4.3 Article

Brain and lung metastasis of alveolar echinococcosis in a refugee from a hyperendemic area

Journal

JOURNAL OF MEDICAL MICROBIOLOGY
Volume 57, Issue 11, Pages 1420-1423

Publisher

MICROBIOLOGY SOC
DOI: 10.1099/jmm.0.2008/002816-0

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Alveolar echinococcosis (AE) of the liver with cerebral and pulmonary metastasis was diagnosed in a Tibetan monk who initially presented with severe headache to an emergency department in Germany. Multiple lesions with perifocal oedema and severe compression of the third ventricle were seen with computed tomography (CT) of the brain. Glioma or cerebral metastasis of a hitherto undiagnosed abdominal or pulmonary malignancy was suspected. CT scans of the lung and liver demonstrated further tumorous masses. Magnetic resonance imaging of the brain revealed the cystic nature of the cerebral lesions and the patient had a highly positive serology for AE. The echinococcal aetiology of the brain lesions was confirmed by PCR for this refugee from an area where two disease entities, AE and cystic echinococcosis, are hyperendemic.

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