Article
Gastroenterology & Hepatology
John M. DeWitt, Mohammad A. Al-Haddad, Jeffrey J. Easler, Stuart Sherman, James Slaven, Timothy B. Gardner
Summary: Real-time EUS findings and ePFTs significantly impact the clinical assessment of MCCP. The diagnosis of EPI shows poor correlation with the EUS diagnosis of MCCP.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Julio Iglesias-Garcia, Jose Larino-Noia, Laura Nieto, Ana Alvarez-Castro, Santiago Lojo, Saul Leal, Daniel de la Iglesia-Garcia, J. Enrique Dominguez-Munoz
Summary: The study found that EUS-E correlates significantly with ePFT in evaluating patients with suspected chronic pancreatitis, indicating that EUS-E could replace ePFT for the assessment of these patients.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Medicine, General & Internal
Jian-Han Lai, Keng-Han Lee, Chen-Wang Chang, Ming-Jen Chen, Ching-Chung Lin
Summary: This study compared the predictive factors and reliability of computed tomography (CT) and endoscopic ultrasonography (EUS) in patients with pancreatic mass lesions, as well as the diagnostic accuracy of EUS-guided fine needle aspiration (FNA) or fine needle biopsy (FNB) in patients with chronic pancreatitis (CP). The results showed that EUS had superior diagnostic accuracy compared to CT. Hypoattenuation pattern or vessel invasion on CT and pancreatic duct dilatation or distal pancreatic atrophy on EUS were significant predictive factors. The study concluded that EUS imaging is a reliable modality for evaluating pancreatic lesions in patients with CP.
Article
Medicine, General & Internal
Chung-Tsui Huang, Tzong-Hsi Lee, Cheng-Kuan Lin, Chao-Yi Chen, Yi-Feng Yang, Yao-Jen Liang
Summary: This study found that pancreatic fibrosis is a common cause of non-functional dyspepsia, outnumbering peptic ulcer disease in the dyspeptic population. Pancreatic enzyme therapy was effective for 82% of cases. In early chronic pancreatitis, pancreatic fibrosis is dominant in the head location, and duodenum mucosa chromogranin-A may serve as a potential biomarker with increased expression correlating with age.
Article
Gastroenterology & Hepatology
Noriko Inomata, Atsuhiro Masuda, Kohei Yamakawa, Mamoru Takenaka, Masahiro Tsujimae, Hirochika Toyama, Keitaro Sofue, Arata Sakai, Takashi Kobayashi, Takeshi Tanaka, Yasutaka Yamada, Shigeto Ashina, Masanori Gonda, Shohei Abe, Shigeto Masuda, Hisahiro Uemura, Shinya Kohashi, Kae Nagao, Yoshiyuki Harada, Mika Miki, Ryota Nakano, Hideyuki Shiomi, Maki Kanzawa, Tomoo Itoh, Takumi Fukumoto, Yuzo Kodama
Summary: This study reviewed the clinical data of 221 patients with pancreatobiliary tumors who underwent preoperative EUS and pancreatic surgery. The results showed that parenchymal EUS findings were significantly correlated with histological features of fibrosis, inflammation, and atrophy in chronic pancreatitis (CP). It was also observed that lobularity reflected more severe histological conditions than hyperechoic foci/stranding.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Oncology
Guo Tian, Danxia Xu, Yinghua He, Weilu Chai, Zhuang Deng, Chao Cheng, Xinyan Jin, Guyue Wei, Qiyu Zhao, Tianan Jiang
Summary: In recent years, deep learning has played an important role in cancer detection. This study aimed to differentiate pancreatic cancer (PC) or non-pancreatic cancer (NPC) lesions in real-time using endoscopic ultrasonography (EUS) images. By training a model based on EUS images using YOLOv5 algorithm, the study found that the model achieved convergence and showed potential for real-time decision support in distinguishing PC and NPC lesions.
FRONTIERS IN ONCOLOGY
(2022)
Review
Medicine, General & Internal
Yasutaka Ishii, Masahiro Serikawa, Tomofumi Tsuboi, Ryota Kawamura, Ken Tsushima, Shinya Nakamura, Tetsuro Hirano, Ayami Fukiage, Takeshi Mori, Juri Ikemoto, Yusuke Kiyoshita, Sho Saeki, Yosuke Tamura, Sayaka Miyamoto, Kazuaki Chayama
Summary: Endoscopic ultrasonography (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) play important roles in the diagnosis of pancreatic cancer. EUS has higher sensitivity for detecting small pancreatic cancer, while ERCP is essential for evaluating pancreatic duct stricture.
