Studies on Deimmunization of Antileukaemic L-Asparaginase to have Reduced Clinical Immunogenicity- An in silico Approach

The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells

(2014) W. K. Chan et al.   BLOOD

l-Asparaginase as Potent Anti-leukemic Agent and Its Significance of Having Reduced Glutaminase Side Activity for Better treatment of Acute Lymphoblastic Leukaemia

(2012) L. N. Ramya et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

In silico Engineering of L-Asparaginase to Have Reduced Glutaminase Side Activity for Effective Treatment of Acute Lymphoblastic Leukemia

(2011) Ramya LN et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift

(2011) J. R. Cantor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of Physical Process Conditions for Enhanced Production of Novel Glutaminase-Free L-Asparaginase from Pectobacterium carotovorum MTCC 1428

(2010) Sanjay Kumar et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

(2010) M. N. Offman et al.   BLOOD

L-asparaginase treatment in acute lymphoblastic leukemia

(2010) Rob Pieters et al.   CANCER

Tolerability and Efficacy of L-Asparaginase Therapy in Pediatric Patients With Acute Lymphoblastic Leukemia

(2010) Elizabeth A. Raetz et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing

(2010) Rohan Patil et al.   PLoS One

Development of medium for enhanced production of glutaminase-free l-asparaginase from Pectobacterium carotovorum MTCC 1428

(2009) Sanjay Kumar et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The cross-reactivity of anti-asparaginase antibodies against different l-asparaginase preparations

(2009) Beata Zalewska-Szewczyk et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Immune epitope database analysis resource (IEDB-AR)

(2008) Q. Zhang et al.   NUCLEIC ACIDS RESEARCH

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

(2008) Peng Wang et al.   PLoS Computational Biology

Efficient docking of peptides to proteins without prior knowledge of the binding site

(2002) Csaba Hetényi et al.   PROTEIN SCIENCE