4.4 Article

Games of age-dependent prevention of chronic infections by social distancing

Journal

JOURNAL OF MATHEMATICAL BIOLOGY
Volume 66, Issue 7, Pages 1527-1553

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00285-012-0543-8

Keywords

Epidemiological games; Social distancing; Age structure

Funding

  1. National Science Foundation [DMS-0920822]
  2. Bill and Melinda Gates Foundation [49276]
  3. National Institutes of Health [PAR-08-224]
  4. Division Of Mathematical Sciences
  5. Direct For Mathematical & Physical Scien [0920822] Funding Source: National Science Foundation

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Epidemiological games combine epidemic modelling with game theory to assess strategic choices in response to risks from infectious diseases. In most epidemiological games studied thus-far, the strategies of an individual are represented with a single choice parameter. There are many natural situations where strategies can not be represented by a single dimension, including situations where individuals can change their behavior as they age. To better understand how age-dependent variations in behavior can help individuals deal with infection risks, we study an epidemiological game in an SI model with two life-history stages where social distancing behaviors that reduce exposure rates are age-dependent. When considering a special case of the general model, we show that there is a unique Nash equilibrium when the infection pressure is a monotone function of aggregate exposure rates, but non-monotone effects can appear even in our special case. The non-monotone effects sometimes result in three Nash equilibria, two of which have local invasion potential simultaneously. Returning to a general case, we also describe a game with continuous age-structure using partial-differential equations, numerically identify some Nash equilibria, and conjecture about uniqueness.

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