Article
Multidisciplinary Sciences
Yumiko Yamazaki, Shigeharu Moriya, Shinpei Kawarai, Hidetoshi Morita, Takefumi Kikusui, Atsushi Iriki
Summary: This study examined the effect of enhanced insect feeding on the gut of common marmosets by analyzing their fecal microbiota and transcripts. The results showed differential characteristics in the microbiota and significant changes in transcripts with insect feeding treatment, indicating a functional correlation or interaction between the two.
Article
Audiology & Speech-Language Pathology
Chenggang Chen, Evan D. Remington, Xiaoqin Wang
Summary: The common marmoset is used as a model in auditory neuroscience due to its ability to localize sounds. However, little is known about the sound localization behavior of marmosets. This study measured the sound localization acuity of marmosets and found that they have similar spatial acuity to other species of similar head size and field of best vision.
Article
Immunology
Michelle Nelson, Francisco J. Salguero, Laura Hunter, Timothy P. Atkins
Summary: Common marmosets were susceptible to inhalational infection with Coxiella burnetii in a dose-dependent manner, producing a disease similar to human Q fever. The illness was characterized by febrile response, weight loss, liver enzyme dysfunction, circulating INF-gamma and bacteraemia. Histological evidence showed macrophage and lymphocyte infiltration into the lung resulting in granulomatous alveolitis.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Biology
Lina Kloesener, Sabine Samolovac, Ina Barnekow, Jessica Koenig, Amir Moussavi, Susann Boretius, Dieter Fuchs, Astrid Haegens, Rabea Hinkel, Matthias Mietsch
Summary: Appropriate cardiovascular animal models are urgently needed to investigate genetic, molecular, and therapeutic approaches, yet the translational gap between currently used animal species and humans remains. The common marmoset is a potential candidate for cardiovascular research, but its basic hemodynamic system characterization is still lacking. Therefore, functional analyses involving pressure-volume loops, MRI, and echocardiography were performed on common marmosets, providing valuable insights on cardiac function and potential disease alterations through load-independent parameters.
Article
Multidisciplinary Sciences
Michael S. Osmanski, Xiaoqin Wang
Summary: How humans and animals categorize sensory information into behaviorally meaningful categories is a fundamental question in neuroscience. By studying common marmosets, researchers have found that they perceptually categorize their vocalizations and have differential sensitivity to acoustic features of their most common call types. These findings reveal the categorical vocal perception specialization in a New World primate species and provide a basis for future studies on their underlying neural mechanisms.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Multidisciplinary Sciences
Michaela Masilkova, David Boukal, Hayley Ash, Hannah M. Buchanan-Smith, Martina Konecna
Summary: Animal personality can affect reproductive performance, as demonstrated in captive common marmosets. Female personality traits significantly influence inter-birth intervals and fecundity rates, while male traits have limited effects on reproductive success.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Vanessa De Castro, Pascal Girard
Summary: Episodic memory decline is identified as an early sign of cognitive aging in humans, and this study examines whether similar decline occurs in aging marmosets. By implementing a naturalistic approach with young and old marmosets, the research found a decline in the recall of what-when and what-where components of episodic-like memory in aged marmosets.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Vedrana Slipogor, Christina Graf, Jorg J. M. Massen, Thomas Bugnyar
Summary: Consistent inter-individual variation in cognition is influenced by both personality and social environment.
SCIENTIFIC REPORTS
(2022)
Article
Ecology
Maria Fernanda De la Fuente, Cedric Sueur, Paul A. Garber, Julio Cesar Bicca-Marques, Antonio Souto, Nicola Schiel
Summary: Within-group competition over food resources can be a major cost of social living, and exhibiting prosocial behaviors can benefit group members by developing affiliative social relationships and maximizing fitness. This study on common marmosets shows that food availability influences social tolerance and foraging association networks, with individuals adjusting partner choices and association strength in response to food availability. Additionally, social tolerance at feeding sites increases during conditions of expected contest competition, suggesting mutual benefits from maintaining affiliative relationships in cooperative breeding primates.
