TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephaly

A High-Throughput Quantitative Approach Reveals More Small RNA Modifications in Mouse Liver and Their Correlation with Diabetes

(2013) Menghong Yan et al.   ANALYTICAL CHEMISTRY

Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate

(2013) Zhenhua Shao et al.   NUCLEIC ACIDS RESEARCH

Unexpected expansion of tRNA substrate recognition by the yeast m1G9 methyltransferase Trm10

(2013) W. E. Swinehart et al.   RNA

tRNA Methyltransferase Homolog Gene TRMT10A Mutation in Young Onset Diabetes and Primary Microcephaly in Humans

(2013) Mariana Igoillo-Esteve et al.   PLoS Genetics

Hyperinsulinism Presenting in Childhood and Treatment by Conservative Pancreatectomy

(2012) Mary Patterson et al.   Endocrine Practice

A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase—extensive moonlighting in mitochondrial tRNA biogenesis

(2012) Elisa Vilardo et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

Transfer RNA modifications: nature's combinatorial chemistry playground

(2012) Jane E. Jackman et al.   Wiley Interdisciplinary Reviews-RNA

Single-Molecule FRET Reveals a Cooperative Effect of Two Methyl Group Modifications in the Folding of Human Mitochondrial tRNALys

(2011) Andrei Yu Kobitski et al.   CHEMISTRY & BIOLOGY

Glucose Metabolism in 105 Children and Adolescents After Pancreatectomy for Congenital Hyperinsulinism

(2011) J. Beltrand et al.   DIABETES CARE

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

MutationTaster evaluates disease-causing potential of sequence alterations

(2010) Jana Marie Schwarz et al.   NATURE METHODS

New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA

(2010) M. Kempenaers et al.   NUCLEIC ACIDS RESEARCH

RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme

(2008) Johann Holzmann et al.   CELL

Novel De Novo Mutation in Sulfonylurea Receptor 1 Presenting as Hyperinsulinism in Infancy Followed by Overt Diabetes in Early Adolescence

(2008) M. Abdulhadi-Atwan et al.   DIABETES

Evidence that tRNA modifying enzymes are important in vivo targets for 5-fluorouracil in yeast

(2008) M. Gustavsson et al.   RNA