Journal
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
Volume 28, Issue 1, Pages 88-92Publisher
INFORMA HEALTHCARE
DOI: 10.3109/14767058.2014.905907
Keywords
Amniotic fluid; inductively coupled plasma mass spectroscopy; trace elements
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Objective: Knowledge about levels of toxic and non-toxic elements in amniotic fluid is limited. The aims of this study were: (1) to measure levels of trace elements Cu, Fe, Zn, B, Sr and Co in amniotic fluid and maternal serum during second trimester of pregnancy; and (2) to determine what correlations exists between elements levels in amniotic fluid and maternal serum. Methods: The levels of, iron, copper, zinc, cobalt, strontium and boron were measured in blood and amniotic fluid during genetic amniocentesis using inductively coupled plasma mass spectrometry (ICP-MS). Results: Concentrations of the elements: Fe, Cu, Zn, Co, Sr and B in amniotic fluid were significantly lower than in maternal blood. For iron, zinc, cobalt, strontium and boron there was a linear correlation between levels in amniotic fluid and maternal serum. Conclusions: The concentration of trace elements in amniotic fluid was found to be lower than maternal serum and linearly correlated to its level.
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