Mutation inPLK4, encoding a master regulator of centriole formation, defines a novel locus for primordial dwarfism

Genomic analysis of primordial dwarfism reveals novel disease genes

(2014) R. Shaheen et al.   GENOME RESEARCH

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

(2014) Suk-Youl Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles

(2013) Paula A. Coelho et al.   DEVELOPMENTAL CELL

Direct Binding of SAS-6 to ZYG-1 Recruits SAS-6 to the Mother Centriole for Cartwheel Assembly

(2013) Molly M. Lettman et al.   DEVELOPMENTAL CELL

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152

(2013) T.-S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Building a centriole

(2012) Tomer Avidor-Reiss et al.   CURRENT OPINION IN CELL BIOLOGY

A centriolar lifeline

(2012) Renata Basto   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a Polo-like Kinase 4-Dependent Pathway for De Novo Centriole Formation

(2011) Frank Eckerdt et al.   CURRENT BIOLOGY

Mechanisms and pathways of growth failure in primordial dwarfism

(2011) A. Klingseisen et al.   GENES & DEVELOPMENT

Centrosomes and cilia in human disease

(2011) Mónica Bettencourt-Dias et al.   TRENDS IN GENETICS

Novel CENPJ mutation causes Seckel syndrome

(2010) M. S. Al-Dosari et al.   JOURNAL OF MEDICAL GENETICS

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

(2010) Ersan Kalay et al.   NATURE GENETICS

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Primary microcephaly: do all roads lead to Rome?

(2009) Gemma K. Thornton et al.   TRENDS IN GENETICS