Article
Polymer Science
Muskan Kanungo, Yale Wang, Noah Hutchinson, Emma Kroll, Anna DeBruine, Subha Kumpaty, Lixia Ren, Yuelin Wu, Xiaolin Hua, Wujie Zhang
Summary: Recent studies have demonstrated the potential of gelatin-coated pectin microspheres for tissue engineering applications, showing promise in promoting vasculature formation and supporting controlled release of bioactive molecules. The concentration of pectin solution was found to impact microsphere roundness and uniformity, while flow rate significantly affected microsphere size.
Article
Chemistry, Physical
Ning Yang, Xiaojing Tian, Yuehong Du, Yumeng Zhang, Qiuli Wang, Ning Ma, Yafei Zhang, Wenhang Wang
Summary: In this study, sodium nitrite-loaded gelatin microspheres and gels were prepared using microbial transglutaminase and their physicochemical properties and antibacterial effects were compared. The microspheres showed better antibacterial effect, achieving the goal of extending the shelf life of meat products.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Biophysics
Shuang Cao, Lin Li, Yan Du, Jufen Gan, Jing Wang, Tao Wang, Ying Liu, Wei Liu, Yejin Zhou, Xin Gao, Hong Li, Tielong Liu
Summary: Research successfully developed Van-MS, which demonstrated high hemostatic and antibacterial efficacy in colloidal structure. Van-MS can achieve antibacterial effects by absorbing exudates and sustained drug release, while possessing multiple hemostatic mechanisms, showing significant effectiveness in soft tissue infections and bleeding.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Polymer Science
Qiao-Qiao Jia, Ya-Xiong Wang, Li Huo, Ying Wang, Li'E Jin
Summary: Gelatin-tannic acid histidine metal complex microspheres were prepared by emulsion cross-linking method to maximize their SOD-like activity and expand their value in the medical field. The encapsulation ratio and encapsulation efficiency of the microspheres were found to be 89.90-93.57% under the optimal conditions. Characterization of the microspheres using IF spectrum, SEM, and particle size analysis showed an average particle size ranging from 5.5 to 14.7 μm for the four types of microspheres. The microspheres demonstrated high antioxidant properties, sustained release effect, and optimal storage temperature and stable kinetic model were obtained.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Engineering, Biomedical
Qingyuan Zhang, Ting Yang, Ruitao Zhang, Xi Liang, Ge Wang, Yuan Tian, Li Xie, Weidong Tian
Summary: Incorporating human platelet lysate and nanoclay Laponite into GelMA microsphere system successfully improved the Young's modulus of the hybrid hydrogel, promoted cell migration and tubule formation, and ultimately facilitated vascularized endodontic regeneration.
ACTA BIOMATERIALIA
(2021)
Article
Polymer Science
Yuya Mizukami, Takuma Yamaguchi, Miki Shiono, Yuki Takahashi, Kazunori Shimizu, Satoshi Konishi, Yoshinobu Takakura, Makiya Nishikawa
Summary: A novel method for fabricating drug-preloaded gelatin microspheres (GMS) using a water-in-water emulsification technique was developed. The drug-loaded GMS showed improved stability, drug-loading efficiency, and sustained release compared to conventional GMS. Incorporation of the drug-loaded GMS into multicellular spheroids enhanced cell viability and improved therapeutic efficacy in a wound healing mouse model.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Chemistry, Medicinal
Truc Cong Ho, Ju-Sop Lim, Shin-Jun Kim, Sung-Yeoul Kim, Byung-Soo Chun
Summary: This study aimed to prepare gelatin-fucoidan microspheres with enhanced doxorubicin binding efficiency and controllable biodegradation. The results showed that subcritical water (SW)-modified gelatin microspheres had smaller particle size, rougher surface, increased swelling ratio, and irregular particle shape. The doxorubicin binding efficiency was improved by fucoidan and SW-modified gelatin at 120 degrees C. The SW modification of fish gelatin increased in vitro enzymatic degradation, possibly due to the formation of weaker cross-linked bonds.
