A MINLP approach for layout designs based on the domino hazard index

The Domino Hazard Index used in this work was previously introduced by Tugnoli, Khan, Amyotte, and Cozzani (2008a, 2008b) to assess domino effect hazards caused by a unit in a given layout. This index has been used to compare several layouts in order to select the one with lower risk. A set of piecewise differentiable equations have been developed to describe all graphical descriptions given in the original proposal. Then, this work introduces a complete formulation aimed to achieve optimal facility layouts taking into account the main variables affecting this index. The result of this formulation is a mixed-integer non-linear program (MINLP), which can be solved using a GAMS code. The result can provide substantial support for decision-makers during the design stage. (C) 2013 Elsevier Ltd. All rights reserved.