Characteristics of the designer drug and synthetic cannabinoid receptor agonist AM-2201 regarding its chemistry and metabolism

A fast and inexpensive procedure for the isolation of synthetic cannabinoids from ‘Spice’ products using a flash chromatography system

(2012) Bjoern Moosmann et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Analysis of synthetic cannabinoids in “spice-like” herbal highs: snapshot of the German market in summer 2011

(2012) Karoline Simolka et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice

(2012) Carol A. Paronis et al.   BEHAVIOURAL PHARMACOLOGY

The detection of the urinary metabolites of 1-[(5-fluoropentyl)-1H-indol-3-yl]-(2-iodophenyl)methanone (AM-694), a high affinity cannabimimetic, by gas chromatography - mass spectrometry

(2012) Andrej Grigoryev et al.   Drug Testing and Analysis

Detection of urinary metabolites of AM-2201 and UR-144, two novel synthetic cannabinoids

(2012) Tim Sobolevsky et al.   Drug Testing and Analysis

Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1H-indol-3yl]-(4-methylnaphthalen-1-yl)methanone using GC–MS, NMR analysis and a flash chromatography system

(2012) Bjoern Moosmann et al.   FORENSIC SCIENCE INTERNATIONAL

Synthetic cannabinoids in “spice-like” herbal blends: First appearance of JWH-307 and recurrence of JWH-018 on the German market

(2012) Ludger Ernst et al.   FORENSIC SCIENCE INTERNATIONAL

Identification and quantitation of two new naphthoylindole drugs-of-abuse, (1-(5-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone (AM-2202) and (1-(4-pentenyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone, with other synthetic cannabinoids in unregulated “herbal” products circulated in the Tokyo area

(2012) Jun’ichi Nakajima et al.   Forensic Toxicology

Identification of two new-type synthetic cannabinoids, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA), and detection of five synthetic cannabinoids, AM-1220, AM-2233, AM-1241, CB-13 (CRA-13), and AM-1248, as designer drugs in illegal products

(2012) Nahoko Uchiyama et al.   Forensic Toxicology

Detection and Quantification of New Designer Drugs in Human Blood: Part 1 - Synthetic Cannabinoids

(2012) J. Ammann et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

The Identification of the Urinary Metabolites of 3-(4-Methoxybenzoyl)-1-Pentylindole (RCS-4), a Novel Cannabimimetic, by Gas Chromatography-Mass Spectrometry

(2012) P. Kavanagh et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Detection of JWH-018 and JWH-073 by UPLC-MS-MS in Postmortem Whole Blood Casework

(2012) K. G. Shanks et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Analysis of First and Second Generation Legal Highs for Synthetic Cannabinoids and Synthetic Stimulants by Ultra-Performance Liquid Chromatography and Time of Flight Mass Spectrometry

(2012) K. G. Shanks et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Ultra high performance liquid chromatography–electrospray ionization–tandem mass spectrometry screening method for direct analysis of designer drugs, “spice” and stimulants in oral fluid

(2012) Sabina Strano-Rossi et al.   JOURNAL OF CHROMATOGRAPHY A

Determination of 22 synthetic cannabinoids in human hair by liquid chromatography–tandem mass spectrometry

(2012) Melanie Hutter et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Identification and structural characterization of the synthetic cannabinoid 3-(1-adamantoyl)-1-pentylindole as an additive in ‘herbal incense’

(2012) Stefan Kneisel et al.   JOURNAL OF MASS SPECTROMETRY

Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkylindole type present as adulterants in ‘herbal mixtures’ using LC-MS/MS techniques

(2012) M. Hutter et al.   JOURNAL OF MASS SPECTROMETRY

Simultaneous analysis of several synthetic cannabinoids, THC, CBD and CBN, in hair by ultra-high performance liquid chromatography tandem mass spectrometry. Method validation and application to real samples

(2012) A. Salomone et al.   JOURNAL OF MASS SPECTROMETRY

Analysis of 30 synthetic cannabinoids in serum by liquid chromatography-electrospray ionization tandem mass spectrometry after liquid-liquid extraction

(2012) Stefan Kneisel et al.   JOURNAL OF MASS SPECTROMETRY

Tentative identification of phase I metabolites of HU-210, a classical synthetic cannabinoid, by LC–MS/MS

