Functional Adaptations of the Transcriptome to Mastitis-Causing Pathogens: The Mammary Gland and Beyond

Systems Biology in Immunology: A Computational Modeling Perspective

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Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources

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In depth analysis of genes and pathways of the mammary gland involved in the pathogenesis of bovine Escherichia coli- mastitis

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Transcriptomic analysis of milk somatic cells in mastitis resistant and susceptible sheep upon challenge with Staphylococcus epidermidis and Staphylococcus aureus

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Differential gene expression of the toll-like receptor-4 cascade and neutrophil function in early- and mid-lactating dairy cows

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Prepartum dietary energy intake affects metabolism and health during the periparturient period in primiparous and multiparous Holstein cows1

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The Host Defense Proteome of Human and Bovine Milk

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Association of major histocompatibility complex antigens (BOLA-A) with AI bull progeny test results for mastitis, ketosis and fertility in Norwegian Cattle

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Functional and gene network analyses of transcriptional signatures characterizing pre-weaned bovine mammary parenchyma or fat pad uncovered novel inter-tissue signaling networks during development

(2010) Paola Piantoni et al.   BMC GENOMICS

Escherichia coli infection induces distinct local and systemic transcriptome responses in the mammary gland

(2010) Simone Mitterhuemer et al.   BMC GENOMICS

Predisposition of cows to mastitis in non-infected mammary glands: effects of dietary-induced negative energy balance during mid-lactation on immune-related genes

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Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis

(2010) Kasey M. Moyes et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Invited review: Ruminant ecology and evolution: Perspectives useful to ruminant livestock research and production

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Anaphylatoxin C5a-induced toll-like receptor 4 signaling in bovine neutrophils

(2010) M.G.H. Stevens et al.   JOURNAL OF DAIRY SCIENCE

Immune Cell Location and Function During Post-Natal Mammary Gland Development

(2010) Johanna R. Reed et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Visualizing biological data—now and in the future

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Visualizing genomes: techniques and challenges

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Negative energy balance and hepatic gene expression patterns in high-yielding dairy cows during the early postpartum period: a global approach

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Integrative Systems Biology for Data-Driven Knowledge Discovery

(2010) Casey S. Greene et al.   SEMINARS IN NEPHROLOGY

Mastitis associated transcriptomic disruptions in cattle

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Transcriptional profiling of immune genes in bovine monocyte-derived macrophages exposed to bacterial antigens

(2010) Maria Taraktsoglou et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARγ signaling as potential mechanism for the negative relationships between immune response and lipid metabolism

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Adipose tissue depots of Holstein cows are immune responsive: Inflammatory gene expression in vitro

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A sentinel function for teat tissues in dairy cows: dominant innate immune response elements define early response to E. coli mastitis

(2009) Manuela Rinaldi et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Cytokine and acute phase protein gene expression in repeated liver biopsies of dairy cows with a lipopolysaccharide-induced mastitis

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Analysis of key molecules of the innate immune system in mammary epithelial cells isolated from marker-assisted and conventionally selected cattle

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Binding of different forms of lipopolysaccharide and gene expression in bovine blood neutrophils

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Neutrophil Extracellular Traps: A Strategic Tactic to Defeat Pathogens with Potential Consequences for the Host

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Stat3 and the Inflammation/Acute Phase Response in Involution and Breast Cancer

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Pleiotropic effects of negative energy balance in the postpartum dairy cow on splenic gene expression: repercussions for innate and adaptive immunity

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Negative energy balance alters global gene expression and immune responses in the uterus of postpartum dairy cows

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Expression of bovine granulocyte chemotactic protein-2 (GCP-2) in neutrophils and a mammary epithelial cell line (MAC-T) in response to various bacterial cell wall components

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Metabolic factors affecting the inflammatory response of periparturient dairy cows

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Gene expression profiling of liver from dairy cows treated intra-mammary with lipopolysaccharide

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Meta Analysis of Gene Expression Data within and Across Species

(2008) Ana Fierro et al.   CURRENT GENOMICS

ASAS Centennial Paper: Lactation biology for the twenty-first century

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Effects of Inflammatory Conditions on Liver Activity in Puerperium Period and Consequences for Performance in Dairy Cows

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Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-κB in mammary epithelial cells and to quickly induce TNFα and interleukin-8 (CXCL8) expression in the udder

(2008) Wei Yang et al.   MOLECULAR IMMUNOLOGY

The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli

(2008) Adam M Feist et al.   NATURE BIOTECHNOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Evidence for cattle major histocompatibility complex (BoLA) class IIDQA1gene heterozygote advantage against clinical mastitis caused byStreptococciandEscherichiaspecies

(2008) S. Takeshima et al.   TISSUE ANTIGENS

Escherichia coli, but notStaphylococcus aureustriggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow

(2008) Wolfram Petzl et al.   VETERINARY RESEARCH