Article
Medicine, General & Internal
Rachel D'Amico, Djhenne Dalmacy, Jenifer A. Akinduro, Madison Hyer, Stephen Thung, Shengyi Mao, Naleef Fareed, Seuli Bose-Brill
Summary: Gestational diabetes (GD) affects pregnancy and increases the risk of type 2 diabetes. The study aimed to explore how often individuals with GD access primary care and type 2 diabetes screening.
Article
Endocrinology & Metabolism
Tina Linder, Anna Eder, Cecile Monod, Ingo Rosicky, Daniel Eppel, Katharina Redling, Franziska Geissler, Evelyn A. Huhn, Irene Hosli, Christian S. Gobl
Summary: This study aimed to evaluate the impact of prepregnancy overweight on treatment modalities and pregnancy outcomes in gestational diabetes mellitus (GDM). The results showed that an increased BMI in pregnant women was associated with a higher likelihood of needing glucose lowering medication and an increased risk of adverse pregnancy outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Environmental Sciences
Kari A. Weber, Wei Yang, Suzan L. Carmichael, R. Thomas Collins, Thomas J. Luben, Tania A. Desrosiers, Tabassum Z. Insaf, Mimi T. Le, Shannon Pruitt Evans, Paul A. Romitti, Mahsa M. Yazdy, Wendy N. Nembhard, Gary M. Shaw
Summary: This study examined the association between maternal residential proximity to greenspace and structural birth defects. The results showed that living closer to greenspace during pregnancy is associated with a reduced risk of certain birth defects, especially among those living in rural or high-income neighborhoods.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Mervat A. AbdRabou, Barakat M. Alrashdi, Hadeel K. Alruwaili, Reda H. Elmazoudy, Maha A. Alwaili, Sarah I. Othman, Fawzyah A. Alghamdi, Gehan H. Fahmy
Summary: This study investigated the potential effects of metronidazole on pregnancy outcomes and found that it can cause hepatotoxicity in pregnant rats, reduce the number of implanted embryos and fetal viability, increase fetal lethality and resorptions, and affect fetal development and placental pathology.
Article
Endocrinology & Metabolism
Rama J. Wahab, Vincent W. V. Jaddoe, Ellis Voerman, George J. G. Ruijter, Janine F. Felix, Linda Marchioro, Olaf Uhl, Engy Shokry, Berthold Koletzko, Romy Gaillard
Summary: Maternal prepregnancy BMI is associated with altered maternal early-pregnancy amino acids, nonesterified fatty acids, phospholipids, and carnitines concentrations. A metabolite profile identified in this study improved the prediction of birthweight in women with a higher prepregnancy BMI compared to glucose and lipid concentrations.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Multidisciplinary Sciences
Penny Lam, Brendan J. Mein, Ronald J. Benzie, John T. Ormerod, Kristy P. Robledo, Emily J. Hibbert, Ralph K. Nanan
Summary: This study analyzed the effects of maternal diabetes mellitus and body mass index on central and peripheral fat accrual in large for gestational age offspring. The results showed that diabetes mellitus was associated with increased abdominal and mid-thigh fat accumulation in fetuses, independent of BMI.
Article
Obstetrics & Gynecology
Jiajin Hu, Yilin Liu, Xiaotong Wei, Lin Li, Ming Gao, Yang Liu, Yanan Ma, Deliang Wen
Summary: The study found that maternal GDM status was associated with infant WFLZ, especially in early infancy or in normal-weight and overweight/obese women. Efforts to prevent GDM in these mothers are recommended to control offspring overweight or obesity.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Endocrinology & Metabolism
Ravi Retnakaran, Chang Ye, Anthony J. Hanley, Philip W. Connelly, Mathew Sermer, Bernard Zinman, Jill K. Hamilton
Summary: Despite reducing birth weight and macrosomia, the treatment of GDM does not have analogous effects on infant adiposity across the 1st year of life.
Article
Obstetrics & Gynecology
Eman M. Alfadhli
Summary: The study found that both obesity and GDM increase the rates of macrosomia and cesarean deliveries, while GDM is associated with a higher likelihood of infants needing neonatal intensive care. The presence of both conditions together results in the highest risk of adverse pregnancy outcomes.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Public, Environmental & Occupational Health
Wentao Yue, Enjie Zhang, Ruixia Liu, Yue Zhang, Chengrong Wang, Shen Gao, Shaofei Su, Xiao Gao, Qingqing Wu, Xiaokui Yang, Aris T. Papageorghiou, Chenghong Yin
Summary: The China Birth Cohort Study is a national study aiming to investigate risk factors for birth defects and develop strategies for their reduction. The study has completed two phases of recruitment and has collected biological samples from participants. The study aims to recruit 500,000 participants by December 2021.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Immunology
English D. Willis, Ann M. Marko, Sonja A. Rasmussen, Maureen McGee, Karen R. Broder, Mona Marin
Summary: The VARIVAX Pregnancy Registry studied women who received VARIVAX vaccine during pregnancy from 1995 to 2013, and found no association between varicella vaccine exposure and congenital varicella syndrome or major birth defects. However, due to small sample sizes, varicella vaccine is still contraindicated during pregnancy.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Clinical Neurology
Shaun Ajinkya, Jonah Fox, Alain Lekoubou
Summary: Research shows that there have been changes in the prescriptions of antiepileptic drugs given to women of childbearing age between 2004 and 2015, with nearly one third being prescribed potentially teratogenic medications. Women aged 25-34 and 35-44 had lower odds of being prescribed teratogenic drugs compared to those aged 15-24.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Obstetrics & Gynecology
Xiao-guang Yin, Peng Wang, Mei-ting Zhou, De-qin Li, Rui-xue Tao, Fang-biao Tao, Yang Wang, Peng Zhu
Summary: The timing of gestational diabetes mellitus (GDM) diagnosis and gestational weight gains (GWG) during pregnancy are associated with the growth trajectory of children from perinatal to early childhood. GDM diagnosed before 26 weeks increases the risk of fetal overgrowth and higher birth weight, as well as higher BMI peak within 48 months. Maternal early GDM diagnosis and excessive gestational weight gains have additive impacts on offspring overgrowth, with higher levels of hsCRP observed in the early EGWG group.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Public, Environmental & Occupational Health
Ya-Hui Chang, Yu-Wen Chien, Chiung-Hsin Chang, Ping-Ling Chen, Tsung-Hsueh Lu, I-Lin Hsu, Chung-Yi Li
Summary: This study investigated the association between maternal exposure to motor vehicle crashes during pregnancy and the risk of adverse neonatal outcomes. The results showed that offspring exposed to maternal MVCs during pregnancy had a higher risk of birth defects, especially in the early stages of pregnancy. Further research is needed to understand the underlying mechanisms linking maternal exposure to MVCs and birth defects.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Xue Liu, Huan Wang, Liu Yang, Min Zhao, Costan G. Magnussen, Bo Xi
Summary: The associations between gestational weight gain (GWG) and adverse birth outcomes are inconclusive. This study examined the associations between maternal GWG and six adverse birth outcomes in a large population. The results showed that pregnant women with GWG below or above guidelines had increased odds of adverse birth outcomes.
FRONTIERS IN NUTRITION
(2022)