Journal
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
Volume 23, Issue 5, Pages 399-402Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/14767050903156684
Keywords
Magnesium sulfate; bleeding time; preeclampsia; platelet count; coagulation time
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Methods. During a period of 4 years, 50 patients with severe or mild preeclampsia progressing to severe preeclampsia were included in the cross-sectional study. Prothrombine (PT), activated limited thromboplastin time (aPTT), magnesium level, biochemistry parameters, systolic, and diastolic blood pressure (BP) were measured. These parameters were remeasured in the second hour of magnesium sulfate treatment. Results. After magnesium sulfate therapy; creatinine levels are decreased (p < 0.05), bleeding time is increased and serum magnesium levels are increased (p < 0.01), systolic and diastolic BP values decreased significantly (p < 0.01). PT, aPTT, platelet levels, and coagulation time did not change after treatment. Conclusion. Magnesium sulfate infusion prolonged bleeding time in patients with severe preeclampsia. This is clinically important because it worsens the present condition and causes possible complications.
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