   NATURE

Primary cilia are specialized calcium signalling organelles

(2013) Markus Delling et al.   NATURE

Functional interaction between autophagy and ciliogenesis

(2013) Olatz Pampliega et al.   NATURE

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

(2013) Zaiming Tang et al.   NATURE

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dysregulated Autophagy Contributes to Podocyte Damage in Fabry’s Disease

(2013) Max C. Liebau et al.   PLoS One

mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

(2013) Jean-Paul Decuypere et al.   PLoS One

GATORs Take a Bite Out of mTOR

(2013) R. J. Shaw   SCIENCE

Autophagy in Acute Kidney Injury

(2013) Man J. Livingston et al.   SEMINARS IN NEPHROLOGY

mTOR Signaling in Autophagy Regulation in the Kidney

(2013) Ken Inoki   SEMINARS IN NEPHROLOGY

Emerging Roles of Autophagy in the Stressed Kidney Allograft

(2013) Nicolas Pallet   SEMINARS IN NEPHROLOGY

Autophagy: Emerging Therapeutic Target for Diabetic Nephropathy

(2013) Shinji Kume et al.   SEMINARS IN NEPHROLOGY

Polycystic Kidney Disease: A Case of Suppressed Autophagy?

(2013) Kameswaran Ravichandran et al.   SEMINARS IN NEPHROLOGY

Introduction: Autophagy in Kidneys

(2013) Zheng Dong   SEMINARS IN NEPHROLOGY

Autophagy in Glomerular Health and Disease

(2013) Björn Hartleben et al.   SEMINARS IN NEPHROLOGY

Regulation of Autophagy by TGF-β: Emerging Role in Kidney Fibrosis

(2013) Yan Ding et al.   SEMINARS IN NEPHROLOGY

Chaperone-Mediated Autophagy in the Kidney: The Road More Traveled

(2013) Harold A. Franch   SEMINARS IN NEPHROLOGY

Nutrient signaling to mTOR and cell growth

(2013) Jenna L. Jewell et al.   TRENDS IN BIOCHEMICAL SCIENCES

Emerging role of autophagy in kidney function, diseases and aging

(2012) Tobias B. Huber et al.   Autophagy

Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury

(2012) Shuya Liu et al.   Autophagy

Polycystins and cellular Ca2+ signaling

(2012) D. Mekahli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury

(2012) Shunsaku Nakagawa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

p62/SQSTM1 prominently accumulates in renal proximal tubules in nephropathic cystinosis

(2012) Poonam Sansanwal et al.   PEDIATRIC NEPHROLOGY

Proton-Assisted Amino Acid Transporter PAT1 Complexes with Rag GTPases and Activates TORC1 on Late Endosomal and Lysosomal Membranes

(2012) Margrét H. Ögmundsdóttir et al.   PLoS One

Chaperone-mediated autophagy: a unique way to enter the lysosome world

(2012) Susmita Kaushik et al.   TRENDS IN CELL BIOLOGY

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

A comprehensive glossary of autophagy-related molecules and processes (2ndedition)

(2011) Daniel J Klionsky et al.   Autophagy

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

A dual role for Ca2+ in autophagy regulation

(2011) Jean-Paul Decuypere et al.   CELL CALCIUM

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Microautophagy: lesser-known self-eating

(2011) Wen-wen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

(2011) T. Kimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Autophagy Is a Renoprotective Mechanism During in Vitro Hypoxia and in Vivo Ischemia-Reperfusion Injury

(2010) Man Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Abnormal mitochondrial autophagy in nephropathic cystinosis

(2010) Poonam Sansanwal et al.   Autophagy

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

(2010) Hannah E.J. Polson et al.   Autophagy

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Structural Conservation of Components in the Amino Acid Sensing Branch of the TOR Pathway in Yeast and Mammals

(2010) Konstantin Kogan et al.   JOURNAL OF MOLECULAR BIOLOGY

Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD

(2010) S. J. Leuenroth et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Autophagy Promotes Cellular Injury in Nephropathic Cystinosis

(2009) P. Sansanwal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxic preconditioning reinforces HIF-alpha-dependent HSP70 signaling to reduce ischemic renal failure-induced renal tubular apoptosis and autophagy

(2009) Chung-Hsin Yeh et al.   LIFE SCIENCES

Bcl-2 Protects Tubular Epithelial Cells From Ischemia/Reperfusion Injury by Dual Mechanisms

(2009) Y. Isaka et al.   TRANSPLANTATION PROCEEDINGS

Urinary Protein Excretion Pattern and Renal Expression of Megalin and Cubilin in Nephropathic Cystinosis

(2008) Martijn J. Wilmer et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Participation of autophagy in renal ischemia/reperfusion injury

(2008) Chigure Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Self-eating from an ER-associated cup: Figure 1.

(2008) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY