Article
Infectious Diseases
Robert E. Rollins, Zehra Yeyin, Maja Wyczanska, Nikolas Alig, Sabrina Hepner, Volker Fingerle, Gabriele Margos, Noemie S. Becker
Summary: The study found Borrelia burgdorferi s. l. positive ticks in all plots around Munich, Germany, with significantly different numbers of positive nymphs between plots but not for positive adults. Six Bbsl genospecies were identified, with B. afzelii and B. garinii dominating and B. miyamotoi found in two sampling plots, highlighting variability in Bbsl prevalence and genospecies distribution over short geographic distances.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Infectious Diseases
Derick Thompson, John A. Watt, Catherine A. Brissette
Summary: The text discusses the host immune and inflammatory response induced by Lyme borreliosis bacterium and how these responses influence the pathology of Lyme disease.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Immunology
Tian-Le Che, Bao-Gui Jiang, Qiang Xu, Yu-Qi Zhang, Chen-Long Lv, Jin-Jin Chen, Ying-Jie Tian, Yang Yang, Simon I. Hay, Wei Liu, Li-Qun Fang
Summary: This study established a nationwide database involving Lyme borreliosis risk factors in China and used a two-stage statistical model to identify the environmental factors influencing its distribution. By mapping the risk distribution, it was found that high-risk areas were not only concentrated in high latitude regions but also distributed in middle and low latitude areas.
EMERGING MICROBES & INFECTIONS
(2022)
Article
Clinical Neurology
Ilse M. Lucke, Amber Vrijlandt, Johan Lim, Anneke J. Kooi, Ivo N. Schaik, Hans L. Zaaijer, Joppe W. Hovius, Filip Eftimov
Summary: This study found that apparent Bbsl seroconversion often occurs in patients receiving IVIg treatment, but antibodies typically disappear post-treatment, with seroreversion observed in a majority of patients within 3 months. The transient presence of anti-Bbsl IgG antibodies after IVIg treatment appears to be dependent on the brand of IVIg, reflecting variations in Bbsl exposure of plasma donors. Lyme borreliosis serological testing during and after IVIg treatment may be of limited utility.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Green & Sustainable Science & Technology
Marko Vucelja, Stjepan Krcmar, Josipa Habus, Vesna Mojcec Perko, Marko Boljfetic, Linda Bjedov, Josip Margaletic
Summary: This study investigated the altitudinal distributions, population structures, and seasonal dynamics of tick fauna in three localities in Continental Croatia (Medvednica and Papuk) and an alpine biogeographic region (Gorski Kotar). Questing ticks were sampled twice a year (spring and autumn, from 2019 to 2021) at different altitudes using the flagging method. The majority of the ticks were identified as Ixodes ricinus, with the highest tick abundance observed at higher altitudes in mixed forests of European beech and European silver fir. Borrelia burgdorferi sensu lato infection was detected in a small percentage of ticks, with the presence of the Borrelia burgdorferi sensu stricto genotype.
Article
Parasitology
Zsuzsa Kalmar, Violeta Briciu, Mircea Coroian, Mirela Flonta, Amanda-Lelia Radulescu, Adriana Topan, Andrei Daniel Mihalca, Mihaela Lupse
Summary: The study in Romania found specific IgG and IgM antibodies to Borrelia burgdorferi s.l. among healthy blood donors. Higher seroprevalence was observed in men, older individuals, and those engaged in outdoor work.
PARASITES & VECTORS
(2021)
Article
Infectious Diseases
Mateusz Markowicz, Michael Kundi, Gerold Stanek, Hannes Stockinger
Summary: The relationship between infection with Borrelia burgdorferi sensu lato and nonspecific symptoms is controversial. This study found that individuals infected with B. burgdorferi sl did not develop nonspecific symptoms more frequently compared to non-infected controls.
TICKS AND TICK-BORNE DISEASES
(2022)
Article
Infectious Diseases
Yekaterina O. Ostapchuk, Yuliya Perfilyeva, Andrey Zhigailov, Elina R. Maltseva, Alena S. Neupokoyeva, Akerke O. Bissenbay, Zhanna A. Berdygulova, Dinara A. Naizabayeva, Anna S. Nizkorodova, Zhanna Zh Shapiyeva, Ravilya A. Yegemberdiyeva, Tatyana Kuznetsova, Saltanat Kuatbekova, Assiya Akanova, Gulnara A. Ismagulova, Seidigapbar M. Mamadaliyev, Andrey M. Dmitrovskiy, Yuriy A. Skiba
Summary: Lyme borreliosis is common in Kazakhstan, especially in the Almaty oblast, with evidence of active circulation of Borrelia burgdorferi s.l. The study found a 24% prevalence rate of B. burgdorferi s.l. in Ixodes persulcatus ticks that attacked humans, as well as a 5.8% seroprevalence rate of antibodies against B. burgdorferi s.l. in the local population. These results highlight the importance of LB preventive measures in the region.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Microbiology
Zhihai He, Baogui Jiang, Lin Huang, Zongti Shao, Yun Zhang, Yuqiong Li, Ennian Pu, Xingde Duan, Hang Jiang, Jian Wang, Mingguo Yao, Fan Wang, Shuangshuang Bie, Michael E. von Fricken, Yi Sun, Yi Dong, Jiafu Jiang, Chunhong Du
Summary: This study conducted a comprehensive investigation of Borrelia burgdorferi sensu lato (BBSL) in reservoirs and vectors in Yunnan Province, China. The results revealed a wide distribution of BBSL and multiple endemic genospecies, highlighting the need for expanded surveillance efforts for human in southwestern China.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Veterinary Sciences
Sophie Charlotte Doff, Jasmin Wenderlein, Anna Wiesinger, Stephanie Hiereth, Sebastian Ulrich, Reinhard K. Straubinger
Summary: In this study, two different line immunoassays (LIAs) were compared for the detection of Lyme borreliosis in dogs and horses. The results showed that both LIAs were reliable for canine serum samples, but there were still challenges in diagnosing equine serum samples.
VETERINARY SCIENCES
(2022)
Article
Microbiology
Cristian Raileanu, Cornelia Silaghi, Volker Fingerle, Gabriele Margos, Claudia Thiel, Kurt Pfister, Evelyn Overzier
Summary: The study demonstrates high infection levels and diverse genospecies of Borrelia in questing ticks in different habitats in Southern Germany. The presence of roe deer appears to reduce infection rates of B. burgdorferi s.l. in tick populations.
Article
Infectious Diseases
Lynn M. Osikowicz, Maria R. Rizzo, Andrias Hojgaard, Sarah E. Maes, Rebecca J. Eisen
Summary: This article describes the prevalence and diversity of Lyme disease in the United States. By using different detection methods, the authors found various species of spirochetes present in specific tick species, revealing the potential transmission of pathogens among ticks.
TICKS AND TICK-BORNE DISEASES
(2024)
Article
Microbiology
Barbara C. Weck, Maria Carolina A. Serpa, Marcelo B. Labruna, Sebastian Munoz-Leal
Summary: A new genospecies of Borrelia, named Candidatus Borrelia paulista Rp42, was discovered in small mammals in Brazilian forests. This genospecies is phylogenetically related to a Borrelia genospecies in North America. Further research is needed to confirm whether the tick species found in the same area could be a potential host for this novel Borrelia species.
Review
Microbiology
Klaus-Peter Hunfeld, Peter Kraiczy, Douglas E. Norris, Benedikt Lohr
Summary: Lyme borreliosis is a multisystem disorder caused by the spirochete Borrelia burgdorferi sensu lato, transmitted by hard ticks of the Ixodes ricinus complex. Although the full spectrum of in vitro antibiotic susceptibility for some recently developed compounds is still not defined, our current understanding of the in vitro interactions between B. burgdorferi s. l. and antimicrobial agents and their mechanisms of resistance remains limited, largely based on a few isolates of Borrelia.
Article
Biochemistry & Molecular Biology
Robert E. Rollins, Kozue Sato, Minoru Nakao, Mohammed T. Tawfeeq, Fernanda Herrera-Mesias, Ricardo J. Pereira, Sergey Kovalev, Gabriele Margos, Volker Fingerle, Hiroki Kawabata, Noemie S. Becker
Summary: Vector-borne pathogens can expand geographically and cause new diseases through host and vector shifts. In this study, the evolutionary history of three Borrelia genospecies was reconstructed using 142 Eurasian isolates, and it was found that each genospecies has an Asian origin but displayed unique substructuring and evolutionary response to the colonization of Europe. The pattern of allele sharing between continents supports the concept of host adaptation being important for pathogen dispersal.
Article
Microbiology
Brian F. Leydet, Fang Ting Liang
Article
Medicine, General & Internal
Kerry L. Clark, Brian Leydet, Shirley Hartman
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2013)
Article
Entomology
Brian F. Leydet, Fang-Ting Liang
JOURNAL OF MEDICAL ENTOMOLOGY
(2014)
Article
Infectious Diseases
Brian F. Leydet, Fang-Ting Liang
TICKS AND TICK-BORNE DISEASES
(2013)
Article
Public, Environmental & Occupational Health
Lorne Farovitch, Rachel Sippy, Efrain Beltran-Ayala, Timothy P. Endy, Anna M. Stewart-Ibarra, Andbrian F. Leydet
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2019)
Article
Fisheries
Benjamin D. Gallo, John M. Farrell, Brian F. Leydet
Article
Multidisciplinary Sciences
Benjamin D. Gallo, John M. Farrell, Brian Leydet
Article
Marine & Freshwater Biology
Benjamin D. Gallo, John M. Farrell, Brian F. Leydet
Summary: Diet plays a critical role in the composition and development of the gut microbiome in fish. Our study found that the initial diet has a strong influence on the gut microbiome structure of fish later in life.