JOURNAL OF ANIMAL ECOLOGY
(2022)
Article
Cell Biology
Ha Young Jang, Chang Sik Cho, Young Mi Shin, Jina Kwak, Young Hoon Sung, Byeong-Cheol Kang, Jeong Hun Kim
Summary: This study investigated the mechanisms underlying retinal pigment epithelium dysfunction in aging and age-related macular degeneration (AMD) using primary marmoset cells. Comparisons were made between the effects of fetal bovine serum (FBS) and serum-free supplements on cell characteristics, and age-related morphological changes were assessed. The results suggest that primary marmoset RPE cells provide a reliable in vitro model for developing therapeutics for AMD.
Article
Behavioral Sciences
Melise Edwards, Sam Lam, Ravi Ranjan, Mariana Pereira, Courtney Babbitt, Agnes Lacreuse
Summary: Aromatase inhibitors (AIs) are commonly used drugs for treating estrogen receptor (ER)-dependent breast cancers, but they can cause adverse effects. Previous studies in marmosets have shown that AIs can replicate these negative effects and increase estradiol levels in the hippocampus. RNA-sequencing analysis revealed that AIs may differentially affect males and females, potentially through processes mediated by the CYP450 superfamily.
HORMONES AND BEHAVIOR
(2023)
Article
Multidisciplinary Sciences
Alexander Weiss, Chihiro Yokoyama, Takuya Hayashi, Miho Inoue-Murayama
Summary: Studies of personality traits in common marmosets reveal factors such as Sociability, Dominance, Neuroticism, Openness, and Impulsiveness, with higher-order factors of Pro-sociality and Boldness. Relationships between personality factors and well-being align with definitions, but there is no significant association between personality and genotype. The structure of common marmoset personality appears to vary depending on rearing or housing conditions that require further investigation.
Article
Multidisciplinary Sciences
Alexander Sheh, Stephen C. Artim, Monika A. Burns, Jose Arturo Molina-Mora, Mary Anne Lee, Joann Dzink-Fox, Sureshkumar Muthupalani, James G. Fox
Summary: This study characterizes the gut microbiome of healthy captive marmosets and marmosets with inflammatory bowel disease (IBD). It shows that marmosets with IBD have decreased alpha diversity and a shift in the ratio of Bacteroides:Prevotella copri compared to healthy marmosets. The study also demonstrates that source-specific microbiomes can be retained despite standardized diets and husbandry practices in marmosets.
SCIENTIFIC REPORTS
(2022)
Article
Geriatrics & Gerontology
Carmen Freire-Cobo, Emily S. Rothwell, Merina Varghese, Melise Edwards, William G. M. Janssen, Agnes Lacreuse, Patrick R. Hof
Summary: The investigation focuses on the neurobiological and neuropathological changes in synapses and their impact on the vulnerability of the aging brain to Alzheimer's disease. Cellular characteristics in the cerebral cortex of behaviorally characterized marmosets were studied, revealing increased astrogliosis, heightened phagocytic activity of microglial cells, and differences in microglial cell phenotypes between cognitively impaired and non-impaired marmosets. Additionally, age-related changes in dendritic spines were observed in cortical areas associated with cognition. These findings suggest an accelerated aging process and neurodegeneration contributing to neuronal vulnerability in cognitively impaired aged marmosets.
NEUROBIOLOGY OF AGING
(2023)
Article
Multidisciplinary Sciences
Michaela Masilkova, Vedrana Slipogor, Guilherme Henrique Lima Marques Silva, Magdalena Hadova, Stanislav Lhota, Thomas Bugnyar, Martina Konecna
Summary: This study investigates the proximate mechanisms underlying animal personalities and suggests that brain lateralization may be one of these mechanisms. The study measures brain lateralization in common marmosets through hand preference testing and evaluates personality through coding observed behaviors. The results reveal three personality dimensions and show that age, rather than hand preference or sex, significantly predicts personality scores. The link between brain lateralization and personality remains equivocal and dependent on assessment methods.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Review
Veterinary Sciences
Taeho Kwon
Summary: Global viral outbreaks and diseases have had significant impacts on human health. Understanding disease mechanisms and developing effective vaccines and treatments are crucial. Non-human primates play a vital role as animal models, due to their evolutionary and physiological similarities to humans.
JOURNAL OF MEDICAL PRIMATOLOGY
(2024)