Article
Oncology
Ali Zakaria, Bayan Al-Share, Jason B. Klapman, Aamir Dam
Summary: Pancreatic cancer is a leading cause of cancer-related death in the United States. Early detection and accurate diagnosis are crucial for treatment planning, and endoscopic ultrasonography plays a critical role in the diagnosis and staging of pancreatic cancer.
Article
Gastroenterology & Hepatology
Sandeep Nadella, John G. Lieb
Summary: This study aimed to compare the peak bicarbonate level during secretin stimulation testing among patients with different types of pancreatitis and those without pancreatitis. The study found significant differences in the peak bicarbonate level between different groups, which could be important for diagnosing early-stage pancreatitis.
Review
Gastroenterology & Hepatology
Atsushi Kanno, Tetsurou Miwata, Hiroki Nagai, Eriko Ikeda, Kozue Ando, Yuki Kawasaki, Yamato Tada, Kensuke Yokoyama, Kiichi Tamada, Noriyoshi Fukushima, Alan Kawarai Lefor, Hironori Yamamoto
Summary: Endoscopic ultrasound-guided pancreatic sampling is effective for the histopathological diagnosis of autoimmune pancreatitis and can help distinguish between AIP and pancreatic cancer. Recent advancements in needle biopsy methodologies and technologies have improved the diagnostic efficacy of this technique. The guidance provided in this study is expected to further advance the histopathological diagnosis of AIP using EUS-guided pancreatic sampling.
DIGESTIVE ENDOSCOPY
(2022)
Article
Oncology
Jionghui Gu, Jinhua Pan, Jiayu Hu, Lulu Dai, Ke Zhang, Baohua Wang, Mengna He, Qiyu Zhao, Tianan Jiang
Summary: A deep-learning radiomics (DLR) model based on endoscopic ultrasonography (EUS) images was developed to identify pancreatic ductal adenocarcinoma (PDAC) and explore its true clinical benefit. The test cohort validated the effectiveness of the DLR model, improving the accuracy and diagnostic performance of endosonographers.
Article
Gastroenterology & Hepatology
Masanari Sekine, Akira Tanaka, Maho Akimoto, Takaya Miura, Junichi Fujiwara, Hiroshi Noda, Toshiki Rikiyama, Hirohide Ohnishi, Hirosato Mashima
Summary: The study aimed to examine the association between EUS and pathological findings of the pancreas. The results showed high correlation between EUS findings and pathological findings of chronic inflammation, especially in terms of inflammatory cell infiltration and fibrosis. The accuracy of EUS in detecting lobularity and the hyperechoic margin of the pancreatic duct was also highlighted.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yun Bian, Jian Zhou, Mengmeng Zhu, Jieyu Yu, Haiyan Zhao, Xu Fang, Fang Liu, Tiegong Wang, Jing Li, Li Wang, Jianping Lu, Chengwei Shao
Summary: This study aimed to develop and validate a radiomics nomogram based on a fully automated pancreas segmentation for the assessment of pancreatic exocrine function. The performance of the radiomics nomogram was compared with the pancreatic flow output rate (PFR) and conclusions were drawn on the replacement of secretin-enhanced magnetic resonance cholangiopancreatography (S-MRCP) by the radiomics nomogram for pancreatic exocrine function assessment.
EUROPEAN RADIOLOGY
(2023)
Review
Gastroenterology & Hepatology
Zaheer Nabi, Sundeep Lakhtakia
Summary: Chronic pancreatitis (CP) is characterized by irreversible morphological changes in the pancreas, with pain being the predominant symptom. Endoscopic treatment is effective in relieving pain for a majority of CP patients, with upfront assessment being crucial for optimal outcomes.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Koichi Ito, Yusuke Takasaki, Toshio Fujisawa, Shigeto Ishii, Ko Tomishima, Sho Takahashi, Ippei Ikoma, Yasuhisa Jimbo, Hiroto Ota, Daishi Kabemura, Muneo Ikemura, Mako Ushio, Taito Fukuma, Akinori Suzuki, Hiroyuki Isayama
Summary: The study revealed a low diagnostic rate of early chronic pancreatitis, especially in nonalcoholic cases, but slightly higher in cases presenting with pancreatic pain. The diagnostic rate was highest in the abdominal/back pain group. Further studies are needed to establish appropriate diagnostic criteria for ECP.