(2012) Unyong Kim et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

(2011) Cindy L. Moran et al.   ANALYTICAL CHEMISTRY

Identification of a Novel Cannabimimetic Phenylacetylindole, Cannabipiperidiethanone, as a Designer Drug in a Herbal Product and Its Affinity for Cannabinoid CB1 and CB2 Receptors

(2011) Nahoko Uchiyama et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Severe Toxicity Following Synthetic Cannabinoid Ingestion

(2011) J. Lapoint et al.   CLINICAL TOXICOLOGY

The detection of the urinary metabolites of 3-[(adamantan-1-yl)carbonyl]-1-pentylindole (AB-001), a novel cannabimimetic, by gas chromatography-mass spectrometry

(2011) Andrej Grigoryev et al.   Drug Testing and Analysis

The emergence and analysis of synthetic cannabinoids

(2011) Simon Hudson et al.   Drug Testing and Analysis

Identification and characterization of JWH-122 used as new ingredient in “Spice-like” herbal incenses

(2011) Ludger Ernst et al.   FORENSIC SCIENCE INTERNATIONAL

Detection and identification of the new potential synthetic cannabinoids 1-pentyl-3-(2-iodobenzoyl)indole and 1-pentyl-3-(1-adamantoyl)indole in seized bulk powders in Hungary

(2011) Péter Jankovics et al.   FORENSIC SCIENCE INTERNATIONAL

Identification of 1-butyl-3-(1-(4-methyl)naphthoyl)indole in a herbal mixture

(2011) F. Westphal et al.   FORENSIC SCIENCE INTERNATIONAL

Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles JWH-210, JWH-122, and JWH-019 as adulterants in illegal products obtained via the Internet

(2011) Jun’ichi Nakajima et al.   Forensic Toxicology

Identification and quantitation of a benzoylindole (2-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone and a naphthoylindole 1-(5-fluoropentyl-1H-indol-3-yl)-(naphthalene-1-yl)methanone (AM-2201) found in illegal products obtained via the Internet and their cannabimimetic effects evaluated by in vitro [35S]GTPγS binding assays

(2011) Jun’ichi Nakajima et al.   Forensic Toxicology

Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Identification and Quantification of JWH-018, JWH-073, JWH-019, and JWH-250 in Human Whole Blood

(2011) S. L. Kacinko et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Analytical Data for Identification of the Cannabimimetic Phenylacetylindole JWH-203

(2011) Monica Bononi et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Synthetic Cannabinoids in Oral Fluid

(2011) C. Coulter et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Chromatography–mass spectrometry studies on the metabolism of synthetic cannabinoids JWH-018 and JWH-073, psychoactive components of smoking mixtures

(2011) Andrej Grigoryev et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Gas and liquid chromatography–mass spectrometry studies on the metabolism of the synthetic phenylacetylindole cannabimimetic JWH-250, the psychoactive component of smoking mixtures

(2011) Andrej Grigoryev et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type and methanandamide in serum and its application to forensic samples

(2011) Sebastian Dresen et al.   JOURNAL OF MASS SPECTROMETRY

Survey of current trends in the abuse of psychotropic substances and plants in Japan

(2011) Ruri Kikura-Hanajiri et al.   Legal Medicine

Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity

(2011) Lisa K. Brents et al.   PLoS One

In vitro phase I metabolism of the synthetic cannabimimetic JWH-018

(2010) Annette Wintermeyer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Screening for the synthetic cannabinoid JWH-018 and its major metabolites in human doping controls

(2010) Ines Möller et al.   Drug Testing and Analysis

Detection of JWH-018 metabolites in smoking mixture post-administration urine

(2010) Tim Sobolevsky et al.   FORENSIC SCIENCE INTERNATIONAL

Chemical analysis of synthetic cannabinoids as designer drugs in herbal products

(2010) Nahoko Uchiyama et al.   FORENSIC SCIENCE INTERNATIONAL

Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in illegal products

(2010) Nahoko Uchiyama et al.   Forensic Toxicology

Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography–tandem mass spectrometry

(2010) Jörg Teske et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds

(2010) Sebastian Dresen et al.   JOURNAL OF MASS SPECTROMETRY

Identification of a Cannabinoid Analog as a New Type of Designer Drug in a Herbal Product

(2009) Nahoko Uchiyama et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Spice: A never ending story?

(2009) Rainer Lindigkeit et al.   FORENSIC SCIENCE INTERNATIONAL

‘Spice’ and other herbal blends: harmless incense or cannabinoid designer drugs?

(2009) Volker Auwärter et al.   JOURNAL OF MASS SPECTROMETRY