Article
Materials Science, Multidisciplinary
Fengyuan Gao, Tingting Han, Muhammad Rafiq, Luping Chen, Song Wang, Jian Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: In this study, gelatin microspheres (GMs) were prepared as an embolization material that combines silver sulfide quantum dots (Ag2S QDs) and barium sulfate (BaSO4), providing good near-infrared second region (NIR-II) and X-ray imaging effects. The microspheres also demonstrated sustained drug release and rapid embolization properties, making them suitable for tumor therapy. Furthermore, the combination of NIR-II and X-ray multimodal imaging technology in this work shows great potential for clinical embolization applications in biomedical imaging.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Ying Chen, Feng Wei, Wei Mu, Xiaojun Han
Summary: Edible films with different concentrations of eugenol/gelatin microspheres were developed to enhance their antimicrobial properties. The optimum composite films showed compact structure, low water vapor permeability, and low solubility. Eugenol provided the edible films with effective antioxidant and antibacterial activities against E. coli and S. aureus. The prepared films can be used for food packaging applications, allowing the storage of apple cubes at room temperature for 7 days at 50% humidity.
NEW JOURNAL OF CHEMISTRY
(2023)
Review
Cell Biology
Helena Cantwell, Gautam Dey
Summary: This review discusses the cellular properties and processes that contribute to nuclear size and shape control, providing examples from across eukaryotes. It also outlines the physiological roles of specific nuclear morphologies and the disease pathologies associated with aberrant nuclear morphology.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2022)
Article
Chemistry, Applied
Zhirenyong Zhang, Xiaoxue He, Chaoxi Zeng, Qingming Li, Huiping Xia
Summary: This paper reports the preparation and characterization of gelatin-cassava starch microspheres using the water-in-water emulsion technique. The effects of different weight ratios of starch to gelatin on the morphology, structure, thermal properties, and stability of microspheres were investigated. The results showed that the gelatin-cassava starch microspheres had spherical shapes, smooth surfaces, and a stable yolk-shell structure. The swelling capacity increased with the proportion of gelatin, and the crystalline structure of microspheres changed. The microspheres can be used as a potential material for microencapsulation.
CARBOHYDRATE POLYMERS
(2024)
Article
Materials Science, Multidisciplinary
Tomas Soria-Biurrun, Jazmina Navarrete-Cuadrado, Lorena Lozada-Cabezas, Federico Ibarreta-Lopez, Roberto Martinez-Pampliega, Jose M. Sanchez-Moreno
Summary: The hardness and fracture strength of WC-Ni-Co-Cr-Ti-Al cemented carbides can be modified through treatments, with optimized aluminum additions leading to improved mechanical properties. Fe-Ni-Co-Cr alloys may also be potential candidates for partial substitution of Co content in WC-based hardmetals, showing comparable fracture strength values to standard WC-Co grades.
INTERNATIONAL JOURNAL OF REFRACTORY METALS & HARD MATERIALS
(2022)
Review
Engineering, Chemical
Marie-Charlotte Sparenberg, Sara Chergaoui, Vida Sang Sefidi, Patricia Luis
Summary: Membrane distillation-crystallization is a promising method that may outperform conventional crystallization processes in terms of crystallization control and product quality. This review provides a comprehensive overview of the current research on membrane distillation-crystallization, focusing on the impact of different parameters on crystal morphology and quality, as well as discussing control of crystal habit, polymorphism, and other factors.
Article
Engineering, Chemical
Jinyu Shi, Peng Zhu, Jianzhe Liu, Ruiqi Shen, Huanming Xia, Hanyu Jiang, Siyu Xu, Fengqi Zhao
Summary: This study proposes a method to prepare composite energetic microspheres with core-shell structures using oscillating-swirling-coflowing microfluidics and spray drying. The experimental results demonstrate that the superior core-shell structure and spheroidization can be achieved under the cocoating method, and the sensitivity and burning rate of the sample are significantly improved under optimized conditions.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Minjiang Chen, Xiaoju Guo, Lin Shen, Jiayi Ding, Junchao Yu, Xiaoxiao Chen, Fazong Wu, Jianfei Tu, Zhongwei Zhao, Mitsutoshi Nakajima, Jingjing Song, Gaofeng Shu, Jiansong Ji
Summary: Monodispersed gelatin microspheres loaded with calcium carbonate nanoparticles (CaNPs@Gel-MS) were prepared using a simplified microfluidic device. The particle size and homogeneity of the microspheres depended on the flow rates and syringe needle diameter. The introduction of CaNPs enhanced the drug encapsulation ability and pH-responsive drug release behavior of the microspheres.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)